Trivalent Chromium Ions Doped Fluorides with Both Broad Emission Bandwidth and Excellent Luminescence Thermal Stability DOI

Qiuming Lin,

Qiang Wang, Min Liao

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2021, Номер 13(15), С. 18274 - 18282

Опубликована: Апрель 8, 2021

Recently, trivalent chromium ion doped phosphors have exhibited significant application potential in broadband near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs). However, developing an NIR phosphor with both broad emission bandwidth and excellent luminescence thermal stability is still a great challenge. Here, we demonstrate phosphor, ScF3:Cr3+, which can fulfill conditions simultaneously. The prepared show the range of 700 to 1100 nm, full width at half-maximum (FWHM) 140 nm peaking 853 nm. These also (the intensity ScF3:Cr3+ keeps 85.5% 150 °C compared value room temperature). An pc-LED based on blue LED chips was fabricated tested. results that yield strong emission. This work not only provides promising for pc-LEDs but has important guiding significance effect synthesis properties Cr3+-doped fluorides.

Язык: Английский

Rare-Earth Doping in Nanostructured Inorganic Materials DOI

Bingzhu Zheng,

Jingyue Fan, Bing Chen

и другие.

Chemical Reviews, Год журнала: 2022, Номер 122(6), С. 5519 - 5603

Опубликована: Янв. 6, 2022

Impurity doping is a promising method to impart new properties various materials. Due their unique optical, magnetic, and electrical properties, rare-earth ions have been extensively explored as active dopants in inorganic crystal lattices since the 18th century. Rare-earth can alter crystallographic phase, morphology, size, leading tunable optical responses of doped nanomaterials. Moreover, control ultimate electronic catalytic performance nanomaterials scalable manner, enabling significant improvements energy harvesting conversion. A better understanding critical role prerequisite for development an extensive repertoire functional practical applications. In this review, we highlight recent advances associated applications many fields. This review covers key criteria doping, including basic structures, lattice environments, strategies, well fundamental design principles that enhance electrical, catalytic, magnetic material. We also discuss future research directions challenges controlling

Язык: Английский

Процитировано

699

Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton DOI
Michel O. Steinmetz, A.E. Prota

Trends in Cell Biology, Год журнала: 2018, Номер 28(10), С. 776 - 792

Опубликована: Июнь 2, 2018

Язык: Английский

Процитировано

400

Stimuli‐Responsive Nanocomposite Hydrogels for Biomedical Applications DOI
Pedro Lavrador,

Marco Rafael Cunha Esteves,

Vítor M. Gaspar

и другие.

Advanced Functional Materials, Год журнала: 2020, Номер 31(8)

Опубликована: Ноя. 18, 2020

Abstract The complex tissue‐specific physiology that is orchestrated from the nano‐ to macroscale, in conjugation with dynamic biophysical/biochemical stimuli underlying biological processes, has inspired design of sophisticated hydrogels and nanoparticle systems exhibiting stimuli‐responsive features. Recently, nanoparticles have been combined advanced nanocomposite hybrid platforms expanding their range biomedical applications. ease flexibility attaining modular hydrogel constructs by selecting different classes nanomaterials/hydrogels, or tuning nanoparticle‐hydrogel physicochemical interactions widely expands attainable properties levels beyond those traditional platforms. This review showcases intrinsic ability react external internal/physiological scope developing intelligent application‐oriented Moreover, are overviewed context encoding cascades recapitulate signaling interplays present native biosystems. Collectively, recent breakthroughs improve potential for operating as applications benefit tailored single multi‐responsiveness.

Язык: Английский

Процитировано

393

Engineering of Upconverted Metal–Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors DOI

Yulei Shao,

Bei Liu, Zhenghan Di

и другие.

Journal of the American Chemical Society, Год журнала: 2020, Номер 142(8), С. 3939 - 3946

Опубликована: Янв. 23, 2020

Metal-organic frameworks (MOFs) have shown great potential as nanophotosensitizers (nPSs) for photodynamic therapy (PDT). The use of such MOFs in PDT, however, is limited by the shallow depth tissue penetration short-wavelength light and oxygen-dependent mechanism that renders it inadequate hypoxic tumors. Here, to combat limitations, we rationally designed core-shell upconversion nanoparticle@porphyrinic (UCSs) combinational against UCSs were synthesized high yield through conditional surface engineering UCNPs subsequent seed-mediated growth strategy. heterostructure allows efficient energy transfer from UCNP core MOF shell, which enables near-infrared (NIR) light-triggered production cytotoxic reactive oxygen species. A hypoxia-activated prodrug tirapazamine (TPZ) was encapsulated nanopores shell heterostructures final construct TPZ/UCSs. We demonstrated TPZ/UCSs represent a promising system achieving improved cancer treatment vitro vivo via combination NIR light-induced PDT chemotherapy. Furthermore, integration nanoplatform with antiprogrammed death-ligand 1 (α-PD-L1) promotes abscopal effect completely inhibit untreated distant tumors generating specific tumor infiltration T cells. Collectively, this work highlights robust combining chemotherapy immunotherapy current limitations treatment.

Язык: Английский

Процитировано

361

Beyond the Visible: Bioinspired Infrared Adaptive Materials DOI
Jiajia Yang, Xinfang Zhang, Xuan Zhang

и другие.

Advanced Materials, Год журнала: 2021, Номер 33(14)

Опубликована: Фев. 24, 2021

Abstract Infrared (IR) adaptation phenomena are ubiquitous in nature and biological systems. Taking inspiration from natural creatures, researchers have devoted extensive efforts for developing advanced IR adaptive materials exploring their applications areas of smart camouflage, thermal energy management, biomedical science, many other IR‐related technological fields. Herein, an up‐to‐date review is provided on the recent advancements bioinspired promising applications. First overview artificial technologies presented. Recent endeavors then introduced toward camouflage radiative cooling. According to Stefan‐Boltzmann law, can be realized by either emissivity engineering or cloaks. cooling maximize radiation object through atmospheric transparency window, thus holds great potential use energy‐efficient green buildings personal management advances emerging near‐IR (NIR) also discussed, including NIR‐triggered technologies, NIR light‐fueled soft robotics, light‐driven supramolecular nanosystems. This concludes with a perspective challenges opportunities future development materials.

Язык: Английский

Процитировано

354

Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications DOI Creative Commons

Hussein M. El‐Husseiny,

Eman A. Mady, Lina Hamabe

и другие.

Materials Today Bio, Год журнала: 2021, Номер 13, С. 100186 - 100186

Опубликована: Дек. 9, 2021

Recently, biomedicine and tissue regeneration have emerged as great advances that impacted the spectrum of healthcare. This left door open for further improvement their applications to revitalize impaired tissues. Hence, restoring functions. The implementation therapeutic protocols merge biomimetic scaffolds, bioactive molecules, cells plays a pivotal role in this track. Smart/stimuli-responsive hydrogels are remarkable three-dimensional (3D) bioscaffolds intended engineering other biomedical purposes. They can simulate physicochemical, mechanical, biological characters innate Also, they provide aqueous conditions cell growth, support 3D conformation, mechanical stability cells, serve potent delivery matrices molecules. Many natural artificial polymers were broadly utilized design these intelligent platforms with novel advanced characteristics tailored functionalities fit such applications. In present review, we highlighted different types smart/stimuli-responsive emphasis on synthesis scheme. Besides, mechanisms responsiveness stimuli elaborated. Their potential was discussed. Furthermore, exploitation targeted drug delivery, smart biosensors, actuators, 4D printing, culture outlined. addition, threw light self-healing biomedicine. Eventually, presented future perceptions Conclusively, current progress enhances prospective function intelligent, sophisticated systems

Язык: Английский

Процитировано

343

NIR II-responsive photon upconversion through energy migration in an ytterbium sublattice DOI
Bo Zhou, Yan Long,

Jinshu Huang

и другие.

Nature Photonics, Год журнала: 2020, Номер 14(12), С. 760 - 766

Опубликована: Ноя. 9, 2020

Язык: Английский

Процитировано

306

Recent Progress of Rare‐Earth Doped Upconversion Nanoparticles: Synthesis, Optimization, and Applications DOI Creative Commons
Xiaohui Zhu, Jing Zhang, Jinliang Liu

и другие.

Advanced Science, Год журнала: 2019, Номер 6(22)

Опубликована: Сен. 30, 2019

Abstract Upconversion is a nonlinear optical phenomenon that involves the emission of high‐energy photons by sequential absorption two or more low‐energy excitation photons. Due to their excellent physiochemical properties such as deep penetration depth, little damage samples, and high chemical stability, upconversion nanoparticles (UCNPs) are extensively applied in bioimaging, biosensing, theranostic, photochemical reactions. Here, recent achievements synthesis, optimization, applications UCNP‐based nanomaterials reviewed. The state‐of‐the‐art approaches synthesize UCNPs past few years introduced first, followed summary several strategies optimize emissive various UCNPs. Lastly, challenges future perspectives provided conclusion.

Язык: Английский

Процитировано

297

Aggregation-Induced Emission: A Trailblazing Journey to the Field of Biomedicine DOI Creative Commons
Chunlei Zhu, Ryan T. K. Kwok, Jacky W. Y. Lam

и другие.

ACS Applied Bio Materials, Год журнала: 2018, Номер 1(6), С. 1768 - 1786

Опубликована: Окт. 30, 2018

The emergence of the aggregation-induced emission (AIE) concept significantly changes cognition scientific community toward classic photophysical phenomena. More importantly, AIE phenomenon has brought huge opportunities for analysis bioactive species, monitoring complicated biological processes, and elucidation key physiological pathological behaviors. As a class promising luminescent materials, luminogens (AIEgens) are weakly or non-emissive in form isolated molecular species but emit particularly strong fluorescence aggregated solid states. Motivated by prominent advantages such as high brightness, large Stokes shift, excellent photostability, good biocompatibility, AIEgen-based bioprobes have been widely explored field biomedicine. This review aims to provide systematic summary developmental history an in-depth perspective current landscape biomedical field, with emphasis on discussions major working principles. milestones historical development first reviewed. A total four research directions then extracted, including biomacromolecule sensing (at level), vitro cell imaging cellular vivo animal cancer theranostics levels), together clear-cut tables showing comprehensive cases further study. Lastly, this is concluded several perspectives future directions. It believed that will play vital roles exploration mysterious life processes integration various cutting-edge modalities techniques ultimate goal addressing more healthcare issues.

Язык: Английский

Процитировано

294

Large‐Pore Mesoporous‐Silica‐Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy DOI
Binbin Ding, Shuai Shao, Yu Chang

и другие.

Advanced Materials, Год журнала: 2018, Номер 30(52)

Опубликована: Ноя. 2, 2018

Reported immunoadjuvants still have many limitations, such as inferior cellular uptake capacity and biocompatibility, overly large particle sizes, single function, unsatisfactory therapeutic efficacy. Here, large-pore mesoporous-silica-coated upconversion nanoparticles (UCMSs) with a size of less than 100 nm are successfully prepared by typical silica sol-gel reaction using mesitylene pore-swelling agent applied novel immunoadjuvant. The obtained UCMSs not only show significantly higher loadings for the photosensitizers merocyanine 540 (MC540), model proteins (chicken ovalbumin (OVA)), tumor antigens (tumor cell fragment (TF)), but also employed highly efficient in vivo vaccine delivery. UCMSs-MC540-OVA under 980 near-infrared irradiation shows best synergistic immunopotentiation action, verified strongest Th1 Th2 immune responses highest frequency CD4+ , CD8+ effector-memory T cells. Additionally, nanovaccines UCMSs-MC540-TF can more effectively inhibit growth increase survival colon cancer (CT26)-tumor-bearing BALB/c mice compared either photodynamic therapy or immunological alone, suggesting enhanced immunotherapy efficacy clinical potential immunotherapy.

Язык: Английский

Процитировано

288