BMJ Open,
Год журнала:
2016,
Номер
6(3), С. e009781 - e009781
Опубликована: Март 1, 2016
Polypharmacy
and
multimorbidity
are
common
in
long-term
care
facilities
(LTCFs).
Reducing
polypharmacy
may
reduce
adverse
events
maintain
quality
of
life.
Deprescribing
refers
to
reducing
medications
after
consideration
therapeutic
goals,
benefits
risks,
medical
ethics.
The
objective
was
use
nominal
group
technique
(NGT)
generate
then
rank
factors
that
general
practitioners
(GPs),
nurses,
pharmacists
residents
or
their
representatives
perceive
most
important
when
deciding
whether
not
deprescribe
medications.Qualitative
research
using
NGT.Participants
were
invited
if
they
worked
with,
resided
LTCFs
across
metropolitan
regional
South
Australia.11
residents/representatives,
19
GPs,
12
nurses
14
participated
six
separate
groups.Individual
groups
residents/representatives
convened.
Using
NGT
each
ranked
perceived
be
deprescribe.
Then,
NGT,
the
prioritised
from
individual
discussed
by
a
multidisciplinary
comprised
resident
representatives,
pharmacists.No
two
had
same
priorities.
GPs
'evidence
for
deprescribing'
'communication
with
family/resident'
as
factors.
Nurses
'GP
receptivity
'nurses
ability
advocate
residents'
important.
Pharmacists
'clinical
appropriateness
therapy'
'identifying
goals
care'
Residents
'wellbeing
resident'
'continuity
nursing
staff'
'adequacy
medication
history'
important.While
different
factors,
contrasting
emerged.
Future
deprescribing
interventions
need
consider
similarities
differences
within
range
health
professionals.
British Journal of General Practice,
Год журнала:
2016,
Номер
66(649), С. e552 - e560
Опубликована: Июнь 6, 2016
Background
Deprescribing
describes
the
complex
process
that
is
required
for
safe
and
effective
cessation
of
medications
are
likely
to
cause
more
harm
than
benefit.
Knowledgeof
older
adults'
carers'
attitudes
towards
deprescribing
will
enhance
shared
decision
making
in
medication
optimisation.
Aim
To
explore
views,
beliefs,
adults
carers
on
deprescribing.
Design
setting
Qualitative
focus
group
study
New
South
Wales,
Australia.
Method
Four
groups
with
14
were
conducted.
Results
analysed
using
a
previously
developed
framework
(directed
content
analysis)
additional
conventional
analysis.
Results
The
willingness
both
have
one
or
deprescribed
was
influenced
by
following
main
themes:
their
perception
appropriateness
medication;
fear
outcomes
withdrawal;
dislike
taking
medications;
availability
withdrawal
(including
discussion
healthcare
professional
knowing
could
be
restarted
if
necessary).
A
patient's
regular
GP
identified
as
strong
influence
against
withdrawal.
themes
supported
framework.
An
theme
unique
complexity
involved
decisions
about
care
recipients.
Conclusion
This
highlights
discussions
between
olderadult
carer
withdrawing
should
address
reasons
GPs
aware
major
patients
regularly
discuss
current
use
carers.
Implementation Science,
Год журнала:
2016,
Номер
11(1)
Опубликована: Дек. 1, 2016
Collaborative
care
is
an
increasingly
popular
approach
for
improving
quality
of
people
with
mental
health
problems
through
intensified
and
structured
collaboration
between
primary
providers
professionals
specialized
psychiatric
expertise.
Trials
have
shown
significant
positive
effects
patients
suffering
from
depression,
but
since
collaborative
a
complex
intervention,
it
important
to
understand
the
factors
which
affect
its
implementation.
We
present
qualitative
systematic
review
enablers
barriers
implementing
anxiety
depression.
developed
comprehensive
search
strategy
in
cooperation
research
librarian
performed
five
databases
(EMBASE,
PubMed,
PsycINFO,
ProQuest,
CINAHL).
All
authors
independently
screened
titles
abstracts
reviewed
full-text
articles.
Studies
were
included
if
they
published
English
based
on
original
data
implementation
intervention
targeted
at
depression
or
adult
patient
population
high-income
country.
Our
subsequent
analysis
employed
normalization
process
theory
(NPT).
17
studies
our
11
conducted
USA,
UK,
one
Canada.
identified
several
within
four
major
analytical
dimensions
NPT.
Securing
buy-in
among
was
found
be
critical
sometimes
difficult.
Enablers
physician
champions,
reimbursement
extra
work,
feedback
effectiveness
care.
The
social
professional
skills
managers
seemed
integrating
clinic.
Day-to-day
also
facilitated
by
being
located
clinic
this
supports
regular
face-to-face
interactions
physicians
managers.
following
areas
require
special
attention
when
planning
interventions:
effective
educational
programs,
especially
managers;
issues
relation
providers;
good
systems
communication
monitoring;
promoting
interaction
physicians,
preferably
co-location.
There
need
well-sampled,
in-depth
settings
outside
USA
UK.
PLoS ONE,
Год журнала:
2016,
Номер
11(8), С. e0161248 - e0161248
Опубликована: Авг. 12, 2016
Class
specific
deprescribing
guidelines
could
help
clinicians
taper
and
stop
medications
no
longer
needed
or
which
may
be
causing
more
harm
than
benefit.
We
set
out
to
develop
methodology
create
such
using
evidence-based
methods
for
guideline
development,
evidence
synthesis
recommendation
rating.Using
a
comprehensive
checklist
successful
enterprise,
we
conducted
national
modified
Delphi
consensus
process
identify
priorities
guidelines,
then
scoping
exercises
feasible
topics,
sequentially
developed
three
guidelines.
selected
development
team
members
clinical
expertise;
GRADE
member
worked
with
staff
ensure
processes
were
followed.
used
systematic
searches
reviews
of
trials
drug
classes,
class
effectiveness,
narrative
syntheses
contextual
questions
inform
recommendations
development.
Our
8
step
included
defining
scope
purpose,
developing
logic
model
guide
the
generate
key
questions,
setting
criteria
admissible
conducting
reviews,
synthesizing
considering
additional
information
performing
quality
estimates,
formulating
providing
strength
estimations,
adding
considerations,
stakeholder
review
finally
updating
content
pre-publication.
Innovative
aspects
outcomes
tapering
stopping
medication,
incorporating
medication
into
rating.
Through
(for
proton
pump
inhibitors,
benzodiazepine
receptor
agonists
antipsychotics)
associated
decision-support
algorithms,
able
gradually
hone
methodology;
each
will
published
separately.Our
demonstrates
importance
searching
short
long-term
outcomes,
showing
benefits
studying
patient
preferences.
This
publication
support
future
Therapeutic Advances in Drug Safety,
Год журнала:
2015,
Номер
6(6), С. 212 - 233
Опубликована: Ноя. 3, 2015
The
positive
benefit–risk
ratio
of
most
drugs
is
decreasing
in
correlation
to
very
old
age,
the
extent
comorbidity,
dementia,
frailty
and
limited
life
expectancy
(VOCODFLEX).
First,
we
review
inappropriate
medication
use
polypharmacy
(IMUP)
globally
highlight
its
negative
medical,
nursing,
social
economic
consequences.
Second,
expose
main
clinical/practical
perceptual
obstacles
that
combine
create
vicious
circle
eventually
makes
us
feel
frustrated
hopeless
treating
VOCODFLEX
general,
our
‘war
against
IMUP’
particular.
Third,
summarize
international
approaches/methods
suggested
tried
different
countries
an
attempt
improve
ominous
clinical
outcomes
IMUP;
these
include
a
variety
clinical,
pharmacological,
computer-assisted
educational
programs.
Lastly,
suggest
new
comprehensive
perception
for
providing
good
medical
practice
21st
century.
This
includes
principles
research,
education
guidelines
completely
from
‘single
disease
model’
research
rules
were
raised
upon
somehow
‘fanatically’
adopted
20th
perception,
based
on
palliative,
geriatric
ethical
principle,
may
provide
fresh
tools
general
reducing
IMUP
BMJ Open,
Год журнала:
2016,
Номер
6(3), С. e009781 - e009781
Опубликована: Март 1, 2016
Polypharmacy
and
multimorbidity
are
common
in
long-term
care
facilities
(LTCFs).
Reducing
polypharmacy
may
reduce
adverse
events
maintain
quality
of
life.
Deprescribing
refers
to
reducing
medications
after
consideration
therapeutic
goals,
benefits
risks,
medical
ethics.
The
objective
was
use
nominal
group
technique
(NGT)
generate
then
rank
factors
that
general
practitioners
(GPs),
nurses,
pharmacists
residents
or
their
representatives
perceive
most
important
when
deciding
whether
not
deprescribe
medications.Qualitative
research
using
NGT.Participants
were
invited
if
they
worked
with,
resided
LTCFs
across
metropolitan
regional
South
Australia.11
residents/representatives,
19
GPs,
12
nurses
14
participated
six
separate
groups.Individual
groups
residents/representatives
convened.
Using
NGT
each
ranked
perceived
be
deprescribe.
Then,
NGT,
the
prioritised
from
individual
discussed
by
a
multidisciplinary
comprised
resident
representatives,
pharmacists.No
two
had
same
priorities.
GPs
'evidence
for
deprescribing'
'communication
with
family/resident'
as
factors.
Nurses
'GP
receptivity
'nurses
ability
advocate
residents'
important.
Pharmacists
'clinical
appropriateness
therapy'
'identifying
goals
care'
Residents
'wellbeing
resident'
'continuity
nursing
staff'
'adequacy
medication
history'
important.While
different
factors,
contrasting
emerged.
Future
deprescribing
interventions
need
consider
similarities
differences
within
range
health
professionals.