The relationship between the phenotype of long COVID symptoms and one-year psychosocial outcomes: an exploratory clustering analysis
Psychology Health & Medicine,
Год журнала:
2025,
Номер
unknown, С. 1 - 17
Опубликована: Фев. 17, 2025
The
impact
of
Coronavirus
Disease
2019
(COVID-19)
is
not
limited
to
acute
symptoms;
it
also
extends
post-infection
sequelae,
such
as
long
COVID
and
post-COVID
conditions.
These
conditions
are
characterized
by
various
symptoms,
malaise,
fatigue,
cognitive
dysfunction,
considered
reflect
different
underlying
pathologies.
Using
a
cluster
analysis,
we
hypothesized
that
may
have
psychosocial
outcomes
depending
on
the
phenotype.
This
study
based
COVID-19
RECOVERY
STUDY
II
(CORES
II)
conducted
in
20
centers
Japan.
CORES
included
patients
aged
years
older
who
were
hospitalized
discharged
alive
between
April
September
2021.
In
II,
information
collected
at
hospitalization
was
followed
an
investigation
one
year
after
diagnosis
into
physical
mental
health,
patients'
social
circumstances.
Long
symptoms
month
infection,
well-being,
including
anxiety,
depression,
post-traumatic
stress
disorder,
quality
life
(QOL),
onset
assessed
via
questionnaires
provided
diagnosis.
We
performed
analysis
symptoms.
compared
status
clusters.
identified
five
clusters
746
patients.
severe
multi-organ
olfactory
gustatory
disturbances,
shortness
breath,
muscle
weakness,
hair
loss.
dysfunction
large
number
with
malaise
more
likely
poor
onset.
addition,
disturbance
appeared
second
highest
depression
anxiety
scores
cluster.
results
obtained
five-symptom
suggest
phenotype
disturbances
has
consequences.
Patients
these
phenotypes
require
extensive
follow-ups
interventions.
Язык: Английский
All-cause healthcare resource utilization and costs among community-managed adults with long-COVID in France, 2020–2023
Journal of Medical Economics,
Год журнала:
2025,
Номер
28(1), С. 535 - 543
Опубликована: Апрель 8, 2025
The
clinical
and
economic
burden
of
long
COVID
is
poorly
understood.
We
aim
to
assess
all-cause
healthcare
resource
utilization
(HCRU)
costs
in
the
primary
care
setting
among
adults
with
France.
A
retrospective
cohort
study
using
electronic
records
(EHRs)
confirmed
and/or
probable
COVID-19
patients
from
Health
Improvement
Network
(THIN)
data
between
March
2020
December
2022
was
conducted.
Long
identified
per
World
Organization
(WHO)
definition
as
suggestive
symptoms
present
≥3
months
following
acute
SARS-CoV-2
infection.
Patients'
characteristics,
HCRU,
direct
indirect
(National
Insurance-based
prices)
were
summarized.
Costs
previous
infection
who
developed
COVID,
did
not
develop
(COVID
only),
contemporaneous
controls
without
compared
(Non-COVID).
30,122
(11.6%)
adults;
mean
(SD)
age
50
(17)
years,
63.6%
female
27.5%
had
a
Charlson
Comorbidity
Index
score
>2.
During
post-infection
follow-up
(mean
=
13
months),
97.3%
general
practitioner
consultations
(GP)
62.4%
nursing
care.
highest
during
first
post-diagnosis
year
patient
€2,443
(total
cost
€52
million),
including
for
GP
(€208)
specialist
(€170)
consultations,
outpatient
procedures
(€413),
retail
pharmacy
use
(€595),
biological
testing
(€147),
medical
device
usage
(€172).
Patients
additional
€163
€176
when
only
Non-COVID
cohorts,
respectively.
Since
THIN
database
generated
EHRs,
there
possibility
measurement/documentation
errors
missing
values
which
could
compromise
validity
accuracy
certain
results.
associated
non-negligible
French
system.
These
findings
reinforce
importance
optimizing
long-term
allocation
infected
SARS-CoV-2.
Язык: Английский
Health and social service provider perspectives on challenges, approaches, and recommendations for treating long COVID: a qualitative study of Canadian provider experiences
BMC Health Services Research,
Год журнала:
2025,
Номер
25(1)
Опубликована: Апрель 8, 2025
Many
people
who
contract
the
SAR-CoV-2
virus
present
with
multiple
persistent
and
debilitating
physical,
cognitive
mental
health
symptoms
that
endure
beyond
acute
infection
period.
This
new
syndrome
-
generally
referred
to
as
long
COVID
negatively
affects
patients'
emotional
wellbeing
quality
of
life,
presents
a
major
challenge
for
treatment
providers.
Considering
lack
evidence-based
supports,
this
qualitative
descriptive
study
explores
experiences
Canadian
social
service
providers
working
individuals
COVID,
well
their
suggestions
intervention
development.
Twenty
between
ages
29
57
across
Canada
completed
virtual
individual
interviews
discuss
care
recommendations
COVID.
Participants
were
from
range
sectors,
including
primary
care,
rehabilitation,
health,
community
support.
Interviews
recorded,
transcribed,
analyzed
using
codebook
thematic
analysis.
Four
themes
illustrated
providers'
(1)
selecting
personalized
treatments
based
on
patient
presentation
similar
conditions
amidst
uncertainty;
services,
(2)
building
an
integrated
model
care;
(3)
providing
holistic
support
patients
families
through
psychoeducation
daily
living
resources;
(4)
caring
in
are
adopting
approaches
address
symptom
persistence
face
considerable
knowledge
gap.
A
comprehensive,
pathway
is
needed
physical
psychosocial
while
increasing
provider
preparedness
treat
complex
condition.
Язык: Английский