Journal of Natural Fibers,
Год журнала:
2024,
Номер
21(1)
Опубликована: Фев. 21, 2024
In
this
study,
ultra-high
performance
liquid
chromatography-tandem
mass
spectrometry
was
used
to
isolate
and
identify
terpenoids
in
three
types
of
pineapple
fibers
(pineapple
leaf
fiber,
stem
root
fiber).
The
research
results
showed
that
the
positive
negative
ion
modes,
9
26
terpenoid
compounds
were
identified
from
fibers,
totaling
35
species
12
categories,
among
which
triterpene
saponins
had
largest
number
species.
Pineapple
fiber
contains
highest
total
content,
followed
by
fiber.
OPLS-DA
model,
VIP
S-plot
methods
revealed
differences
fibers.
there
9,
8
7
significantly
different
respectively.
Functional
such
as
ivy
saponin,
dehydroabietic
acid,
myrcene
ginsenoside
are
distributed
parts
with
varying
degrees
enrichment.
This
study
provides
a
basis
for
differentiated
utilization
value-added
use
leaves,
stems
roots.
Utilization
scientific
basis.
Applied Microbiology and Biotechnology,
Год журнала:
2024,
Номер
108(1)
Опубликована: Фев. 7, 2024
Abstract
The
increasing
antibiotic
resistance
towards
a
panel
of
microorganisms
is
one
the
public
health
concerns.
For
this
reason,
search
for
alternatives
to
widely
used
has
been
undertaken.
In
era
sustainable
chemistry,
deep
eutectic
solvents
(DESs)
have
emerged
as
promising
antimicrobial
agents.
These
possess
several
advantages
such
low
volatility,
flammability,
ease
preparation,
and
typically
cost
production.
properties
make
DES
suitable
various
applications,
including
extraction
biomolecules
preparation
cosmetics.
Natural
DESs
(NADESs)
are
special
category
prepared
from
natural
sources,
which
matched
recent
trends
leaning
back
nature,
decreasing
dependence
on
synthetic
precursors.
NADES
can
be
by
heating
stirring,
freeze-drying,
evaporation,
grinding,
ultrasound-assisted
microwave-assisted
synthesis.
Utilizing
NADESs
an
alternative
traditional
antibiotics,
become
ineffective
over
time
due
bacterial
resistance,
holds
great
promise
these
reasons.
This
review
aims
discuss
multiple
NADESs,
antibacterial
antifungal
activities.
To
best
our
knowledge,
first
literature
survey
activities
NADESs.
Key
points
•
antibiotics
high
potential
their
activity
against
also
substantial
The Analyst,
Год журнала:
2023,
Номер
148(14), С. 3130 - 3152
Опубликована: Янв. 1, 2023
More
environment-friendly
solvents
in
analytical
chemistry
are
almost
inevitable
both
sample
preparation
and
analysis
to
meet
the
high
standards
of
sustainable
human
welfare.
Molecules,
Год журнала:
2023,
Номер
28(5), С. 2402 - 2402
Опубликована: Март 6, 2023
Deep
eutectic
solvents
(DESs)
and
ionic
liquids
(ILs)
offer
novel
opportunities
for
several
pharmaceutical
applications.
Their
tunable
properties
control
over
their
design
Choline
chloride
(CC)-based
DESs
(referred
to
as
Type
III
eutectics)
superior
advantages
various
therapeutic
Here,
CC-based
of
tadalafil
(TDF),
a
selective
phosphodiesterase
type
5
(PDE-5)
enzyme
inhibitor,
were
designed
implementation
in
wound
healing.
The
adopted
approach
provides
formulations
the
topical
application
TDF,
hence
avoiding
systemic
exposure.
To
this
end,
chosen
based
on
suitability
application.
Then,
DES
TDF
prepared,
yielding
tremendous
increase
equilibrium
solubility
TDF.
Lidocaine
(LDC)
was
included
formulation
with
provide
local
anaesthetic
effect,
forming
F01.
addition
propylene
glycol
(PG)
attempted
reduce
viscosity,
F02.
fully
characterised
using
NMR,
FTIR
DCS
techniques.
According
obtained
characterisation
results,
drugs
soluble
no
detectable
degradation.
Our
results
demonstrated
utility
F01
healing
vivo
cut
burn
models.
Significant
retraction
area
observed
within
three
weeks
when
compared
DES.
Furthermore,
utilisation
resulted
less
scarring
wounds
than
any
other
group
including
positive
control,
thus
rendering
it
candidate
formula
dressing
formulations.
We
that
slower
process
associated
potential.
Lastly,
antimicrobial
activity
against
panel
fungi
bacterial
strains,
providing
unique
via
simultaneous
prevention
infection.
In
conclusion,
work
presents
vehicle
biomedical
ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(18), С. 7187 - 7199
Опубликована: Апрель 24, 2024
Natural
deep
eutectic
solvents
(NaDES),
a
category
of
sustainable
made
from
biorefinery
ingredients,
are
an
eco-friendly
alternative
to
organic
in
solubilization
active
pharmaceutical
or
cosmetic
ingredients.
Biocompatible
NaDES
can
be
introduced
final
products
but
prone
modify
their
properties
thanks
hydrogen
bonding
capacities.
The
present
study
focuses
on
the
impact
incorporation
two
hydrophilic
betaine
and
glycerol
(BG)
citric
acid
glucose
(CG),
carboxymethylcellulose
(CMC)-based
hydrogel.
Differential
scanning
calorimetry
revealed
that
did
not
affect
endothermic
peak
water
eliminated
associated
with
CMC
polymer
chain
loosening.
Rheological
analysis
displayed
shear-thinning
behavior,
while
addition
10%
wt
led
significant
increase
viscosity
at
rest.
CG
introduction
shift
viscous-dominant
behavior
elastic-dominant
strengthening
cohesion
gel
structure.
Texture
analyses
NaDES-containing
gels
exhibit
higher
hardness
elasticity.
Sensory
evaluations
highlighted
differences
five
sensory
attributes
among
concentrations
types
playing
roles.
This
research
underscores
intricate
interplay
between
hydrogel
properties,
offering
insights
into
formulation
innovative
achieve
both
solubility
appeal.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(10), С. 8492 - 8492
Опубликована: Май 9, 2023
Over
the
last
years,
we
observed
a
significant
increase
in
number
of
published
studies
that
focus
on
synthesis
and
characterization
deep
eutectic
solvents
(DESs).
These
materials
are
particular
interest
mainly
due
to
their
physical
chemical
stability,
low
vapor
pressure,
ease
synthesis,
possibility
tailoring
properties
through
dilution
or
change
ratio
parent
substances
(PS).
DESs,
considered
as
one
greenest
families
solvents,
used
many
fields,
such
organic
(bio)catalysis,
electrochemistry,
(bio)medicine.
DESs
applications
have
already
been
reported
various
review
articles.
However,
these
reports
described
components’
basics
general
without
focusing
particular,
PS-wise,
group
DESs.
Many
investigated
for
potential
(bio)medical
comprise
acids.
different
aims
studies,
not
yet
thoroughly,
which
makes
it
challenging
field
move
forward.
Herein,
propose
distinguishing
comprising
acids
(OA-DESs)
specific
derived
from
natural
(NADESs).
This
highlight
compare
OA-DESs
antimicrobial
agents
drug
delivery
enhancers—two
essential
fields
where
implemented
proven
potential.
From
survey
literature
data,
is
evident
represent
an
excellent
type
biomedical
applications,
owing
negligible
cytotoxicity,
fulfilling
rules
green
chemistry
being
generally
effective
enhancers
agents.
The
main
most
intriguing
examples
(where
possible)
application-based
comparison
groups
OA-DESs.
should
importance
give
valuable
clues
direction
can
take.
International Journal of Environmental Health Research,
Год журнала:
2024,
Номер
unknown, С. 1 - 22
Опубликована: Июль 5, 2024
The
present
investigation
examines
the
antimicrobial
and
antifungal
characteristics
of
natural
deep
eutectic
solvents
(NADES)
apple
vinegar
in
relation
to
a
diverse
array
bacterial
fungal
strains.
clinical
strains,
including
gram-negative
gram-positive,
pathogen
Candida
albicans,
were
subjected
solid
medium
diffusion
determine
inhibitory
effects
these
compounds.
results
show
that
NADES
has
superior
action
compared
vinegar.
observed
zones
for
varied
length
from
16.5
24.2
16
52.5
mm,
respectively.
obtained
indicate
no
synergy
is
this
mixture
(50%
AV
+
50%
NADES).
range
values
bactericidal
concentrations
(MBC)
minimal
(MIC)
was
0.0125
0.2
0.4
µl/ml,
Antibacterial
chemicals
may
be
found
NADES,
with
offering
environmentally
safe
substitutes
traditional
antibiotics.
Additional
suggested
refine
compounds
wide
bacteria,
which
could
create
solutions
are
both
highly
effective
specifically
targeted,
thereby
extensive
potential
medicine
environment.
