A Mechanoluminescence‐Based Stress Sensing Hydrogel for Intelligent Artificial Ligament

Advanced Functional Materials, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Abstract Robust and biocompatible hydrogels are recognized as promising biomimetic soft materials to improve human life quality. To ensure their stable, reliable, safe service, the further required have non‐contact wireless stress sensing ability. Herein, a mechanoluminescence (ML) based micellar hydrogel is developed, in which surface‐modified BaSi 2 O N : Eu 2+ (M‐BSON) particles chemically incorporated into cross‐linked polyacrylamide/polymethyl acrylate (PAM/PMA) network structure. Because of interactions between M‐BSON PMA micelles, as‐fabricated composite exhibits enhanced mechanical properties with strength 2.73 MPa toughness 3.40 MJ m −3 , respectively. The chemical wrapping by hydrophobic micelles protects ML from water quenching, leading remarkable stress‐induced luminescence under environment hydrogel. its desirable performance, attractive stress‐light responsiveness, good biocompatibility, has potential be applied an intelligent artificial ligament for self‐monitoring failure warning. This work addresses inhomogeneous dispersion quenching issues structure, significantly promote applications bionic engineering.

Язык: Английский

Chemical materials involved in neural tissue engineering scaffold techniques: a narrative review

Advanced technology in neuroscience ., Год журнала: 2024, Номер 1(2), С. 244 - 260

Опубликована: Ноя. 27, 2024

Nerve injury often leads to degeneration or necrosis of damaged nerve cells, which can result in regeneration disorders during the repair process. Promoting is a critical challenge treatment nervous system diseases. With rapid advancements related research, chemical materials have shown significant promise facilitating because their excellent biocompatibility and degradability. The use tissue-engineered material scaffolds provide physical channels for regeneration. These create optimal conditions cell growth migration effectively regulate physiological processes repair. Therefore, wide range applications field This review highlights technological tools available involving materials. (1) Conductive hydrogels: Novel conductive hydrogels been developed by integrating such as graphene, carbon nanotubes, polypyrrole, promote functional recovery cells through electrical stimulation. (2) Three-dimensional printing: printing technology contributes precise control shape, porosity degradation rate scaffolds, providing customized microenvironment (3) Nanomaterials: unique physicochemical properties nanoparticles nanofibers give them great potential penetrate blood‒brain barrier, guide targeted drug delivery. (4) Local release bioactive molecules: Through design materials, controlled molecules factor, brain-derived neurotrophic factor fibroblast has realized, promotes (5) Photothermal photoacoustic stimulation: combination photothermal technologies led development capable responding photostimulation, new avenues noninvasive neurostimulation. engineering are highly effective promoting significantly improve efficiency quality In clinical practice, these techniques expected more strategies patients with injuries, improving function life. also discusses detail different biocompatibility, mechanical strength, degradability, A variety neural tissue scaffold techniques, including provision support, molecules, direct interaction cells. Although show potential, several challenges, long-term stability, individual variation response, large-scale production, still need be addressed before they translated into applications. addition, comprehensive assessment safety efficacy focus future research. Future research will on optimizing conducting trials validate techniques.

Язык: Английский

Bioengineered composite hydrogel scaffold for accelerated skin regeneration and wound repair

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 158773 - 158773

Опубликована: Дек. 1, 2024

Язык: Английский