Plant cell wall-mediated disease resistance: Current understanding and future perspectives
Molecular Plant,
Год журнала:
2024,
Номер
17(5), С. 699 - 724
Опубликована: Апрель 9, 2024
Язык: Английский
The molecular structure, biological roles, and inhibition of plant pathogenic fungal chitin deacetylases
Frontiers in Plant Science,
Год журнала:
2024,
Номер
14
Опубликована: Янв. 9, 2024
Chitin/polysaccharide
deacetylases
belong
to
the
carbohydrate
esterases
family
4
(CE4
enzymes).
They
play
a
crucial
role
in
modifying
physiochemical
characteristics
of
structural
polysaccharides
and
are
also
involved
wide
range
biological
processes
such
as
fungal
autolysis,
spore
formation,
cell
wall
formation
integrity,
germling
adhesion.
These
enzymes
mostly
common
fungi,
marine
bacteria,
limited
number
insects.
facilitate
deacetylation
chitin
which
is
biopolymer
that
abundantly
found
walls
spores
cuticle
peritrophic
matrices
The
exhibit
specificity
towards
substrate
containing
sequence
four
GlcNAc
units,
with
one
these
units
being
subjected
deacetylation.
Chitin
results
chitosan,
poor
for
host
plant
chitinases,
therefore
it
can
suppress
immune
response
triggered
by
pathogens
enhance
pathogen
virulence
colonization.
This
review
discusses
pathogenic
chitin/polysaccharide
including
their
structure,
specificity,
roles
some
recently
discovered
deacetylase
inhibitors
help
mitigate
diseases.
provides
fundamental
knowledge
will
undoubtedly
lead
rational
design
novel
target
deacetylases,
aid
management
diseases,
thereby
safeguarding
global
food
security.
Язык: Английский
Global transcriptome changes during growth of a novel Penicillium coffeae isolate on the wheat stripe rust fungus, Puccinia striiformis f. sp. tritici
Fungal Genetics and Biology,
Год журнала:
2025,
Номер
176, С. 103956 - 103956
Опубликована: Янв. 17, 2025
Язык: Английский
A chitin deacetylase PsCDA2 from Puccinia striiformis f. sp. tritici confers disease pathogenicity by suppressing chitin‐triggered immunity in wheat
Molecular Plant Pathology,
Год журнала:
2023,
Номер
24(12), С. 1467 - 1479
Опубликована: Июль 24, 2023
Abstract
Plants
have
the
ability
to
recognize
essential
chitin
molecule
present
in
fungal
cell
wall,
which
stimulates
immune
response.
Phytopathogenic
fungi
developed
various
strategies
inhibit
chitin‐triggered
Here,
we
identified
a
deacetylase
of
Puccinia
striiformis
f.
sp.
tritici
(Pst),
known
as
Ps
CDA2,
that
was
induced
during
initial
invasion
wheat
and
acted
an
inhibitor
plant
death.
Knockdown
CDA2
enhanced
its
resistance
against
Pst,
highlighting
significance
host–pathogen
interaction.
Moreover,
can
protect
Pst
urediniospores
from
being
damaged
by
host
chitinase
vitro.
also
suppressed
basal
chitin‐induced
response,
including
accumulation
callose
expression
defence
genes.
Overall,
our
results
demonstrate
secretes
involved
establishing
infection
modifying
acetyl
group
prevent
breakdown
wall
endogenous
chitinases.
Our
research
unveils
mechanism
fungus
suppresses
immunity,
further
contributing
understanding
stripe
rust
control.
This
information
could
significant
implications
for
development
suitable
protecting
crops
devastating
effects
this
disease.
Язык: Английский
Chitins and chitosans–A tale of discovery and disguise, of attachment and attainment
Current Opinion in Plant Biology,
Год журнала:
2024,
Номер
82, С. 102661 - 102661
Опубликована: Ноя. 12, 2024
Chitin
polymers
are
an
essential
structural
component
of
fungal
cell
walls,
but
host
chitinases
can
weaken
them,
contributing
to
disease
resistance
in
pathogens.
oligomers
thus
produced
immunogenic
signal
molecules
eliciting
additional
mechanisms.
Fungi
may
counteract
these,
e.g.
by
partial
deacetylation
chitin,
converting
it
into
chitosans,
protecting
the
walls
against
chitinase
attack,
and
inactivating
elicitor
active
oligomers.
This
molecular
stealth
hypothesis
for
pathogenicity
has
repeatedly
been
tested
mutating
single
or
multiple
chitin
deacetylase
genes,
supporting
simultaneously
suggesting
roles
virulence,
such
as
surface
attachment
sensing,
tissue
penetration
colonization,
well
spore
formation,
stabilization,
germination.
Interestingly,
recent
evidence
suggests
that
plants
have
evolved
counter
strategies
inhibiting
deacetylases,
lending
further
credibility
suggested
action
these
enzymes
pathogenicity/virulence
factors,
possibly
offering
leads
toward
novel
functional
fungicides.
Язык: Английский
Fungal Cell Wall-Associated Effectors: Sensing, Integration, Suppression, and Protection
Molecular Plant-Microbe Interactions,
Год журнала:
2023,
Номер
37(3), С. 196 - 210
Опубликована: Ноя. 13, 2023
The
cell
wall
(CW)
of
plant-interacting
fungi,
as
the
direct
interface
with
host
plants,
plays
a
crucial
role
in
fungal
development.
A
number
secreted
proteins
are
directly
associated
CW,
either
through
covalent
or
non-covalent
interactions,
and
serve
range
important
functions.
In
context
plant–fungal
interactions
many
for
development
environment
may
therefore
be
considered
CW-associated
effectors
(CWAEs).
Key
CWAE
functions
include
integrating
chemical/physical
signals
to
hyphal
growth,
interfering
plant
immunity,
providing
protection
against
defenses.
recent
years,
diverse
mechanisms
have
been
reported
that
underpin
their
roles,
some
CWAEs
harboring
conserved
motifs
functional
domains,
while
others
novel
features.
As
such,
current
understanding
regarding
is
systematically
presented
here
from
perspective
biological
interactions.
An
overview
CW
architecture
by
which
secreted,
modified,
incorporated
into
first
provide
roles.
Some
across
broad
pathosystems
symbiotic/mutualistic
associations.
Prominent
chitin
interacting-effectors
facilitate
modification,
protection,
suppression
immune
responses.
However,
several
alternative
now
discussed.
can
play
possibly
unique
lineages
fungi.
[Formula:
see
text]
Copyright
©
2024
Author(s).
This
an
open
access
article
distributed
under
CC
BY
4.0
International
license
.
Язык: Английский