Paracetamol versus ibuprofen for early postpartum pain control: a randomized controlled trial DOI Creative Commons
Shai Ram,

Dotan Madar,

Hila Shalev‐Ram

и другие.

Archives of Gynecology and Obstetrics, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract Introduction To evaluate the effectiveness of paracetamol and ibuprofen as non-opioid treatments for postpartum pain control after vaginal delivery. Materials methods This randomized controlled study at a university-affiliated medical center involved parturient who received blindly oral tablets either 1000 mg or 400 ibuprofen, post-vaginal birth. Pain levels were assessed using numeric rating scale (NRS) four time points: before treatment, 1, 4, 6 h post-treatment (T0, T1, T4, T6, respectively). We also compared need additional analgesia, breastfeeding initiation, mobilization, urination following delivery between groups. ensure statistical power, was designed to detect differences one point on NRS with least 37 women per group. Results A total 107 participated, including (n = 52) 55) Demographics perinatal outcomes similar across No significant found in interval request (8 ± 6–10.5 11 6–16 respectively, P .13). both groups all intervals. There no group initiation breastfeeding, urination, analgesia. Conclusion Both, can be considered equivalent effective alternatives control. Registry clinicaltrials.gov (NCT04653506), https://register.clinicaltrials.gov/prs/beta/studies/S000AFOR00000066/recordSummary .

Язык: Английский

Acute pain management after vaginal delivery with perineal tears or episiotomy DOI Creative Commons

Xavier Luxey,

Adrien Lemoine, Geertrui Dewinter

и другие.

Regional Anesthesia & Pain Medicine, Год журнала: 2024, Номер unknown, С. rapm - 105478

Опубликована: Май 20, 2024

A vaginal delivery may be associated with acute postpartum pain, particularly after perineal trauma. However, pain management in this setting remains poorly explored.

Язык: Английский

Процитировано

4

NLP-Driven Integration of Electrophysiology and Traditional Chinese Medicine for Enhanced Diagnostics and Management of Postpartum Pain DOI Creative Commons
Yaning Wang

SLAS TECHNOLOGY, Год журнала: 2025, Номер unknown, С. 100267 - 100267

Опубликована: Март 1, 2025

Postpartum pain encompasses a range of physical and emotional discomforts, often influenced by hormonal changes, recovery, individual psychological states. The complex interactions between the variables can make it difficult for traditional diagnostic techniques to fully capture, creating inadequacies inefficient management techniques. aims develop comprehensive framework postpartum integrating Natural Language Processing (NLP), electrophysiological data, Traditional Chinese Medicine (TCM) principles. seeks enhance accuracy diagnosis, uncover meaningful correlations TCM diagnoses physiological markers, optimize personalized treatment strategies. focuses on analyzing textual data from patient-reported symptoms, medical records, diagnosis notes. Data pre-processing involves text cleaning tokenization, followed feature extraction using Term Frequency-Inverse Document Frequency (TF-IDF) capture patterns. For diagnostics management, Refined Coyote Optimized Deep Recurrent Neural Network (RCO-DRNN) is employed analyze predict profiles, combining insights with markers. results highlight effectiveness RCO-DRNN in accurately diagnosing types offering holistic This approach represents significant advancement data-driven methodologies practices, providing more management. continuously beats other models after thorough evaluation metrics like MSE, MAE, R2, obtaining lowest MSE (0.005), smallest MAE (0.04), highest R2 (0.98).

Язык: Английский

Процитировано

0

Association of remifentanil analgesia with postpartum depression and birth experience: an observational study DOI Creative Commons

Fateme Shoureshi Jorbijarkali,

Solmaz Ghanbari‐Homayi, Mojgan Mirghafourvand‬‬‬‬‬‬‬‬‬‬‬‬‬‬

и другие.

BMC Pregnancy and Childbirth, Год журнала: 2025, Номер 25(1)

Опубликована: Май 17, 2025

Pain is a risk factor for postpartum depression. This study aimed to determine the relationship between remifentanil analgesia and depression, as well birth experience among Iranian women. observational was conducted on 200 mothers who underwent vaginal at Taleghani Hospital in Tabriz, Iran, 2023-4. The Edinburgh Postnatal Depression Scale Childbirth Experience Questionnaire were used assess outcomes. To compare childbirth depression exposure group (receiving remifentanil) non-exposure group, independent t-tests Mann-Whitney U tests employed, respectively. mean score statistically significantly lower than that non-analgesia (p = 0.002). total higher < 0.001). Additionally, comparison of subdomains two groups showed scores own capacity 0.001), perceived safety participation 0.001) compared group. However, there no significant difference regarding professional support subdomain 0.434). These findings underscore significance using potential approach preventing creating positive experience. It recommended clinical trials be obtain more precise results.

Язык: Английский

Процитировано

0

The effect of Nigella Sativa emulgel on episiotomy wound healing and pain intensity in primiparous women: A triple-blind randomized controlled trial DOI Creative Commons
Mahsa Maghalian,

Afsaneh Alizadeh,

Fatemeh Raphi

и другие.

PLoS ONE, Год журнала: 2025, Номер 20(6), С. e0325112 - e0325112

Опубликована: Июнь 4, 2025

Background Episiotomy, a common surgical procedure during childbirth, often leads to complications such as pain, infection, and delayed healing. Nigella sativa has demonstrated anti-inflammatory wound-healing properties in prior studies have received United States Food Drug Administration (FDA) approval for food use, indicating their safety. This study aimed evaluate the efficacy of emulgel on episiotomy wound healing pain intensity primiparous women. Methods A triple-blind, randomized controlled trial was conducted at Taleghani Hospital, Tabriz, Iran (May 2023–April 2024). Seventy-four women with mediolateral were receive either or placebo, applied topically three times daily 7 days post-discharge. Wound assessed using REEDA scale (Redness, Edema, Ecchymosis, Discharge, Approximation; primary outcome), measured via visual analog (VAS; secondary outcome). Outcomes evaluated discharge (baseline) 10 ± 1 postpartum. Data analyzed independent t-tests, ANCOVA (adjusted baseline scores), Mann-Whitney U tests non-normal distributions (SPSS v26). Results At postpartum, group showed significantly better (REEDA score: MD −0.79, 95% CI −1.20 −0.39; p = 0.001) lower scores (VAS: −0.74, −1.3 −0.11; 0.021) compared placebo. Subscale analysis revealed improvements redness (p 0.037), edema 0.041), ecchymosis 0.043). No adverse effects reported, satisfaction higher (86.5% vs. 56.7%; 0.046). Conclusions Topical improved reduced intensity, high patient satisfaction. These findings support its potential natural therapeutic option, though larger multi-center trials are needed broader validation. Trial registration Iranian Registry Clinical Trials IRCT20120718010324N68 .

Язык: Английский

Процитировано

0

Paracetamol versus ibuprofen for early postpartum pain control: a randomized controlled trial DOI Creative Commons
Shai Ram,

Dotan Madar,

Hila Shalev‐Ram

и другие.

Archives of Gynecology and Obstetrics, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract Introduction To evaluate the effectiveness of paracetamol and ibuprofen as non-opioid treatments for postpartum pain control after vaginal delivery. Materials methods This randomized controlled study at a university-affiliated medical center involved parturient who received blindly oral tablets either 1000 mg or 400 ibuprofen, post-vaginal birth. Pain levels were assessed using numeric rating scale (NRS) four time points: before treatment, 1, 4, 6 h post-treatment (T0, T1, T4, T6, respectively). We also compared need additional analgesia, breastfeeding initiation, mobilization, urination following delivery between groups. ensure statistical power, was designed to detect differences one point on NRS with least 37 women per group. Results A total 107 participated, including (n = 52) 55) Demographics perinatal outcomes similar across No significant found in interval request (8 ± 6–10.5 11 6–16 respectively, P .13). both groups all intervals. There no group initiation breastfeeding, urination, analgesia. Conclusion Both, can be considered equivalent effective alternatives control. Registry clinicaltrials.gov (NCT04653506), https://register.clinicaltrials.gov/prs/beta/studies/S000AFOR00000066/recordSummary .

Язык: Английский

Процитировано

0