Beyond Tuberculosis: The Surprising Immunological Benefits of the Bacillus Calmette–Guérin (BCG) Vaccine in Infectious, Auto-Immune, and Inflammatory Diseases

Pathogens, Год журнала: 2025, Номер 14(2), С. 196 - 196

Опубликована: Фев. 15, 2025

The Bacillus Calmette-Guérin (BCG) vaccine, best known for its role in preventing tuberculosis, has recently garnered attention broader immunomodulatory effects. By inducing trained immunity, BCG reprograms innate immune cells, enhancing their responses to various pathogens. This process, driven by epigenetic and metabolic reprogramming, suggests that may have therapeutic potential far beyond tuberculosis. Emerging evidence points benefits conditions such as autoimmune diseases, cancer, viral infections. Furthermore, modulating activity, been proposed reduce chronic inflammation promote tolerance. review delves into the multifaceted of BCG, highlighting a versatile tool managing wide range diseases.

Язык: Английский

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Le BCG pourrait atténuer les symptômes du Covid long

Option/Bio, Год журнала: 2025, Номер 36(701-702), С. 12 - 12

Опубликована: Март 1, 2025

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