An analysis framework for the integration of broadband NIRS and EEG to assess neurovascular and neurometabolic coupling

Scientific Reports, Год журнала: 2021, Номер 11(1)

Опубликована: Фев. 17, 2021

Abstract With the rapid growth of optical-based neuroimaging to explore human brain functioning, our research group has been developing broadband Near Infrared Spectroscopy (bNIRS) instruments, a technological extension functional (fNIRS). bNIRS unique capacity monitoring haemodynamics/oxygenation (measuring oxygenated and deoxygenated haemoglobin), metabolism changes in redox state cytochrome-c-oxidase). When combined with electroencephalography (EEG), provides neuromonitoring platform neurovascular coupling mechanisms. In this paper, we present novel pipeline for integrated analysis EEG signals, demonstrate its use on multi-channel data recorded concurrent healthy adults during visual stimulation task. We introduce Finite Impulse Response functions within General Linear Model show feasibility statistically localize haemodynamic metabolic activity occipital cortex. Moreover, results suggest that fusion measures unveils additional information functioning over imaging alone. The cross-correlation-based interrelationships between electrical (EEG) haemodynamic/metabolic revealed signal offers marker activity, being more closely coupled neuronal response.

Язык: Английский

---

Viewing neurovascular coupling through the lens of combined EEG–fNIRS: A systematic review of current methods

Psychophysiology, Год журнала: 2022, Номер 59(6)

Опубликована: Март 31, 2022

Abstract Neurovascular coupling is a key physiological mechanism that occurs in the healthy human brain, and understanding this process has implications for aging neuropsychiatric populations. Combined electroencephalography (EEG) functional near‐infrared spectroscopy (fNIRS) emerged as promising, noninvasive tool probing neurovascular interactions humans. However, utility of approach critically depends on methodological quality used multimodal integration. Despite growing number combined EEG–fNIRS applications reported recent years, rigor past studies remains unclear, limiting accurate interpretation findings hindering translational application approach. To fill knowledge gap, we evaluated various aspects previous performed individuals. A literature search was conducted using PubMed PsycINFO June 28, 2021. Studies involving concurrent EEG fNIRS measurements awake individuals were selected. After screening eligibility assessment, 96 included evaluation. Specifically, reviewed participant sampling, experimental design, signal acquisition, data preprocessing, outcome selection, analysis, results presentation these studies. Altogether, identified several notable strengths limitations existing literature. In light features EEG–fNIRS, recommendations are made to improve standardize research practices facilitate use when studying processes alterations among

Язык: Английский

---

Multimodal fNIRS-EEG Classification Using Deep Learning Algorithms for Brain-Computer Interfaces Purposes

Advances in intelligent systems and computing, Год журнала: 2019, Номер unknown, С. 209 - 220

Опубликована: Июнь 11, 2019

Язык: Английский

---

Differential pathlength factor in continuous wave functional near-infrared spectroscopy: reducing hemoglobin’s cross talk in high-density recordings

Neurophotonics, Год журнала: 2019, Номер 6(03), С. 1 - 1

Опубликована: Авг. 10, 2019

Functional near-infrared spectroscopy (fNIRS) estimates the functional oscillations of oxyhemoglobin and deoxyhemoglobin in cortex through scalp-located multiwavelength recordings. Hemoglobin are inferred temporal changes continuous-wave (CW) light attenuation. However, because diffusive multilayered head tissue structures, photon path is longer than source-detector separation, complicating hemoglobin evaluation. This aspect incorporated modified Beer-Lambert law where distance multiplied by differential pathlength factor (DPF). Since DPF estimation requires photons' time-of-flight information, assumed a priori CW-fNIRS. Importantly, errors spectrum induce cross talk, which detrimental for fNIRS. We propose to estimate subject-specific spectral dependence relying on multidistance high-density measurements. The procedure effective attenuation coefficient (EAC), proportional geometric mean absorption reduced scattering. depends scattering-to-absorption ratio, EAC limits assumption approach was compared standard frequency-domain procedure. A good association between two methods ( r2=0.69 ) obtained. could low-resolution maps large field view, systems, reducing increasing fNIRS sensitivity specificity brain activity without instrumentation modification.

Язык: Английский

---

Data-driven assessment of cardiovascular ageing through multisite photoplethysmography and electrocardiography

Medical Engineering & Physics, Год журнала: 2019, Номер 73, С. 39 - 50

Опубликована: Июль 26, 2019

Язык: Английский

---