New Phytologist, Год журнала: 2025, Номер unknown

Опубликована: Май 30, 2025

Summary Flavones, a key group of flavonoids, play significant role in plant adaptation to ecological niches and are valuable medicinal resources. However, the genetic basis underlying their contribution remains largely unknown. Here, using metabolite‐based genome‐wide association study, we report that natural variation flavone contents Chrysanthemum indicum , wild chrysanthemum herb, is mainly determined by recently duplicated synthase II gene CiFNSII‐1.2 . Enzymatic assays molecular dynamics simulations reveal amino acid residues 246 th 261 confer higher enzymatic activity compared with its ancestral form. These act as critical modulators, regulating flexibility external entrance contributing enzyme's improved functionality. Transgenic evaluation demonstrate contributes accumulation drought adaptation. Our findings provide insights into biochemical evolutionary flavones facilitating drought‐prone habitats chrysanthemum.

Язык: Английский