bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июнь 27, 2023
Abstract
The
integrative
response
to
exercise
differs
between
sexes,
with
oxidative
energy
contribution
purported
as
a
potential
mechanism.
present
study
investigated
whether
this
difference
was
evident
in
the
kinetics
of
oxygen
uptake
(V□O
2
)
and
extraction
(HHb+Mb)
during
exercise.
Sixteen
adults
(8
males,
8
females,
age:
27±5
years)
completed
three
experimental
visits.
Incremental
testing
performed
obtain
lactate
threshold
V□O
2peak
.
Subsequent
visits
involved
six-minute
cycling
bouts
at
80%
one
30-minute
bout
work
rate
30%
power
Pulmonary
gas
exchange
near-infrared
spectroscopy
vastus
lateralis
were
used
continuously
sample
HHb+Mb,
respectively.
phase
II
quantified
using
mono-exponential
curves
moderate
heavy
Slow
component
amplitudes
also
for
intensity
domain.
Relative
values
not
different
sexes
(
p
=0.111).
Males
achieved
∼30%
greater
outputs
=0.002).
In
domains,
relative
amplitude
transition
(∼24
∼40%
,
≥0.179)
HHb+Mb
(∼20
∼32%
ischemia,
≥0.193).
Similarly,
there
no
sex
differences
time
constants
(∼28
s,
≥0.385)
or
(∼10s,
≥0.274).
domain,
neither
≥0.686)
≥0.432)
slow
sexes.
did
differ
males
suggesting
similar
dynamic
responses
metabolism
intensity-matched
New
Noteworthy
This
demonstrated
change
deoxyhaemoglobin
modelled
curve
fitting,
which
revealed
provision
provides
insight
into
previously
reported
Experimental Physiology,
Год журнала:
2024,
Номер
109(8), С. 1317 - 1329
Опубликована: Июнь 18, 2024
Abstract
Emerging
questions
in
neuromuscular
physiology
revolve
around
whether
males
and
females
share
similar
neural
control
diverse
tasks
across
a
broad
range
of
intensities.
In
order
to
explore
these
features,
high‐density
electromyography
was
used
record
the
myoelectrical
activity
biceps
brachii
during
trapezoidal
isometric
contractions
at
35%
70%
maximal
voluntary
force
(MVF)
on
11
male
13
female
participants.
Identified
motor
units
were
then
classified
as
lower‐threshold
(recruited
≤30%MVF)
higher‐threshold
>30%MVF).
The
discharge
rate,
interspike
interval
variability,
recruitment
derecruitment
thresholds,
estimates
drive
neurons
assessed.
Female
showed
higher
(
P
<
0.001),
accompanied
by
rate
=
0.006),
plateau
0.001)
0.001).
On
other
hand,
greater
0.04),
0.005),
0.04)
0.01).
Motor
unit
normalised
threshold
significantly
while
no
differences
observed
units.
Recruitment
thresholds
are
all
intensities
However,
have
activation
deactivation
strategies,
evidenced
recruitment‐to‐derecruitment
ratios
>
0.05).
This
study
encompasses
intensity
analyse
sex‐related
differences,
highlighting
rates
units,
elevated
males,
convergences
strategies.
Highlights
What
is
central
question
study?
Do
behave
similarly
low‐
high‐intensity
contractions?
main
finding
its
importance?
show
low‐intensity
lower
tasks,
with
behaviour.
A
broader
inter‐spike
variability
also
females.
These
findings
underline
that
there
sex‐specific
concern
firing
strategies
based
task
intensity.
Experimental Physiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 26, 2025
The
effect
of
biological
sex
on
rates
skeletal
muscle
mitochondrial
respiration
supported
by
creatine-dependent
phosphate
shuttling
was
previously
unknown.
aim
this
investigation
to
test
the
hypothesis
that
females
and
males
matched
for
peak
oxygen
uptake
normalized
fat-free
mass
would
not
exhibit
differences
in
mass-specific
intrinsic
presence
or
absence
creatine.
Rates
complex
I
(pyruvate
malate)-
I+II-supported,
adenosine
diphosphate
(ADP)-stimulated
20
mM
creatine
were
measured
via
high-resolution
respirometry.
Total,
intermyofibrillar
subsarcolemmal
volume
density
analysed
using
transmission
electron
microscopy.
obtained
normalizing
total
transport
chain
subunit
protein
content.
Overall,
there
no
There
also
total,
Our
data
demonstrate
an
overall
lack
sex-based
I-
ADP-stimulated
aerobic
fitness.
Thus,
per
se
does
appear
modulate
healthy
young
adults.
Journal of Applied Physiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 11, 2024
The
integrative
response
to
exercise
differs
between
sexes,
with
oxidative
energy
contribution
purported
as
a
potential
mechanism.
present
study
investigated
whether
this
difference
was
evident
in
the
kinetics
of
oxygen
uptake
(V̇o
Scandinavian Journal of Medicine and Science in Sports,
Год журнала:
2024,
Номер
34(7)
Опубликована: Июль 1, 2024
ABSTRACT
Few
studies
have
explored
the
kinetics
of
performance
and
perceived
fatigability
during
high‐intensity
interval
training,
despite
its
popularity.
We
aimed
to
characterize
recovery
an
8
×
4‐min
HIIT
protocol,
hypothesizing
that
most
muscle
function
impairment
would
occur
initial
four
intervals.
Fifteen
healthy
males
females
(mean
±
standard
deviation;
age
=
26
5
years,
V̇
O
2
max
46.8
6.1
mL·kg
−1
·min
)
completed
eight,
intervals
at
105%
critical
power
with
3
min
rest.
Maximal
voluntary
knee
extension
contractions
(MVCs)
coupled
electrical
nerve
stimulation
were
performed
baseline
after
first,
fourth,
eighth
MVC,
potentiated
twitch
force
(Pt),
Db10:100
ratio
all
declined
throughout
(
p
<
0.05).
MVC
sharply
1
(−15
9%
relative
baseline;
0.05)
had
only
further
(−26
11%;
0.05),
but
not
4
(−19
13%;
>
Pt
also
(Pt:
−18
13%,
Db10:100:
−14
20%;
−35
19%,
−30
−41
19%;
−32
18%;
Voluntary
activation
did
significantly
change
across
protocol
Evoked
was
blunted
as
more
completed:
1,
recovered
by
7
11%
compared
−6
7%
Ratings
effort,
fatigue,
leg
pain
rose
session
0.05
for
each)
greater
(effort
fatigue)
Otherwise,
exhibited
similar
kinetics,
contractile
declines
in
response
additional
Journal of Applied Physiology,
Год журнала:
2024,
Номер
137(1), С. 10 - 22
Опубликована: Май 23, 2024
Critical
power
(CP)
represents
an
important
threshold
for
exercise
performance
and
fatiguability.
We
sought
to
determine
the
extent
which
sex,
hemoglobin
mass
(Hb
Experimental Physiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 25, 2025
Abstract
This
study
aimed
to
evaluate
in
vivo
oxidative
capacity
and
relative
resistance
O
2
diffusion
using
near‐infrared
spectroscopy
(NIRS)
the
m.
triceps
brachii
of
recreational
world
class
swimmers
their
relationships
with
swimming
performance.
Twenty‐eight
were
enrolled
assigned
into
three
subgroups
according
level:
‘recreational/trained’
(Tier
1/2;
n
=
8),
‘national’
3;
12)
‘international/world
class’
4/5;
8).
Performance
was
evaluated
by
100
m
freestyle
trials.
Training
volume
measured
self‐reported
distance
(km/week).
The
recovery
k
non‐invasively
estimated
NIRS
through
repeated
intermittent
occlusions
under
two
conditions:
well‐oxygenated
(
HIGH
)
low
availability
LOW
).
difference
between
(Δ
calculated
as
an
index
diffusion.
FINA
points
performance
differed
among
all
groups.
greater
Tier
4/5
(34.0
±
5.5
km
week
−1
3
(35.5
11.6
than
1/2
(6.4
1.8
(3.18
0.41
2.79
0.40
min
versus
(2.10
0.36
;
P
<
0.002).
correlated
points,
training
volume.
∆
not
different
tiers
associated
or
M.
positively
swimmers.
,
which
reflects
diffusion,
athletes.
These
data
suggest
that
is
muscle
diffusing
exerts
a
similar
diffusive
flow
across
Journal of Applied Physiology,
Год журнала:
2023,
Номер
136(2), С. 298 - 312
Опубликована: Дек. 7, 2023
To
further
refine
the
near-infrared
spectroscopy
(NIRS)-derived
measure
of
skeletal
muscle
oxidative
capacity
in
humans,
we
sought
to
determine
whether
exercise
stimulus
intensity
affected
τ
value
and/or
influenced
magnitude
correlations
with
vitro
measures
mitochondrial
content
and
vivo
indices
performance.
Males
(
AJP Regulatory Integrative and Comparative Physiology,
Год журнала:
2024,
Номер
327(2), С. R195 - R207
Опубликована: Июнь 6, 2024
We
sought
to
determine
the
effects
of
acute
simulated
altitude
on
maximal
lactate
steady
state
(MLSS)
and
physiological
responses
cycling
at
10
W
above
MLSS-associated
power
output
(PO)
(MLSS
