Phytochemical Profiling and Health Benefits of Chloroform and Methanol Extracts of <i>Laurus nobilis</i> (Bay Leaf) DOI Open Access

Ngozi Offor,

Bruno Chukwuemeka Chinko

International Journal of Biomedical Materials Research, Год журнала: 2025, Номер 13(1), С. 10 - 23

Опубликована: Март 26, 2025

<i>Background:</i> <i>Laurus nobilis, </i>commonly known as bay leaf, is widely used in global cuisine for flavouring soups and stews, well baked foods desserts. The present study aims to characterize the phytochemical composition of chloroform methanol extracts nobilis</i> using Gas Chromatography-Mass Spectrometry (GC–MS) analysis. <i>Materials Methods:</i> Dried Bay leaves were locally sourced, properly identified, authenticated. extracted cold maceration obtain (CELN) (MELN) nobilis</i>. Qualitative quantitative screening, along with (GC-MS) analysis, was performed following standard protocols. <i>Results:</i> qualitative analysis CELN MELN confirmed presence flavonoids, phenols, terpenoids, glycosides, steroids, saponins, alkaloids, carbohydrates. Quantitative indicated that contained higher levels phenols (11.34 mg/100g), tannins (5.20 carbohydrates (16.23 mg/100g). GC-MS identified 87 98 compounds MELN, respectively, 10 common both extracts. most abundant (≥5%) Spiro(1,3,3-trimethylindoline)-2,5’-pyrrolidin-2-one (8.35%), 7,10,13-Hexadecatrienoic acid, methyl ester (12.75%), Azuleno(4,5-b)furan-2(3H)-one, 3a,4,6a,7,8,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene) (9.09%), n-Hexadecenoic acid (18.25%). For CELN, Buta-1,3-diyne,1,4-bis(2-methoxycarbonylcyclopropyl) (5.11%), Azuleno[6,5-b]furan-2,5-dione, decahydro-4a,8-dimethyl-3-methylene-,3aR-(3aα,4a,7aα,8β,9aα) (5.75%), n-Hexadecanoic (5.89%), phytol (7.57%), Benzene, 1-phenyl-4-(2,2-dicyanoethenyl) (13.91%). <i>Conclusion:</i> This highlights rich bioactive profile (bay leaf) extracts, reinforcing their potential disease management. It also underscores need comprehensive pharmacological investigations its support drug discovery efforts.

Язык: Английский

Phytochemical Profiling and Health Benefits of Chloroform and Methanol Extracts of <i>Laurus nobilis</i> (Bay Leaf) DOI Open Access

Ngozi Offor,

Bruno Chukwuemeka Chinko

International Journal of Biomedical Materials Research, Год журнала: 2025, Номер 13(1), С. 10 - 23

Опубликована: Март 26, 2025

<i>Background:</i> <i>Laurus nobilis, </i>commonly known as bay leaf, is widely used in global cuisine for flavouring soups and stews, well baked foods desserts. The present study aims to characterize the phytochemical composition of chloroform methanol extracts nobilis</i> using Gas Chromatography-Mass Spectrometry (GC–MS) analysis. <i>Materials Methods:</i> Dried Bay leaves were locally sourced, properly identified, authenticated. extracted cold maceration obtain (CELN) (MELN) nobilis</i>. Qualitative quantitative screening, along with (GC-MS) analysis, was performed following standard protocols. <i>Results:</i> qualitative analysis CELN MELN confirmed presence flavonoids, phenols, terpenoids, glycosides, steroids, saponins, alkaloids, carbohydrates. Quantitative indicated that contained higher levels phenols (11.34 mg/100g), tannins (5.20 carbohydrates (16.23 mg/100g). GC-MS identified 87 98 compounds MELN, respectively, 10 common both extracts. most abundant (≥5%) Spiro(1,3,3-trimethylindoline)-2,5’-pyrrolidin-2-one (8.35%), 7,10,13-Hexadecatrienoic acid, methyl ester (12.75%), Azuleno(4,5-b)furan-2(3H)-one, 3a,4,6a,7,8,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene) (9.09%), n-Hexadecenoic acid (18.25%). For CELN, Buta-1,3-diyne,1,4-bis(2-methoxycarbonylcyclopropyl) (5.11%), Azuleno[6,5-b]furan-2,5-dione, decahydro-4a,8-dimethyl-3-methylene-,3aR-(3aα,4a,7aα,8β,9aα) (5.75%), n-Hexadecanoic (5.89%), phytol (7.57%), Benzene, 1-phenyl-4-(2,2-dicyanoethenyl) (13.91%). <i>Conclusion:</i> This highlights rich bioactive profile (bay leaf) extracts, reinforcing their potential disease management. It also underscores need comprehensive pharmacological investigations its support drug discovery efforts.

Язык: Английский

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