Journal of Medical Virology, Год журнала: 2025, Номер 97(4)

Опубликована: Апрель 1, 2025

ABSTRACT The gut microbiome is essential for infant health, and in recent years, the impact of enteroviruses on health disease has received increasing attention. transmission breast milk phages to gastrointestinal tract contributes shaping virome, while breastfeeding regulates colonization virome. In this study, we collected fecal samples from healthy infants analyzed distribution characteristics viral communities by metagenomic analysis, differences under different feeding practices. Our results indicate that intestinal virome consists eukaryotic viruses. Caudovirales Microviridae dominated phage composition, except Siphoviridae , which was more predominant intestines formula‐fed infants, there were no significant overall abundance other with patterns. Breastfeeding can lead a higher diversity viruses through vertical transmission, highly diverse helps maintain maturation microbiome. This study informs further research formation processes.

Язык: Английский