No sex differences in oxygen uptake or extraction kinetics in the moderate or heavy exercise intensity domains DOI Creative Commons

Maria Solleiro Pons,

Lina Bernert,

Emily Hume

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Июнь 27, 2023

Abstract The integrative response to exercise differs between sexes, with oxidative energy contribution purported as a potential mechanism. present study investigated whether this difference was evident in the kinetics of oxygen uptake (V□O 2 ) and extraction (HHb+Mb) during exercise. Sixteen adults (8 males, 8 females, age: 27±5 years) completed three experimental visits. Incremental testing performed obtain lactate threshold V□O 2peak . Subsequent visits involved six-minute cycling bouts at 80% one 30-minute bout work rate 30% power Pulmonary gas exchange near-infrared spectroscopy vastus lateralis were used continuously sample HHb+Mb, respectively. phase II quantified using mono-exponential curves moderate heavy Slow component amplitudes also for intensity domain. Relative values not different sexes ( p =0.111). Males achieved ∼30% greater outputs =0.002). In domains, relative amplitude transition (∼24 ∼40% , ≥0.179) HHb+Mb (∼20 ∼32% ischemia, ≥0.193). Similarly, there no sex differences time constants (∼28 s, ≥0.385) or (∼10s, ≥0.274). domain, neither ≥0.686) ≥0.432) slow sexes. did differ males suggesting similar dynamic responses metabolism intensity-matched New Noteworthy This demonstrated change deoxyhaemoglobin modelled curve fitting, which revealed provision provides insight into previously reported

Язык: Английский

Characterising sex‐related differences in lower‐ and higher‐threshold motor unit behaviour through high‐density surface electromyography DOI Creative Commons
Edoardo Lecce,

Alessandra Conti,

Stefano Nuccio

и другие.

Experimental Physiology, Год журнала: 2024, Номер 109(8), С. 1317 - 1329

Опубликована: Июнь 18, 2024

Abstract Emerging questions in neuromuscular physiology revolve around whether males and females share similar neural control diverse tasks across a broad range of intensities. In order to explore these features, high‐density electromyography was used record the myoelectrical activity biceps brachii during trapezoidal isometric contractions at 35% 70% maximal voluntary force (MVF) on 11 male 13 female participants. Identified motor units were then classified as lower‐threshold (recruited ≤30%MVF) higher‐threshold >30%MVF). The discharge rate, interspike interval variability, recruitment derecruitment thresholds, estimates drive neurons assessed. Female showed higher ( P < 0.001), accompanied by rate = 0.006), plateau 0.001) 0.001). On other hand, greater 0.04), 0.005), 0.04) 0.01). Motor unit normalised threshold significantly while no differences observed units. Recruitment thresholds are all intensities However, have activation deactivation strategies, evidenced recruitment‐to‐derecruitment ratios > 0.05). This study encompasses intensity analyse sex‐related differences, highlighting rates units, elevated males, convergences strategies. Highlights What is central question study? Do behave similarly low‐ high‐intensity contractions? main finding its importance? show low‐intensity lower tasks, with behaviour. A broader inter‐spike variability also females. These findings underline that there sex‐specific concern firing strategies based task intensity.

Язык: Английский

Процитировано

14

Biological sex does not impact intrinsic mitochondrial respiration supported by complexes I and II in human skeletal muscle DOI Creative Commons
Emily J. Ferguson, Lauren J Pacitti, J. P. Bureau

и другие.

Experimental Physiology, Год журнала: 2025, Номер unknown

Опубликована: Март 26, 2025

The effect of biological sex on rates skeletal muscle mitochondrial respiration supported by creatine-dependent phosphate shuttling was previously unknown. aim this investigation to test the hypothesis that females and males matched for peak oxygen uptake normalized fat-free mass would not exhibit differences in mass-specific intrinsic presence or absence creatine. Rates complex I (pyruvate malate)- I+II-supported, adenosine diphosphate (ADP)-stimulated 20 mM creatine were measured via high-resolution respirometry. Total, intermyofibrillar subsarcolemmal volume density analysed using transmission electron microscopy. obtained normalizing total transport chain subunit protein content. Overall, there no There also total, Our data demonstrate an overall lack sex-based I- ADP-stimulated aerobic fitness. Thus, per se does appear modulate healthy young adults.

Язык: Английский

Процитировано

1

No sex differences in oxygen uptake or extraction kinetics in the moderate or heavy exercise intensity domains DOI Creative Commons

Maria Solleiro Pons,

Lina Bernert,

Emily Hume

и другие.

Journal of Applied Physiology, Год журнала: 2024, Номер unknown

Опубликована: Янв. 11, 2024

The integrative response to exercise differs between sexes, with oxidative energy contribution purported as a potential mechanism. present study investigated whether this difference was evident in the kinetics of oxygen uptake (V̇o

Язык: Английский

Процитировано

4

The Effect of Duration on Performance and Perceived Fatigability During Acute High‐Intensity Interval Exercise in Young, Healthy Males and Females DOI Creative Commons
Thomas R. Tripp,

A.M. Caswell,

Saied Jalal Aboodarda

и другие.

Scandinavian Journal of Medicine and Science in Sports, Год журнала: 2024, Номер 34(7)

Опубликована: Июль 1, 2024

ABSTRACT Few studies have explored the kinetics of performance and perceived fatigability during high‐intensity interval training, despite its popularity. We aimed to characterize recovery an 8 × 4‐min HIIT protocol, hypothesizing that most muscle function impairment would occur initial four intervals. Fifteen healthy males females (mean ± standard deviation; age = 26 5 years, V̇ O 2 max 46.8 6.1 mL·kg −1 ·min ) completed eight, intervals at 105% critical power with 3 min rest. Maximal voluntary knee extension contractions (MVCs) coupled electrical nerve stimulation were performed baseline after first, fourth, eighth MVC, potentiated twitch force (Pt), Db10:100 ratio all declined throughout ( p < 0.05). MVC sharply 1 (−15 9% relative baseline; 0.05) had only further (−26 11%; 0.05), but not 4 (−19 13%; > Pt also (Pt: −18 13%, Db10:100: −14 20%; −35 19%, −30 −41 19%; −32 18%; Voluntary activation did significantly change across protocol Evoked was blunted as more completed: 1, recovered by 7 11% compared −6 7% Ratings effort, fatigue, leg pain rose session 0.05 for each) greater (effort fatigue) Otherwise, exhibited similar kinetics, contractile declines in response additional

Язык: Английский

Процитировано

4

The influence of sex, hemoglobin mass, and skeletal muscle characteristics on cycling critical power DOI

A.M. Caswell,

Thomas R. Tripp, Hilkka Kontro

и другие.

Journal of Applied Physiology, Год журнала: 2024, Номер 137(1), С. 10 - 22

Опубликована: Май 23, 2024

Critical power (CP) represents an important threshold for exercise performance and fatiguability. We sought to determine the extent which sex, hemoglobin mass (Hb

Язык: Английский

Процитировано

3

Oxidative and O2 diffusive function in triceps brachii of recreational to world class swimmers DOI Creative Commons

Simone Villanova,

Elisa Pastorio, Andrea Pilotto

и другие.

Experimental Physiology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 25, 2025

Abstract This study aimed to evaluate in vivo oxidative capacity and relative resistance O 2 diffusion using near‐infrared spectroscopy (NIRS) the m. triceps brachii of recreational world class swimmers their relationships with swimming performance. Twenty‐eight were enrolled assigned into three subgroups according level: ‘recreational/trained’ (Tier 1/2; n = 8), ‘national’ 3; 12) ‘international/world class’ 4/5; 8). Performance was evaluated by 100 m freestyle trials. Training volume measured self‐reported distance (km/week). The recovery k non‐invasively estimated NIRS through repeated intermittent occlusions under two conditions: well‐oxygenated ( HIGH ) low availability LOW ). difference between (Δ calculated as an index diffusion. FINA points performance differed among all groups. greater Tier 4/5 (34.0 ± 5.5 km week −1 3 (35.5 11.6 than 1/2 (6.4 1.8 (3.18 0.41 2.79 0.40 min versus (2.10 0.36 ; P < 0.002). correlated points, training volume. ∆ not different tiers associated or M. positively swimmers. , which reflects diffusion, athletes. These data suggest that is muscle diffusing exerts a similar diffusive flow across

Язык: Английский

Процитировано

0

Response: Fitness, endurance, and VO2max: Can men and women of same aerobic power be compared in critical-power-anchored HIIT performance? DOI
Lauren J Pacitti, Brendon J. Gurd

European Journal of Applied Physiology, Год журнала: 2025, Номер unknown

Опубликована: Май 20, 2025

Язык: Английский

Процитировано

0

Contraction intensity affects NIRS-derived skeletal muscle oxidative capacity but not its relationships to mitochondrial protein content or aerobic fitness DOI
Thomas R. Tripp,

Rachel M. McDougall,

Barnaby P. Frankish

и другие.

Journal of Applied Physiology, Год журнала: 2023, Номер 136(2), С. 298 - 312

Опубликована: Дек. 7, 2023

To further refine the near-infrared spectroscopy (NIRS)-derived measure of skeletal muscle oxidative capacity in humans, we sought to determine whether exercise stimulus intensity affected τ value and/or influenced magnitude correlations with vitro measures mitochondrial content and vivo indices performance. Males (

Язык: Английский

Процитировано

7

Sex differences in fatiguability during single-joint resistance exercise in a resistance-trained population DOI
Caleb C. Voskuil,

Monique D. Dudar,

Joshua C. Carr

и другие.

European Journal of Applied Physiology, Год журнала: 2024, Номер 124(8), С. 2261 - 2271

Опубликована: Март 5, 2024

Язык: Английский

Процитировано

1

Effects of acute simulated altitude on the maximal lactate steady state in humans DOI

Austin T. Beever,

Andrea Y. Zhuang,

Juan M. Murias

и другие.

AJP Regulatory Integrative and Comparative Physiology, Год журнала: 2024, Номер 327(2), С. R195 - R207

Опубликована: Июнь 6, 2024

We sought to determine the effects of acute simulated altitude on maximal lactate steady state (MLSS) and physiological responses cycling at 10 W above MLSS-associated power output (PO) (MLSS

Язык: Английский

Процитировано

1