New Antidepressant Prescriptions Before, During, and After the COVID-19 Pandemic: Sex and Age Differences in a Population-Based Ecological Study

Healthcare, Год журнала: 2025, Номер 13(5), С. 502 - 502

Опубликована: Фев. 26, 2025

Purpose: It is well established that the COVID-19 pandemic has increased incidence of depressive symptoms in general population. So far, there are no studies analyzing how this affected prescription antidepressants. Methods: We retrospectively estimated new cases depression by prescriptions antidepressive agents over a period 6 years distributed three periods 2 each: pre-pandemic, pandemic, and post-pandemic, running from March 2018 to February 2024. This research was conducted healthcare area with 130,000 individuals Spain. Results: New for antidepressants significantly during even more post-pandemic period, increase being greater women than men. During specifically due an among people under 20 age, while occurred all age groups. In subgroup analysis, we found exclusively number aged 40 or who were prescribed antidepressant, been significant both male female patients antidepressant groups compared two previous periods, except young men up years. Conclusions: Our study highlights importance addressing mental health population parallel physical problems adapting systems accordingly.

Язык: Английский

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Trend analysis of antidepressant consumption in Italy from 2008 to 2022 in a public health perspective

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 9, 2025

Depression is an important public health issue. Over the years, consumption of antidepressants has increased in population, which on one hand may mean diagnostic accuracy, but other could a problem inappropriate and prescribing. The aim study to analyze trends antidepressant major drug classes Italy last 15 years provide useful insights for policymakers. Data were collected from Osservasalute OsMed reports 2008 2022. We included overall three subclasses most widely used drugs: selective serotonin reuptake inhibitors (SSRIs), norepinephrine (SNRIs), tricyclic (TCAs). expressed as daily defined dose (DDD) per 1,000 inhabitants. A joinpoint analysis was conducted each data point order describe trend identify Annual Percentage Change (APC) Average Percent (AAPC). In Italy, there increase 36.7% over period. Overall, Joinpoint shows significant AAPC + 2.31%. Analyzing also showed SSRIs (AAPC = 1.46%) SNRIs 2.14%). contrast, decrease TCAs - 1.46%). use been increasing steadily considered Public Health plays key role proposing solutions improve mental population. Targeted interventions must be carried out raise awareness among policy makers, clinicians

Язык: Английский

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Patterns of Antidepressant and Anxiolytic Use and Spending in 14 European Countries (2012-2021): A Comprehensive Time Series Analysis

Health Services Insights, Год журнала: 2024, Номер 17

Опубликована: Янв. 1, 2024

The assessment of antidepressant and anxiolytic consumption expenditures represents a reliable barometer the burden such mental health disorders effectiveness relative healthcare services.

Язык: Английский

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Insight into Potential Long COVID Effects: Antidepressant Use in Post SARS-CoV-2 Infection Scenarios. A Multiregional Nested Case-Control Study

Опубликована: Янв. 1, 2024

Background: This study aimed to investigate the impact of previous SARS-CoV-2 infection and role vaccination in onset neuropsychiatric conditions, evaluated through antidepressant prescriptions.Methods: A case-control from three Italian Regions, risk new prescriptions relation exposure vaccination. The population consisted adults who did not receive year preceding period considered. Individuals with newly prescribed antidepressants (cases) were matched 1:1 by sex age non-users (controls) during same period. Pooled estimates regional Odds Ratios (ORs) obtained inverse variance-weighted random-effects analyses.Findings: base 6,658,840 individuals. Those previously infected had a higher receiving prescription this association was stronger among those hospitalized due (non-hospitalized: OR 1·30, 95% CI 1·21-1·40; hospitalized: 2·93, 2·73-3·15). acted as an effect modifier, reducing excess risk. Among individuals severe infection, pooled for 3·68 (95% = 2·99-4·54) unvaccinated 2·42 2·10-2·78) vaccinated.Interpretation: results confirm factor symptoms. Antidepressant treatment initiation much more likely after COVID-19 but reduced such risk.Funding: funded Ministry Health.Declaration Interest: All authors declare that they have no conflict interest.Ethical Approval: research protocol approved National Ethics Committee (AOO-ISS – 19/04/2022 0015066 Class: PRE BIO CE 01.00).

Язык: Английский

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Estimated cardiorespiratory fitness level and utilization of antidepressants among older adults before and after the COVID-19 lockdown: Findings from the HUNT4 Trondheim 70+ study

Mental health and physical activity, Год журнала: 2024, Номер 27, С. 100631 - 100631

Опубликована: Сен. 12, 2024

Язык: Английский

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Tracking the surge of psychiatric pharmaceuticals in urban rivers of Curitiba amidst and beyond the SARS-CoV-2 pandemic

The Science of The Total Environment, Год журнала: 2024, Номер 954, С. 176685 - 176685

Опубликована: Окт. 9, 2024

Язык: Английский

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Insight into potential Long COVID effects: antidepressant use in post SARS-CoV-2 Infection scenarios. A Multiregional Nested Case-Control Study

Psychiatry Research, Год журнала: 2024, Номер 344, С. 116290 - 116290

Опубликована: Ноя. 28, 2024

Язык: Английский

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