A zebrafish model to elucidate the impact of host genes on the microbiota

Environmental DNA, Год журнала: 2024, Номер 6(1)

Опубликована: Янв. 1, 2024

Abstract Every host species and organism provides a unique environmental niche contributing to the overall diversity of microbial ecosystems from intestine an animal oceans forests our planet. The study host–microbiota interactions has long focused on well‐established effects microbiota its host. In contrast, little focus been allocated role in these intricate interactions. However, understanding may well be essential key complexity relationship between microbiota. this study, we present model which genes can elucidated how such genetic shape host‐associated We demonstrate hologenomic approach implementing CRISPR/Cas system zebrafish combine gene with 16S metabarcoding metabolomics data. show that knocking out coding for rate‐limiting enzyme melanogenesis, tyrosinase ( tyr ), correlates changes intestinal differences abundance specific metabolites illustrating value studying impact composition function

Язык: Английский

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Host habitat rather than evolutionary history explains gut microbiome diversity in sympatric stickleback species

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Окт. 12, 2023

Host-associated microbiota can influence host phenotypic variation, fitness and potential to adapt local environmental conditions. In turn, both evolutionary history the abiotic biotic environment diversity composition of microbiota. Yet, what extent host-specific factors drive microbial remains largely unknown, limiting our understanding host-microbiome interactions in natural populations. Here, we compared intestinal between two phylogenetically related fishes, three-spined stickleback (Gasterosteus aculeatus) nine-spined (Pungitius pungitius) a common landscape. Using amplicon sequencing V3-V4 region bacterial 16S rRNA gene, characterised α β communities these fish species from brackish water freshwater habitats. Across eight locations, was higher stickleback, suggesting broader niche use this species. Habitat strong determinant species, while only explained small fraction variation gut composition. Strong habitat-specific effects overruled geographic distance historical colonisation, that microbiome correlates primarily with Interestingly, effect habitat divergence on stronger than possibly mirroring level adaptive Overall, results show reflect rather colonisation or dispersal limitation

Язык: Английский

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A review on comparative analysis of marine and freshwater fish gut microbiomes: insights into environmental impact on gut microbiota

FEMS Microbiology Ecology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 24, 2024

Abstract The gut microbiota, which includes prokaryotes, archaea, and eukaryotes like yeasts, some protozoa, fungi, significantly impact fish by affecting digestion, metabolism, the immune system. In this research, we combine various tasks carried out bacteria in of fish. This study also examines microbiome composition marine freshwater fish, identifying important bacterial species linked to different biological functions. diversity within highlights importance considering nutrition, habitat, environmental factors microbiological research on ever-changing indicates that microbial communities are specifically adapted meet needs both host its environment. can adjust a specific environment with help microbiota. is crucial for comprehending complex relationships between their aquatic environments. These discoveries have implications aquaculture practices, fisheries administration, broader ecological processes With further progress area study, knowledge acquired would offer valuable standpoint enhance our comprehension microbiology sustainability nutrition resources.

Язык: Английский

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Exchange of microbes with external environment enhances the resistibility of microbial community in fish gut during drought

Authorea (Authorea), Год журнала: 2024, Номер unknown

Опубликована: Авг. 29, 2024

Drought can profoundly alter freshwater ecosystems. Although the impacts of drought on fish have received increasing attention, our understanding response gut microbes to event remains limited. We combined approaches focusing community assembly processes and microbial core network investigate dynamic interactions between external environment during recovery periods, assessed resistibility at different periods. found that would decrease diversity affect composition function communities in gut. The exchange compensated for decline drought. In addition, effects propagated through trophic cascades. compensation mechanism reflects adaptability environments. Our study highlights environment, provides a new perspective extreme

Язык: Английский

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The impact of host genetics on microbe assemblages in three types of mrigal carp (Cirrhinus mrigala)

Aquaculture, Год журнала: 2024, Номер unknown, С. 741696 - 741696

Опубликована: Окт. 1, 2024

Язык: Английский

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