Molecules,
Год журнала:
2023,
Номер
28(15), С. 5889 - 5889
Опубликована: Авг. 5, 2023
Nanoemulsion
is
a
new
multi-component
drug
delivery
system;
the
selection
of
different
oil
phases
can
give
it
special
physiological
activity,
and
play
role
"medicine
pharmaceutical
excipients
all-in-one".
In
this
paper,
we
used
glycyrrhizic
acid
as
natural
surfactant,
Blumea
balsamifera
(BB)
tea
tree
(TTO)
mixed
phase,
to
obtain
green
functional
composite
nanoemulsion.
Using
average
particle
size
polydispersion
index
(PDI)
evaluation
criteria,
effects
ratio,
content,
concentration,
ultrasonic
time
on
nanoemulsion
were
systematically
investigated.
The
stability
physicochemical
properties
biological
activities
BB-TTO
NEs
prepared
via
optimum
formulation
characterized.
optimal
prescription
was
BB:
TTO
=
1:1,
5%
0.7%
acid,
5
min
ultrasonication
time.
mean
size,
PDI,
zeta
potential
160.01
nm,
0.125,
-50.94
mV,
respectively.
showed
non-significant
changes
in
after
centrifugation,
dilution,
120
days
storage.
These
nanoemulsions
found
exhibit
antibacterial
anti-inflammatory
activities.
minimal
inhibitory
concentration
(MIC)
against
Escherichia
coli,
Staphylococcus
aureus,
Pseudomonas
aeruginosa
2975
μg/mL,
5950
A
lower
level
inflammatory
cell
infiltration
proportion
fibrosis
synovial
tissue
AIA
rats
treated
with
NEs.
findings
demonstrate
that
produced
study
have
significant
for
usage
areas.
Abstract
Background
Aquaculture
plays
an
important
role
in
global
protein
supplies
and
food
security.
The
ban
on
antibiotics
as
feed
additive
proposes
urgent
need
to
develop
alternatives.
Gut
microbiota
roles
the
metabolism
immunity
of
fish
has
potential
give
rise
novel
solutions
for
challenges
confronted
by
culture.
However,
our
understanding
gut
microbiome
is
still
lacking.
Results
We
identified
575,856
non-redundant
genes
metagenomic
sequencing
intestinal
content
samples
grass
carp.
Taxonomic
functional
annotation
gene
catalogue
revealed
specificity
carp
compared
with
mammals.
Co-occurrence
analysis
indicated
exclusive
relations
between
genera
belonging
Proteobacteria
Fusobacteria/Firmicutes/Bacteroidetes
,
suggesting
two
independent
ecological
groups
microbiota.
association
pattern
expression
modules
liver
was
consistently
opposite
that
Fusobacteria
Firmicutes
Bacteroidetes
implying
differential
functionality
/
.
Therefore,
were
considered
groups,
i.e.,
Functional
Group
1:
2:
Further
differ
genetic
capacity
carbohydrate
utilization,
virulence
factors,
antibiotic
resistance.
Finally,
we
proposed
ratio
“Functional
2/Functional
1”
can
be
used
a
biomarker
efficiently
reflects
structural
characteristics
Conclusions
resource
investigating
Multi-omics
provides
insights
into
implications
main
phyla
comprise
shed
lights
targets
regulation.
Frontiers in Plant Science,
Год журнала:
2023,
Номер
14
Опубликована: Янв. 18, 2023
Medicinal
plants
are
natural
sources
to
unravel
novel
bioactive
compounds
satisfy
human
pharmacological
potentials.
The
world’s
demand
for
herbal
medicines
is
increasing
year
by
year;
however,
large-scale
production
of
medicinal
and
their
derivatives
still
limited.
rapid
development
modern
technology
has
stimulated
multi-omics
research
in
plants,
leading
a
series
breakthroughs
on
key
genes,
metabolites,
enzymes
involved
biosynthesis
regulation
active
compounds.
Here,
we
summarize
the
latest
progress
molecular
intricacy
including
comparison
genomics
demonstrate
variation
evolution
among
species,
application
transcriptomics,
proteomics
metabolomics
explore
dynamic
changes
compounds,
utilization
potential
resources
drug
discovery.
These
provide
theoretical
basis
environmental
adaptation
allow
us
understand
chemical
diversity
composition
Many
herbs’
phytochemical
constituents
health
benefits
not
fully
explored.
Given
large
global
distribution
as
well
impacts
growth
duration
factors
phytochemicals
it
crucial
emphasize
needs
using
technologies
address
basic
applied
problems
aid
developing
new
improved
plant
discovering
ingredients.
Chinese Herbal Medicines,
Год журнала:
2024,
Номер
16(2), С. 180 - 189
Опубликована: Фев. 24, 2024
Rhizosphere
microorganisms,
as
one
of
the
most
important
components
soil
microbiota
and
plant
holobiont,
play
a
key
role
in
medicinal
plant-soil
ecosystem,
which
are
closely
related
to
growth,
adaptability,
nutrient
absorption,
stress
tolerance
pathogen
resistance
host
plants.
In
recent
years,
with
wide
application
molecular
biology
omics
technologies,
outcomes
rhizosphere
microorganisms
on
health,
biomass
production
secondary
metabolite
biosynthesis
plants
have
received
extensive
attention.
However,
whether
or
what
extent
can
contribute
construction
quality
evaluation
system
Chinese
materials
is
still
elusive.
Based
significant
microbes
survival
formation
plants,
this
paper
proposed
new
concept
microbial
markers
(micro-markers),
expounded
relevant
research
methods
ideas
applying
concept,
highlighted
importance
micro-markers
control
traditional
medicines
(TCMs),
introduced
potential
value
environmental
assessment,
pest
assessment
TCMs.
It
provides
reference
for
developing
ecological
planting
TCMs
ensuring
high
by
regulating
communities.
SABRAO Journal of Breeding and Genetics,
Год журнала:
2024,
Номер
56(1), С. 45 - 53
Опубликована: Фев. 29, 2024
An
increased
intensity
of
agricultural
mineral
fertilizers'
use
to
raise
crop
yields
has
disrupted
the
soil's
natural
balance.Researchers
worldwide
continually
analyze
biological
factors
in
farming
systems
as
a
transitional
stage
organic
increase
soil
fertility.The
presented
study
pursued
evaluating
effect
products
on
yield
and
quality
indicators
chickpeas
continental
climate
Kostanay
Region,
Republic
Kazakhstan.In
this
study,
chickpea
(Cicer
arietinum
L.)
cultivar
Yubileinyi,
sown
with
four
variants,
used
various
preparations
control
(pure
sowing).The
plant
samples'
analysis
ensued
laboratory
State
Institution
Republican
Scientific
Methodological
Center
Agrochemical
Service,
field
experiments
established
Zarechnoye
Agricultural
Experimental
Station
Limited
Liability
Partnership.The
object
was
cultivar.During
probe
period,
experimental
site
had
characteristic,
meteorological
conditions
were
arid,
hydrothermal
coefficient
1.0.Based
experiment
variants
preparations,
grain
ranged
from
8,740
13,699
kg
ha
-1
compared
treatment
(7,980
).The
chickpea's
also
showed
improvements,
grains
harvested
one
hectare
contained
245.6
protein
62.4
carbohydrates.The
significant
improvement
due
active
substances
different
during
study.
Abstract
Background
Bletilla
striata
(Thunb.)
Reichb.
f.
(
B.
)
is
a
perennial
herbaceous
plant
in
the
Orchidaceae
family
known
for
its
diverse
pharmacological
activities,
such
as
promoting
wound
healing,
hemostasis,
anti-inflammatory
effects,
antioxidant
properties,
and
immune
regulation.
Nevertheless,
microbe-plant-metabolite
regulation
patterns
remain
largely
undetermined,
especially
field
of
rhizosphere
microbes.
To
elucidate
interrelationships
between
soil
physics
chemistry
microbes
metabolites,
comprehensive
approach
combining
metagenome
analysis
targeted
metabolomics
was
employed
to
investigate
tubers
from
four
provinces
eight
production
areas
China.
Results
Our
study
reveals
that
core
microbiome
predominantly
comprised
Paraburkholderia
,
Methylibium
Bradyrhizobium
Chitinophaga
Mycobacterium
.
These
microbial
species
are
recognized
potentially
beneficial
plants
health.
Comprehensive
revealed
significant
association
accumulation
militarine
polysaccharides
composition
at
genus
level.
Furthermore,
we
found
environment
indirectly
influenced
metabolite
profile
by
affecting
Notably,
our
research
identifies
organic
carbon
primary
driving
factor
influencing
Conclusion
fndings
contribute
an
enhanced
understanding
regulatory
mechanism
involving
interactions.
This
provides
theoretical
basis
cultivation
high-quality
traditional
Chinese
medicine
striata.
