Functional Characterization of 5-O-Glycosyltranferase Transforming 3-O Anthocyanins into 3,5-O Anthocyanins in Freesia hybrida DOI Open Access

Adnan Adnan,

Tingting Bao, Xiang Zheng

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(10), С. 4542 - 4542

Опубликована: Май 9, 2025

Floral coloration in Freesia hybrida is predominantly attributed to anthocyanins, with glycosylation playing a critical role their stability and diversity. This study investigates the molecular mechanisms underlying color variation between F. cultivars, focusing on anthocyanin 5-O-glucosyltransferases (An5GTs). HPLC analysis revealed that ‘Pink Passion’ petals accumulate 3,5-O-diglucosidic absent ‘Red River®’ ‘Ambiance’. RNA-seq identified seven candidate Fh5GT genes, phylogenetic subcellular localization analyses confirming classification as cytosolic glycosyltransferases. Expression profiling highlighted elevated transcript levels of Fh5GT1, Fh5GT3, Fh5GT7 Passion’, correlating its di-glucosidic accumulation. In vitro enzymatic assays demonstrated Fh5GT3 preferentially glucosylate 3-O-monoglucosidic anthocyanins form stable 3,5-O-diglucosides, minimal activity anthocyanidins generate 5-O-glucosidic anthocyanins. Heterologous expression Arabidopsis complemented deficiency 5gt mutants, restoring pigmentation. These findings elucidate potential 5GTs modulating floral diversity through modification, providing insights for targeted breeding strategies enhance ornamental traits horticultural species.

Язык: Английский

A Comprehensive Review of Plant Volatile Terpenoids, Elucidating Interactions with Surroundings, Systematic Synthesis, Regulation, and Targeted Engineering Production DOI Creative Commons
Wei Jin, Zhongzhou Yang, Kedong Xu

и другие.

Biology, Год журнала: 2025, Номер 14(5), С. 466 - 466

Опубликована: Апрель 25, 2025

Plants require a flexible avoidance mechanism as they need to cope with external stimuli and challenges through complex specialized metabolites, among which volatile terpenoids make outstanding contributions, acting key media signal substances in the cooperation between plants surrounding organisms. In recent decades, research on identification functional characterization of terpenoid synthase factors regulating metabolic shunts has gained significant attention, leading substantial progress notable achievements. However, popularization insect disease prevention, medical care, cosmetics, other fields, coupled increasing resistance artificially produced chemical products, demand for natural outpaced supply, prompting emergence popularity targeted engineering mass production using microorganisms platforms. this paper, we provide detailed overview knowledge regard multiple functions, synthetic pathways, genes, related regulatory factors, target engineering.

Язык: Английский

Процитировано

0

Functional Characterization of 5-O-Glycosyltranferase Transforming 3-O Anthocyanins into 3,5-O Anthocyanins in Freesia hybrida DOI Open Access

Adnan Adnan,

Tingting Bao, Xiang Zheng

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(10), С. 4542 - 4542

Опубликована: Май 9, 2025

Floral coloration in Freesia hybrida is predominantly attributed to anthocyanins, with glycosylation playing a critical role their stability and diversity. This study investigates the molecular mechanisms underlying color variation between F. cultivars, focusing on anthocyanin 5-O-glucosyltransferases (An5GTs). HPLC analysis revealed that ‘Pink Passion’ petals accumulate 3,5-O-diglucosidic absent ‘Red River®’ ‘Ambiance’. RNA-seq identified seven candidate Fh5GT genes, phylogenetic subcellular localization analyses confirming classification as cytosolic glycosyltransferases. Expression profiling highlighted elevated transcript levels of Fh5GT1, Fh5GT3, Fh5GT7 Passion’, correlating its di-glucosidic accumulation. In vitro enzymatic assays demonstrated Fh5GT3 preferentially glucosylate 3-O-monoglucosidic anthocyanins form stable 3,5-O-diglucosides, minimal activity anthocyanidins generate 5-O-glucosidic anthocyanins. Heterologous expression Arabidopsis complemented deficiency 5gt mutants, restoring pigmentation. These findings elucidate potential 5GTs modulating floral diversity through modification, providing insights for targeted breeding strategies enhance ornamental traits horticultural species.

Язык: Английский

Процитировано

0