Bloodstream Infections in Critical Care Units in England, April 2017 to March 2023: Results from the First Six Years of a National Surveillance Programme
Microorganisms,
Год журнала:
2025,
Номер
13(1), С. 183 - 183
Опубликована: Янв. 16, 2025
Patients
in
critical
care
units
(CCUs)
are
at
an
increased
risk
of
bloodstream
infections
(BSIs),
which
can
be
associated
with
central
vascular
catheters
(CVCs).
This
study
describes
BSIs,
CVC-BSIs,
organism
distribution,
percentage
antimicrobial
resistant
(AMR)
organisms,
and
case
fatality
rates
(CFRs)
over
the
first
six
years
a
voluntary
national
CCU
surveillance
programme
England.
Surveillance
data
on
CVCs,
bed-days
between
04/2017
03/2023
for
adult
CCUs
were
linked
to
mortality
AMR
data,
crude
calculated.
The
CCU-BSIs
CCU-CVC-BSIs
stable
three
(3.6
1.7
per
1000
2019/20),
before
increasing
by
75%
94%
2020/21,
respectively,
returning
near
pre-pandemic
levels
2022/23.
Gram-negative
bacteria
accounted
50.3%
all
CCU-BSIs,
followed
Gram-positive
(39.6%)
Candida
spp.
(8.6%).
Klebsiella
saw
increases
AMR,
whereas
other
organisms
declines
or
similar
levels.
overall
CFR
was
30.2%.
BSI
incidence
remained
across
period,
except
increase
2020/21
reverted
These
provide
benchmark
give
insight
into
long-term
patterns
where
comparable
limited.
Язык: Английский
Contact Data and Sars-Cov-2: Retrospective Analysis of the Estimated Impact of the First UK Lockdown
Опубликована: Янв. 1, 2024
Язык: Английский
Why hospital capacity is more complex than bed capacity
BMJ,
Год журнала:
2024,
Номер
unknown, С. q883 - q883
Опубликована: Апрель 18, 2024
Язык: Английский
A truth and reconciliation in evidence based medicine
BMJ,
Год журнала:
2024,
Номер
unknown, С. q1648 - q1648
Опубликована: Июль 25, 2024
Have
you
heard
that
stem
cells
can
develop
into
any
type
of
cell
in
the
body?It's
a
claim
that's
been
"very
rigorously
disproven,"
says
Charles
Murry
from
University
Washington
Seattle
(doi:10
Язык: Английский
The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England
Journal of Epidemiology and Global Health,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 8, 2024
Abstract
Background
As
the
impact
of
SARS-CoV-2
pandemic
extends
into
2023
and
beyond,
treatment
outcomes
infected
patients
continues
to
evolve.
Unlike
earlier
in
there
are
now
further
infectious
disease
pressures
placed
on
hospitals,
which
influence
patient
care
triage
decisions.
Methods
The
manuscript
uses
individual
records
linked
with
associated
hospital
management
information
system
pressure
characteristics
attribute
COVID-19
hospitalisation
fatality
risks
(HFR)
using
generalised
additive
mixed
effects
models.
Results
Between
01
September
2022
09
October
2023,
risk
England
was
estimated
as
12.71%
(95%
confidence
interval
(CI)
12.53%,
12.88%).
Staff
absences
had
an
adjusted
odds
ratio
1.038
CI
1.017,
1.060)
HFR
when
accounting
for
characteristics.
Interpretation
This
observational
research
presents
evidence
that
a
range
local
can
have
meaningful
death
from
once
hospitalised
should
be
accounted
reporting
estimates.
We
show
both
case
mix
estimates
outcomes.
Язык: Английский
A modular approach to forecasting COVID-19 hospital bed occupancy
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 15, 2024
Abstract
Monitoring
the
number
of
COVID-19
patients
in
hospital
beds
was
a
critical
component
Australia’s
real-time
surveillance
strategy
for
disease.
From
2021–2023,
we
produced
short-term
forecasts
bed
occupancy
to
support
public
health
decision
making.
In
this
work,
present
model
forecasting
ward
and
intensive
care
unit
(ICU)
occupied
by
cases.
The
simulates
stochastic
progression
through
system
is
fit
reported
counts
using
an
approximate
Bayesian
method.
We
do
not
directly
infection
dynamics
—
instead
taking
independently
case
incidence
as
input
enabling
independent
development
our
from
that
underlying
forecast(s).
evaluate
performance
21-day
ICU
across
eight
states
territories
between
March
September
2022,
when
major
waves
Omicron
variant
SARS-CoV-2
were
occurring
throughout
country.
Forecasts
on
average
biased
downwards
immediately
prior
epidemic
peaks
upwards
post-peak.
Forecast
best
jurisdictions
with
largest
population
sizes.
Our
burden
weekly
national
decision-making
committees
response.
Язык: Английский