Genetics and Genomics of Infectious Diseases in Key Aquaculture Species DOI Open Access
Nguyen Hong Nguyen

Опубликована: Дек. 6, 2023

Diseases pose a significant and pressing concern for the sustainable development of aquaculture sector, particularly as their impact continues to grow due climatic shifts such rising water temperatures. While various approaches, ranging from biosecurity measures vaccines, have been devised combat infectious diseases, efficacy is disease- species-specific contingent upon multitude factors. The field genetics genomics offer effective tools control prevent disease outbreaks in aquatic animal species. In this study, we present key findings our recent research, focusing on genetic resistance three specific diseases: White Spot Syndrome Virus WSSV) white shrimp, Bacterial Necrotic Pancreatitis (BNP) striped catfish skin fluke (a parasitic ailment) yellowtail kingfish. Our investigations reveal that all species possess substantial heritable components resistant traits, indicating potential responsiveness artificial selection improvement programs tailored these diseases. Also, observed high association between traits survival rates. Through selective breeding aimed at enhancing pathogens, achieved gains, averaging 10% per generation. These also contributed positively overall production performance productivity Although effects immunological or immune responses were not they yielded favourable results catfish. Furthermore, genomic analyses, including shallow genome sequencing pedigreed populations, enriched understanding architecture underlying traits. are primarily governed by polygenic nature, with numerous genes variants, each small effects. Leveraging range advanced statistical methods, mixed models machine deep learning, developed prediction demonstrated moderate levels accuracy forecasting disease-related addition genomics, RNA-seq experiments identified several undergo upregulation response infection viral loads within populations. Preliminary microbiome data, while offering limited predictive one studied species, underscore combining data sequence information enhance power Lastly, paper briefly discusses roles precision agriculture systems, AI algorithms, outlines path future research expedite disease-resistant lines target conclusion, study underscores critical role fortifying sector against threats posed paving way more resilient development.

Язык: Английский

Chromosome-level genome assembly of the sea cucumber Apostichopus japonicus DOI Creative Commons

Lina Sun,

Chunxi Jiang,

Fang Su

и другие.

Scientific Data, Год журнала: 2023, Номер 10(1)

Опубликована: Июль 13, 2023

Abstract Sea cucumber is a morphologically diverse and ecologically important clade of echinoderms. The sea Apostichopus japonicus the most economically valuable species cucumber. initial assembly A. genome was released in 2017. However, this fragmented lacks relative position information genes on chromosomes. In study, we produced high-quality chromosome-level using Pacbio HiFi long-reads Hi-C sequencing data. assembled spanned 671.60 Mb with contig N50 size 17.20 scaffold 29.65 Mb. A total 99.9% anchored to 23 total, 19,828 were annotated, 97.2% BUSCO fully represented. This will not only aid development sustainable aquaculture practices, but also lay foundation for deeper understanding their genetic makeup, evolutionary history, ecological adaptation.

Язык: Английский

Процитировано

25

Genetics and Genomics of Infectious Diseases in Key Aquaculture Species DOI Creative Commons
Nguyen Hong Nguyen

Biology, Год журнала: 2024, Номер 13(1), С. 29 - 29

Опубликована: Янв. 4, 2024

Diseases pose a significant and pressing concern for the sustainable development of aquaculture sector, particularly as their impact continues to grow due climatic shifts such rising water temperatures. While various approaches, ranging from biosecurity measures vaccines, have been devised combat infectious diseases, efficacy is disease species specific contingent upon multitude factors. The fields genetics genomics offer effective tools control prevent outbreaks in aquatic animal species. In this study, we present key findings our recent research, focusing on genetic resistance three diseases: White Spot Syndrome Virus (WSSV) white shrimp, Bacterial Necrotic Pancreatitis (BNP) striped catfish, skin fluke (a parasitic ailment) yellowtail kingfish. Our investigations reveal that all possess substantial heritable components disease-resistant traits, indicating potential responsiveness artificial selection improvement programs tailored these diseases. Also, observed high association between traits survival rates. Through selective breeding aimed at enhancing pathogens, achieved gains, averaging 10% per generation. These also contributed positively overall production performance productivity Although effects immunological or immune responses were not they yielded favorable results catfish. Furthermore, genomic analyses, including shallow genome sequencing pedigreed populations, enriched understanding architecture underlying traits. are primarily governed by polygenic nature, with numerous genes variants, each small effects. Leveraging range advanced statistical methods, mixed models machine deep learning, developed prediction demonstrated moderate-to-high levels accuracy forecasting disease-related addition genomics, RNA-seq experiments identified several undergo upregulation response infection viral loads within populations. Preliminary microbiome data, while offering limited predictive one studied species, underscore combining data sequence information enhance power Lastly, paper briefly discusses roles precision agriculture systems AI algorithms outlines path future research expedite lines target conclusion, study underscores critical role fortifying sector against threats posed paving way more resilient development.

Язык: Английский

Процитировано

7

Molecular mechanisms of sex determination and differentiation in decapod crustaceans for potential aquaculture applications: An overview DOI
Tao Wang, Yang Yu, Shihao Li

и другие.

Reviews in Aquaculture, Год журнала: 2024, Номер 16(4), С. 1819 - 1839

Опубликована: Май 23, 2024

Abstract Crustacean aquaculture, especially monosex culture, requires a comprehensive knowledge of the mechanisms regulating sex determination and differentiation. Decapod crustaceans display either female heterogamety (ZW/ZZ) or male (XY/XX) as their mode genotypic determination. However, some decapod species exhibit sexual plasticity via removing androgenic gland, knockdown insulin receptor transcripts, administrating exogenous steroids, altering environmental factors. Although master sex‐determining gene in decapods remains elusive, various genes, hormones, neurotransmitter are emerging important factors This review looks into recent advancements studies related to genetic system that trigger reversal. Moreover, elucidation role differentiation both females males, well underlying interrelated regulatory mechanisms, provides justification for three levels application: induction populations, detection precocious genotype, prevention uncontrolled reproduction. Finally, we proposed future directions bioinformatics analysis genome editing coupled with control increase yield economic decapods. In conclusion, this foundation research on reproductive biology regulation decapods, aim aiding practitioners advancing crustacean aquaculture industry.

Язык: Английский

Процитировано

7

CRUSTADB: An integrated genomics platform for crustaceans DOI
Qiong Wang, Jianjian Lv, Ping Liu

и другие.

The Innovation Life, Год журнала: 2025, Номер unknown, С. 100116 - 100116

Опубликована: Янв. 1, 2025

<p>Crustacea is a species-rich subphylum of Arthropoda that contains mostly aquatic species. Here, we established comprehensive genomic database dedicated to the Crustacea. CRUSTADB represents significant advancement in crustacean genomics, integrating an extensive array resources. The encompasses 33 latest genomes, providing foundational resource for genetic and studies within this clade. Additionally, it includes impressive 789 Gb resequencing data across 10 species order Decapoda, 297 transcriptomes from 28 diverse species, 312 mitochondrial offering broad spectrum information. not merely repository data; also offers suite user-friendly tools designed multifaceted integrative comparative analyses. These enable users visually browse genomes access wide range detailed information, including genome assembly statistics, variations, gene annotations, expression profiles, family dynamics, data. Thus, will facilitate understanding serving as invaluable researchers field. can be accessed at <ext-link ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://crustacean_ysfri.qnlm.ac/#/home">http://crustacean_ysfri.qnlm.ac/#/home</ext-link>.</p>

Язык: Английский

Процитировано

0

Construction of the Red Swamp Crayfish (Procambarus clarkii) Family Selection Population and Whole Genome Sequencing to Screen WIPFI Candidate Genes Related to Growth DOI Open Access
Xing Tian,

Xiudan Yuan,

Zhigang He

и другие.

Genes, Год журнала: 2025, Номер 16(2), С. 174 - 174

Опубликована: Янв. 31, 2025

Background/Objectives:Procambarus clarkii is an important freshwater aquaculture species in China which has the characteristics of rich nutrition and delicious taste. However, expansion scale, germplasm degradation, other problems that have become increasingly prominent seriously restrict sustainable development crayfish industry. Genetic improvement urgent need for industry, selective breeding way to improve varieties. Methods: We established full-sibling family populations red swamp performed whole-genome resequencing F3 family-selected population wild from four regions Hunan Province (Nanx, Mil, Caish, Wangc). Results: The results showed there was a clear separation between population, decline rate slightly faster than population. There local gene flow populations, as well families. In addition, 52 SNP loci related body weight traits were identified by genome-wide association analysis, candidate WIPF1 growth screened out. Conclusions: line selection obtained more stable lines. this study Wiskott-Aldrich syndrome protein-interacting protein member 1 (WIPF1) first time. provide theoretical basis exploring mechanism P. carrying out in-depth genetic improvement.

Язык: Английский

Процитировано

0

A brief and updated introduction to the neuroendocrine system of crustaceans DOI
Leonardo Airton Ressel Simões,

Rafaella Sanfelice Normann,

J. Sook Chung

и другие.

Molecular and Cellular Endocrinology, Год журнала: 2024, Номер 590, С. 112265 - 112265

Опубликована: Май 1, 2024

Язык: Английский

Процитировано

4

Molecular mechanisms of Mmd2 gene in regulating growth of the Pacific white shrimp Litopenaeus vannamei DOI Creative Commons
Shuqing Si, Xiaojun Zhang, Yang Yu

и другие.

Marine Life Science & Technology, Год журнала: 2025, Номер 7(1), С. 50 - 65

Опубликована: Фев. 15, 2025

Abstract Growth of the Pacific white shrimp Litopenaeus vannamei , most important farmed crustacean, has consistently been a focal point for breeders. Over past decades, some candidate genes growth have identified. However, further research is needed to elucidate molecular regulatory mechanism these genes. LvMmd2 was previously identified as gene that may inhibit L. . In this study, we analyzed genotype and expression in breeding family indicated its role growth-inhibiting gene. We found co-localized with homolog LvPAQR3 at Golgi apparatus. Using co-immunoprecipitation (Co-IP) DUAL membrane system yeast two-hybrid (MbY2H), interactions between LvPAQR3, LvRaf1, well LvRho. These results suggest directly indirectly regulates Ras signaling pathway. Furthermore, show affect PI3K/AKT, insulin, Hippo pathways regulate cell proliferation differentiation via LvRaf1. Through transcriptome MbY2H analyses, also revealed interaction proteins involved growth, immunity, protein transport, synthesis, modification. findings demonstrate various through which growth. This study provides insights into regulated by Mmd2 enhances our understanding function, highlights potential application breeding.

Язык: Английский

Процитировано

0

Antidepressants – The new endocrine disruptors? The case of crustaceans DOI
Thomas Knigge

Molecular and Cellular Endocrinology, Год журнала: 2024, Номер 583, С. 112155 - 112155

Опубликована: Янв. 6, 2024

Язык: Английский

Процитировано

3

Advancing Aquaculture Sustainability: A Comprehensive Review of Biofloc Technology Trends, Innovative Research Approaches, and Future Prospects DOI
Gang Liu, M.C.J. Verdegem, Zhangying Ye

и другие.

Reviews in Aquaculture, Год журнала: 2024, Номер unknown

Опубликована: Сен. 17, 2024

ABSTRACT Biofloc technology (BFT), initially adapted for shrimp farming in the 1970s, represents a sophisticated ecosystem of microorganisms designed to enhance aquaculture productivity and sustainability. Despite its established history, research into BFT is surprisingly still at an early stage globally. This review conducted bibliometric analysis 612 articles from major journals spanning 2008–2023 systematically explore development, trends, focal points research. The revealed that bulk significant contributions originates Brazil China, highlighting areas interest can be categorized four hotspots, such as (1) efficient nitrogen transformation, (2) biofloc microbiology, (3) biofloc's immunostimulant properties, (4) evaluation methodologies. At end, microecology concept was introduced, cross‐discipline methods were promoted field. Notably, much exploratory phase, with numerous functional bacteria unidentified optimization strategies underdeveloped. These gaps present opportunities enhancing through improvements wastewater management, product quality, safety, yield. Furthermore, notes growing trend applying microbiome microecological aquaculture, high‐throughput sequencing data increasingly used understand microbial interactions transformation within bioflocs. direction promises unlock further insights complex ecosystems bioflocs their applications sustainable aquaculture.

Язык: Английский

Процитировано

3

Integration of transcriptome and whole-genome re-sequencing analyses reveal growth-related candidate genes in Procambarus clarkii DOI

Zihao Zhou,

Yanhe Li, Yu‐Dong Shen

и другие.

Comparative Biochemistry and Physiology Part D Genomics and Proteomics, Год журнала: 2024, Номер 49, С. 101198 - 101198

Опубликована: Фев. 1, 2024

Язык: Английский

Процитировано

2