HyperTRCSS: A hyperspectral time-resolved compressive sensing spectrometer for depth-sensitive monitoring of cytochrome-c-oxidase and blood oxygenation DOI Creative Commons
Natalie Li,

Seva Ioussoufovitch,

Mamadou Diop

и другие.

Journal of Biomedical Optics, Год журнала: 2024, Номер 29(01)

Опубликована: Янв. 24, 2024

SignificanceHyperspectral time-resolved (TR) near-infrared spectroscopy offers the potential to monitor cytochrome-c-oxidase (oxCCO) and blood oxygenation in adult brain with minimal scalp/skull contamination. We introduce a hyperspectral TR spectrometer that uses compressive sensing minimize acquisition time without compromising spectral range or resolution demonstrate oxCCO monitoring deep tissue.AimDevelop use it tissue.ApproachHomogeneous tissue-mimicking phantom experiments were conducted confirm spectrometer’s sensitivity oxygenation. Two-layer phantoms used evaluate bottom layer through 10 mm thick static top layer.ResultsThe was sensitive changes of two-layer phantoms, as confirmed by concomitant measurements acquired directly from layer. Measures highly correlated “gold standard” measures homogeneous experiments.ConclusionsThe results show is tissue

Язык: Английский

A review on time domain diffuse optics: principles and applications on human biological tissues DOI Creative Commons
Rebecca Re, Lorenzo Spinelli, Fabrizio Martelli

и другие.

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Апрель 9, 2025

Abstract The term diffusive media refers to all the for which photon diffusion equation provides an accurate description of light propagation. Indeed, this is case a plethora natural media, such as biological tissues and agricultural products, when illuminated by red near-infrared light. Diffuse Optics (DO) branch that studies how absorption scattering phenomena affect propagation in media. In review paper, we present introduction time domain (TD) DO, specific implementation DO employs picosecond pulses, fast sensitive photodetectors timing electronics record distribution time-of-flight (or path lengths) By interpreting TD signals with physical model provided theory, it possible estimate properties medium can be related physiological pathological conditions. We focus on principles building blocks instrumentation, applications targeting human (such brain, breast, muscle, others).

Язык: Английский

Процитировано

0

HyperTRCSS: A hyperspectral time-resolved compressive sensing spectrometer for depth-sensitive monitoring of cytochrome-c-oxidase and blood oxygenation DOI Creative Commons
Natalie Li,

Seva Ioussoufovitch,

Mamadou Diop

и другие.

Journal of Biomedical Optics, Год журнала: 2024, Номер 29(01)

Опубликована: Янв. 24, 2024

SignificanceHyperspectral time-resolved (TR) near-infrared spectroscopy offers the potential to monitor cytochrome-c-oxidase (oxCCO) and blood oxygenation in adult brain with minimal scalp/skull contamination. We introduce a hyperspectral TR spectrometer that uses compressive sensing minimize acquisition time without compromising spectral range or resolution demonstrate oxCCO monitoring deep tissue.AimDevelop use it tissue.ApproachHomogeneous tissue-mimicking phantom experiments were conducted confirm spectrometer’s sensitivity oxygenation. Two-layer phantoms used evaluate bottom layer through 10 mm thick static top layer.ResultsThe was sensitive changes of two-layer phantoms, as confirmed by concomitant measurements acquired directly from layer. Measures highly correlated “gold standard” measures homogeneous experiments.ConclusionsThe results show is tissue

Язык: Английский

Процитировано

2