Light
contains
different
wavelengths
of
the
spectrum
that
are
detected
and
received
by
photoreceptor
cells
(rod
cone
cells)
in
retina.
However,
light
serves
non-visual
functions
human
perception,
such
as
emotion
regulation,
cognitive
performance,
sleep
cycle,
hormone
production.
These
alter
brain
activity
oxygen
consumption
brain.
Our
objective
was
to
investigate
effect
on
using
NIRS.
Ten
subjects
(8
males,
2
females)
with
normal
color
vision
were
exposed
achromatic
(white
gray)
or
chromatic
(blue,
green,
yellow,
red)
for
20
seconds
random
order,
followed
30
rest
(dim
light).
This
stimulation-rest
cycle
repeated
4
times
(total
time
=
20.30
minutes).
NIRS
used
measure
Oxy-Hb,
Deoxy-Hb,
Total-Hb
levels
frontal
lobe
during
stimulation.
After
stimulation,
participants
assessed
BRUMS
a
effectiveness
test.
The
results
indicated
z-score
Oxy-Hb
significantly
altered
response
gray
compared
white
light.
Red
blue
led
greater
than
green
yellow
there
no
significant
Deoxy-Hb
both
exposure.
Gray
induced
feelings
depression
confusion,
while
red
affected
tension
anger.
promoted
vigor.
Fatigue
did
not
show
difference
between
Additionally,
long
had
more
positive
short
wavelengths.
findings
indicate
possible
uses
neurotherapeutic
interventions
stimulating
individuals
impairments
therapy
boxes,
well
architectural
lighting
design
impact
regulation.
Journal of Sleep Research,
Год журнала:
2023,
Номер
32(6)
Опубликована: Ноя. 28, 2023
Summary
Progress
in
the
field
of
insomnia
since
2017
necessitated
this
update
European
Insomnia
Guideline.
Recommendations
for
diagnostic
procedure
and
its
comorbidities
are:
clinical
interview
(encompassing
sleep
medical
history);
use
questionnaires
diaries
(and
physical
examination
additional
measures
where
indicated)
(A).
Actigraphy
is
not
recommended
routine
evaluation
(C),
but
may
be
useful
differential‐diagnostic
purposes
Polysomnography
should
used
to
evaluate
other
disorders
if
suspected
(i.e.
periodic
limb
movement
disorder,
sleep‐related
breathing
disorders,
etc.),
treatment‐resistant
(A)
indications
(B).
Cognitive‐behavioural
therapy
as
first‐line
treatment
chronic
adults
any
age
(including
patients
with
comorbidities),
either
applied
in‐person
or
digitally
When
cognitive‐behavioural
sufficiently
effective,
a
pharmacological
intervention
can
offered
Benzodiazepines
(A),
benzodiazepine
receptor
agonists
daridorexant
low‐dose
sedating
antidepressants
(B)
short‐term
(≤
4
weeks).
Longer‐term
these
substances
initiated
some
cases,
considering
advantages
disadvantages
Orexin
antagonists
periods
up
3
months
longer
cases
Prolonged‐release
melatonin
≥
55
years
Antihistaminergic
drugs,
antipsychotics,
fast‐release
melatonin,
ramelteon
phytotherapeutics
are
Light
exercise
interventions
adjunct
therapies
Deutsches Ärzteblatt international,
Год журнала:
2023,
Номер
unknown
Опубликована: Дек. 6, 2023
Good
sleep
is
correlated
with
health.
Primary
insomnia
a
common
reason
for
consulting
primary
care
physician.
It
usually
treated
drugs
despite
clear
evidence
the
efficacy
of
behavioral
therapy.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Янв. 2, 2025
Sleep
disorders
constitute
a
significant
disruption
for
shift
workers.
Beyond
medical
interventions,
phototherapy
is
recognized
as
an
effective
approach
to
significantly
alleviate
sleep
disorders,
particularly
among
individuals
engaged
in
work.
However,
the
dose
and
efficacy
evaluation
of
have
not
yet
been
determined.
This
study
conducted
systematic
review
across
five
databases
from
January
1,
1990,
December
31,
2023.
A
total
11
articles
were
selected
meta-analysis
using
random-effects
model.
The
results
showed
that
light
therapy
improved
time
(TST)
(MD
=
32.54,
p
<
0.00001)
efficiency
(SE)
2.91,
0.007)
workers
compared
control
group.
Subgroup
analysis
regression
implied
medium
illuminance
(900–6000
lx)
long
treatment
duration
(≥
1
h)
during
night
was
more
extending
time,
whereas
higher-illuminance
increasing
(lx*h)
beneficial
SE.
In
summary,
has
degree
overall
workers,
findings
current
contribute
reference
evidence
setting
experimental
design
on
workers'
clinical
research.
Journal of Sleep Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 31, 2025
Insomnia
disorder,
characterized
by
a
complaint
of
reduced
sleep
quality
or
quantity
and
associated
daytime
impairment,
is
highly
prevalent
with
life
productivity.
Cognitive
behavioural
therapy
for
insomnia
(CBT-I)
the
current
first-line
treatment
chronic
disorder.
Here,
we
outline
our
perspective
future
optimization
psychotherapeutic
insomnia.
We
identified
following
areas
as
most
promising:
first,
optimizing
efficacy
CBT-I
protocol;
second,
developing
diagnostic
therapeutic
approaches
non-responders
partial
responders;
third,
advancing
widespread
implementation
psychotherapy
More
specifically,
how
protocol
could
be
optimized
through
an
improved
understanding
mechanisms,
discuss
potential
adaptive
strategies.
Another
promising
approach
improving
using
add-ons
such
physical
exercise
circadian-based
interventions.
Both
may
in
certain
subgroups
patients
In
terms
non-response,
identify
acceptance
commitment
(ACT-I)
to
CBT-I.
ACT-I,
however,
still
needs
evaluated
actual
Implementing
clinical
practice
one
major
challenges
at
hand.
brief
treatment,
targeted
challenging
patient
groups,
digital
help
improve
implementation.
For
research
agenda,
suggest
that
further
into
randomized-controlled
trials
CBT-I,
focus
on
science
have
bring
field
forward.
Brain and Behavior,
Год журнала:
2025,
Номер
15(2)
Опубликована: Фев. 1, 2025
ABSTRACT
Purpose
To
provide
a
comprehensive
review
of
sleep
disturbances
in
hospitalized
patients,
focusing
on
case‐based
approach
to
illustrate
the
multifaceted
nature
this
clinical
challenge.
Method
An
extensive
related
literature
was
conducted
determine
common
causes
such
as
environmental,
medical,
psychological,
and
physiological
factors.
The
case
Mrs.
Z
used
how
these
factors
interact
setting.
Findings
study
revealed
high
prevalence
which
can
lead
significant
adverse
outcomes.
A
multidisciplinary
involving
physicians,
nurses,
pharmacists,
other
healthcare
professionals
is
essential
effectively
manage
disorders
due
interplay
various
Nonpharmacological
interventions
are
fundamental
management
plan.
Pharmacotherapy
may
sometimes
be
necessary
improve
quality
duration.
Conclusion
Health
significantly
enhance
piatients
by
understanding
value
providing
evidence‐based
strategies
for
improvement.
In
return,
improves
patient
outcomes,
reduces
costs,
advances
general
satisfaction.
Medicina,
Год журнала:
2024,
Номер
60(4), С. 632 - 632
Опубликована: Апрель 14, 2024
Background:
Insomnia
is
increasingly
recognized
for
its
marked
impact
on
public
health
and
often
associated
with
various
adverse
outcomes,
including
cardiovascular
diseases
mental
disorders.
The
aim
of
this
study
was
to
investigate
the
efficacy
pre-sleep
dim
light
therapy
(LT)
as
a
non-pharmacological
intervention
insomnia
in
adults,
assessing
influence
sleep
parameters
circadian
rhythms.
Methods:
A
randomized,
open-label,
two-arm
clinical
trial
conducted
over
two
weeks
40
participants
aged
20–60
years,
all
whom
had
disorders
(CRIS,
KCT0008501).
They
were
allocated
into
control
LT
groups.
group
received
exposure
warm-colored
light,
minimizing
blue
spectrum,
before
bedtime.
combined
subjective
evaluation
via
validated,
sleep-related
questionnaires,
objective
assessments
actigraphy,
molecular
analyses
clock
gene
expression
peripheral
blood
mononuclear
cells.
Baseline
characteristics
between
groups
compared
using
an
independent
t-test
continuous
variables
chi-squared
test
categorical
variables.
Within-group
differences
assessed
paired
t-test.
Changes
analyzed
linear
regression,
adjusting
each
baseline
value
body
mass
index.
patterns
changes
calculated
mixed
model.
Results:
exhibited
significant
improvements
quality
(difference
difference
[95%
CI];
−2.00
[−3.58,
−0.43],
efficiency
(LT:
84.98
vs.
control:
82.11,
p
=
0.032),
advanced
Dim
Light
Melatonin
Onset
(approximately
30
min).
Molecular
analysis
indicated
reduction
CRY1
after
LT,
suggesting
signals
regulation.
Conclusions:
This
provides
evidence
improving
rhythm
alignment
adults
insomnia.
Despite
limitations,
such
small
sample
size
short
duration,
results
underscore
potential
viable
approach
Future
research
should
expand
these
larger
more
diverse
cohorts
followed
longer
period
validate
further
elucidate
medicine.
Trial
registration:
registered
Clinical
Research
Information
Service
(KCT0008501).
