Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Cell, Год журнала: 2017, Номер 168(4), С. 707 - 723

Опубликована: Фев. 1, 2017

Язык: Английский

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Elements of cancer immunity and the cancer–immune set point

Nature, Год журнала: 2017, Номер 541(7637), С. 321 - 330

Опубликована: Янв. 1, 2017

Язык: Английский

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CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Nature, Год журнала: 2019, Номер 569(7755), С. 270 - 274

Опубликована: Май 1, 2019

Язык: Английский

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PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

Nature, Год журнала: 2017, Номер 545(7655), С. 495 - 499

Опубликована: Май 1, 2017

Язык: Английский

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Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy

Nature reviews. Immunology, Год журнала: 2017, Номер 17(9), С. 559 - 572

Опубликована: Май 30, 2017

Язык: Английский

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Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy

Cell, Год журнала: 2017, Номер 170(3), С. 548 - 563.e16

Опубликована: Июль 1, 2017

Язык: Английский

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Tumor-Associated Macrophages in Tumor Immunity

Frontiers in Immunology, Год журнала: 2020, Номер 11

Опубликована: Дек. 3, 2020

Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either two functionally contrasting subtypes, namely classical activated M1 alternatively M2 macrophages. The former typically exerts anti-tumor functions, including directly mediate cytotoxicity antibody-dependent cell-mediated (ADCC) to kill tumor cells; latter can promote occurrence metastasis cells, inhibit T response, angiogenesis, lead progression. Both have high degree plasticity thus be converted each other upon microenvironment changes or therapeutic interventions. As relationship between TAMs malignant tumors becoming clearer, become a promising target for developing new cancer treatment. In this review, we summarize origin TAMs, interaction with microenvironment, up-to-date treatment strategies targeting TAMs.

Язык: Английский

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Extracellular Vesicles: Unique Intercellular Delivery Vehicles

Trends in Cell Biology, Год журнала: 2016, Номер 27(3), С. 172 - 188

Опубликована: Дек. 13, 2016

Язык: Английский

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A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

Cell, Год журнала: 2018, Номер 175(2), С. 313 - 326

Опубликована: Окт. 1, 2018

Язык: Английский

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Regulatory T cells in cancer immunosuppression — implications for anticancer therapy

Nature Reviews Clinical Oncology, Год журнала: 2019, Номер 16(6), С. 356 - 371

Опубликована: Янв. 31, 2019

Язык: Английский

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