Tracing conflict-induced cognitive-control adjustments over time using aperiodic EEG activity
Cerebral Cortex,
Год журнала:
2024,
Номер
34(5)
Опубликована: Апрель 20, 2024
Cognitive-control
theories
assume
that
the
experience
of
response
conflict
can
trigger
control
adjustments.
However,
while
some
approaches
focus
on
adjustments
impact
selection
present
(in
trial
N),
other
in
next
upcoming
(N
+
1).
We
aimed
to
trace
over
time
by
quantifying
cortical
noise
means
fitting
oscillations
and
one
f
algorithm,
a
measure
aperiodic
activity.
As
predicted,
trials
increased
exponent
large
sample
171
healthy
adults,
thus
indicating
reduction.
While
this
adjustment
was
visible
N
already,
it
did
not
affect
before
trial.
This
suggests
do
ongoing
response-selection
processes
but
prepare
system
for
tighter
interpret
findings
terms
conflict-induced
switch
from
metacontrol
flexibility
persistence,
accompanied
or
even
implemented
reduction
noise.
Язык: Английский
Catecholaminergic Modulation of Metacontrol is Reflected by Changes in Aperiodic EEG Activity
The International Journal of Neuropsychopharmacology,
Год журнала:
2024,
Номер
27(8)
Опубликована: Авг. 1, 2024
Abstract
Background
“Metacontrol”
describes
the
ability
to
maintain
an
optimal
balance
between
cognitive
control
styles
that
are
either
more
persistent
or
flexible.
Recent
studies
have
shown
a
link
metacontrol
and
aperiodic
EEG
patterns.
The
present
study
aimed
gain
insight
into
neurobiological
underpinnings
of
by
using
methylphenidate
(MPH),
compound
known
increase
postsynaptic
catecholamine
levels
modulate
cortical
noise.
Methods
In
double-blind,
randomized,
placebo-controlled
design,
we
investigated
effect
MPH
(0.5
mg/kg)
on
activity
during
flanker
task
in
sample
n
=
25
neurotypical
adults.
To
quantify
noise,
employed
fitting
oscillations
one
over
f
algorithm.
Results
Compared
with
placebo,
increased
exponent,
suggesting
it
reduces
noise
2
ways.
First,
did
so
state-like
fashion,
as
main
drug
was
visible
significant
both
pre-trial
within-trial
periods.
Second,
electrode-specific
analyses
showed
also
affects
specific
processes
dampening
downregulation
conditions
requiring
control.
Conclusions
Our
findings
suggest
exponent
provides
neural
marker
states
changes
therein.
Further,
propose
effectiveness
medications
targeting
catecholaminergic
signaling
can
be
evaluated
studying
fostering
idea
quantification
indicator
pharmacological
treatment.
Язык: Английский
Aperiodic neural activity reflects metacontrol in task-switching
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Окт. 15, 2024
"Metacontrol"
refers
to
the
ability
find
right
balance
between
more
persistent
and
flexible
cognitive
control
styles,
depending
on
task
demands.
Recent
research
tasks
involving
response
conflict
regulation
indicates
a
consistent
link
aperiodic
EEG
activity
conditions
that
demand
or
less
style.
In
this
study,
we
explored
whether
connection
metacontrol
also
applies
flexibility.
We
examined
behavioral
data
from
two
separate
samples
engaged
in
task-switching
paradigm,
allowing
for
an
internal
replication
of
our
findings.
Both
studies
revealed
significantly
decreased
during
switching
compared
repetition.
Our
results
support
predictions
theory
but
contradict
those
traditional
theories
which
would
have
predicted
opposite
pattern
results.
propose
observed
signals
serves
as
valid
indicator
dynamic
neuroplasticity
metacontrol,
suggesting
truly
adaptive
does
not
necessarily
bias
processing
towards
persistence
every
challenge,
chooses
flexibility
biases
nature
challenge.
Язык: Английский
Catecholaminergic Modulation of Metacontrol Is Reflected in Aperiodic EEG Activity and Predicted by Baseline GABA+ and Glx Concentrations
Human Brain Mapping,
Год журнала:
2025,
Номер
46(4)
Опубликована: Март 1, 2025
The
ability
to
balance
between
being
persistent
versus
flexible
during
cognitive
control
is
referred
as
"metacontrol"
and
reflected
in
the
exponent
of
aperiodic
neural
activity.
Theoretical
considerations
suggest
that
metacontrol
affected
by
interplay
GABAergic,
glutamatergic,
catecholaminergic
systems.
Moreover,
evidence
suggests
fronto-striatal
structures
play
an
important
role.
Yet,
nexus
neurobiochemistry
structural
neuroanatomy
when
it
comes
foundations
not
understood.
To
examine
this,
we
investigated
how
experimental
manipulation
signaling
via
methylphenidate
(MHP)
baseline
levels
GABA
glutamate
anterior
cingulate
cortex
(ACC),
supplementary
motor
area
(SMA),
striatum
assessed
MR
spectroscopy
altered
task
performance
associated
activity
(assessed
EEG)
a
conflict
monitoring
task.
We
N
=
101
healthy
young
adults.
show
EEG-aperiodic
was
elevated
performance,
well
cognitively
challenging
conditions
requiring
more
processing
further
enhanced
MPH
administration.
Correlation
analyses
also
provided
for
role
individual
characteristics
dispositions
observed
GABA+
Glx
ACC,
SMA,
striatum.
Our
observations
point
catecholamines
amino
acid
neurotransmitter-driven
regulation
task-specific
(changes
in)
biases.
results
GABA/Glx
system
prefrontal-basal
ganglia
crucial
metacontrol.
Язык: Английский
Transcranial Direct Current Stimulation and Methylphenidate interact to increase Cognitive Persistence as a Core Component of Metacontrol: Evidence from aperiodic activity analyses
Brain stimulation,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
Metacontrol
is
the
ability
to
optimize
balance
between
cognitive
persistence
and
flexibility.
Recent
research
points
aperiodic
EEG
activity
as
a
neurophysiological
marker
for
metacontrol
its
modulations.
However,
causal
link
still
unclear.
We
provide
mechanistic
insights
into
neurobiological
foundations
of
means
enhance
it.
evaluated
interplay
anodal
transcranial
direct
current
stimulation
(atDCS)
Methylphenidate
(MPH),
both
which
are
known
alter
cortical
noise,
factor
that
can
be
measured
by
exponents
derived
from
data.
examined
impact
right
inferior
frontal
(midpoint
electrodes
FC4
F8)
20
minutes
offline
atDCS
at
2-mA
MPH
administration,
separately
combined,
on
while
healthy
adult
participants
(N=98)
performed
Go/NoGo
task.
used
FOOOF
(fitting
oscillations
&
one
over
f)
algorithm
examine
activity.
obtained
an
interaction
indicating
effective
in
reducing
neural
(i.e.,
increased
exponents)
when
being
combined
with
administration.
Aperiodic
modulated
through
pharmacology-tuned
atDCS.
rely
overlapping
mechanisms.
depending
atDCS-MPH
stimulation.
Hence,
suitable
tools
achieve
exogenous
modulation
bias
indices
demonstrate
effectiveness
such
tools.
Язык: Английский
Code conflict in an event file task is reflected by aperiodic neural activity
Neuroreport,
Год журнала:
2025,
Номер
36(7), С. 337 - 341
Опубликована: Апрель 9, 2025
We
investigated
the
relationship
between
aperiodic
electroencephalography
(EEG)
activity
and
code
conflict,
hypothesizing
that
former
might
serve
as
an
indicator
of
latter.
analyzed
EEG
behavioral
outcomes
a
sample
performing
event
file
task,
which
assesses
conflict
in
co-occurring
or
temporally
overlapping
stimulus
response
features.
To
quantify
activity,
we
employed
fitting
oscillations
&
one-over-f
algorithm.
The
results
revealed
typical
partial-repetition
cost
effect,
indicating
performance
is
impaired
if
repeats
while
alternates,
vice
versa.
This
suggests
previously
combined
shape
were
stored
retrieved
when
any
one
these
components
was
repeated.
Notably,
this
effect
also
evident
exponent,
lower
for
partial
repetitions
than
full
alternations,
implying
increased
cortical
noise,
higher
excitatory
E
/
I
ratio,
noisier
decision-making
processes.
scalp
distribution
aligns
with
its
sensorimotor
characteristics.
Thus,
interpret
findings
promising
preliminary
evidence
exponent
may
valuable
neural
marker
conflict.
Язык: Английский
Metacontrol-related aperiodic neural activity decreases but strategic adjustment thereof increases from childhood to adulthood
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Май 26, 2025
Язык: Английский
Neurophysiological Dynamics of Metacontrol States: EEG Insights into Conflict Regulation
NeuroImage,
Год журнала:
2024,
Номер
302, С. 120915 - 120915
Опубликована: Ноя. 1, 2024
Understanding
the
neural
mechanisms
underlying
metacontrol
and
conflict
regulation
is
crucial
for
insights
into
cognitive
flexibility
persistence.
This
study
employed
electroencephalography
(EEG),
EEG-beamforming
directed
connectivity
analyses
to
explore
how
varying
states
influence
at
a
neurophysiological
level.
Metacontrol
were
manipulated
by
altering
frequency
of
congruent
incongruent
trials
across
experimental
blocks
in
modified
flanker
task,
both
behavioral
electrophysiological
measures
analyzed.
Behavioral
data
confirmed
manipulation's
efficacy,
showing
an
increase
persistence
bias
reduction
during
increased
regulation.
Electrophysiologically,
theta
band
activity
paralleled
data,
suggesting
that
oscillations
reflect
mismatch
between
expected
actual
task
demands.
Alpha
beta
dynamics
differed
blocks,
though
these
changes
did
not
directly
mirror
effects.
Post-response
alpha
more
pronounced
persistence-biased
states,
indicating
reset
mechanism
preparing
future
By
using
novel
artificial
networks
method,
revealed
enhanced
inter-regional
communication
stronger
top-down
control
sensorimotor
integration.
Overall,
was
closely
tied
processes,
while
bands
played
role
resetting
system
upcoming
tasks.
These
findings
provide
deeper
understanding
substrates
involved
monitoring,
emphasizing
distinct
roles
different
processes.
Язык: Английский
The development of aperiodic neural activity in the human brain
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 9, 2024
The
neurophysiological
mechanisms
supporting
brain
maturation
are
fundamental
to
attention
and
memory
capacity
across
the
lifespan.
Human
regions
develop
at
different
rates,
with
many
developing
into
third
fourth
decades
of
life.
Here,
in
this
preregistered
study
(https://osf.io/gsru7),
we
analyzed
intracranial
EEG
(iEEG)
recordings
from
widespread
a
large
developmental
cohort.
Using
task-based
(i.e.,
to-be-remembered
visual
stimuli)
task-free
(resting-state)
data
101
children
adults
(5.93
-
54.00
years,
63
males;
Язык: Английский