Environmental Science Advances, Год журнала: 2024, Номер 4(1), С. 57 - 76
Опубликована: Ноя. 4, 2024
A form of chronic kidney disease has been described in people without any known risk factors. These cases are referred to as an unknown etiology (CKDu).
Язык: Английский
Nature Reviews Disease Primers, Год журнала: 2025, Номер 11(1)
Опубликована: Янв. 30, 2025
Язык: Английский
Процитировано
7
Nephrology, Год журнала: 2025, Номер 30(1)
Опубликована: Янв. 1, 2025
ABSTRACT Chronic kidney disease (CKD) prevalence varies widely across different regions of India. We aimed to identify the status CKD in India, by systematically reviewing published community‐based studies between period January 2011 December 2023. PubMed, Scopus, and EMBASE were searched for peer‐reviewed evidence. Records identified full‐text screening imported into Litmaps literature review tool more relevant studies. Two researchers independently examined retrieved data. Quality assessment was conducted using JBI A random effects model pooled estimates. Subgroup analysis, meta‐regression sensitivity analysis explored heterogeneity sources estimated robustness. Publication bias assessed with a DOI plot LFK index. Among 7062 records identified, 18 included this review. The from India 13.24% (confidence intervals (CI) 10.52 16.22, I 2 99%, p < 0.001). among men 14.80%, while women it 13.51%. Southern administrative zone had 14.78%. Pooled higher rural areas (15.34%) compared those urban (10.65%). Significant found. analyses based on sampling strategy, quality score, publication year, eGFR estimation equation showed no effect prevalence. Prediction Intervals confirmed future will fall 2.64% 30.17%. This indicates rising trend (from 11.12% during 2017, 16.38% 2018 2023) Indians aged 15 years above, over past years. More regional research is needed tailor‐make interventions detect early manage well.
Язык: Английский
Процитировано
2
International Journal of Environmental Research and Public Health, Год журнала: 2024, Номер 21(4), С. 468 - 468
Опубликована: Апрель 11, 2024
Background: Exposure to environmental pollutants such as metals and Per- Polyfluoroalkyl Substances (PFAS) has become common increasingly associated with a decrease in the estimated Glomerular Filtration Rate (eGFR), which is marker often used measure chronic kidney disease (CKD). However, there are limited studies involving use of both eGFR urine albumin creatinine ratio (uACR), more comprehensive markers determine presence CKD complexity pollutant exposures response interactions, especially for combined PFAS, not been comprehensively elucidated. Objective: This study aims assess individual effects perfluorooctanoic acid (PFOA), perfluorooctanesulfonic (PFOS), Cadmium (Cd), Mercury (Hg), Lead (Pb) exposure on using data from National Health Nutritional Examination Survey (NHANES) 2017–2018. Methods: We employed bivariate logistic regression Bayesian Kernel Machine Regression (BKMR) our analysis data. Results: Logistic results revealed positive association between PFOA CKD. Our BKMR non-linear bi-phasic relationship metal In univariate exposure–response function plot, Cd Hg exhibited U N-shaped interaction, indicated non-additive low high addition, two mixture that had U-shaped at different quantiles Pb, Hg, PFOA, PFOS, indicating levels CKD, implying complex biological interaction. Hg’s interaction plot demonstrated across all Cd, 75th quantile Pb 50th PFOS. Furthermore, PIP underscored Cd’s consistent (PIP = 1.000) followed by 0.9984), then PFOS closely related 0.7880 0.7604, respectively, finally 0.6940), contributing least among five though significant. Conclusions: findings pollutants, particularly These highlight need public health interventions strategies mitigate cumulative effect PFAS elucidate significance utilizing advanced statistical methods tools understand impact human health. Further research needed mechanistic pathways metal-induced injury longitudinal required ascertain long-term these exposures.
Язык: Английский
Процитировано
9
Diabetes Obesity and Metabolism, Год журнала: 2025, Номер unknown
Опубликована: Фев. 14, 2025
Abstract Background and Aims Adequate lipid control has emerged as a key factor in the prevention management of chronic kidney disease (CKD). Remnant cholesterol (RC), lipoprotein with an established association cardiovascular risk, been investigated context CKD. Given conflicting results from recent studies, we performed this meta‐analysis to summarize existing evidence on between RC Methods Medline, Cochrane Library Scopus were searched until 16 September 2024. Double‐independent study selection, data extraction quality assessment performed. Evidence was pooled using random‐effects meta‐analyses. We set primary end‐point interest Results Twelve studies (4 139 674 participants) included. Participants values highest quantile had significantly greater odds CKD compared those lowest (Odds Ratio [OR] = 1.46, 95% confidence interval [CI] 1.26–1.68). In sensitivity analysis confined subjects type 2 diabetes (T2D), higher also exhibited increased (OR CI 1.20–1.78). A significant inverse observed estimated glomerular filtration rate (Mean Difference [MD] −1.43 mL/min/1.73 m for each 1 mmol/L increase RC, [−2.67, −0.19]). Additionally, individuals T2D‐related 24% risk progression end‐stage renal standard deviation (Hazard [HR] 1.24, 1.04–1.47). Conclusions is directly associated Beyond traditional markers, emphasis should be placed levels or at
Язык: Английский
Процитировано
1
Nephrology Dialysis Transplantation, Год журнала: 2024, Номер 39(9), С. 1384 - 1391
Опубликована: Март 8, 2024
We are currently facing a pandemic of physical inactivity that might contribute to the growing prevalence chronic kidney disease (CKD). Here, we summarize available evidence on association between activity and CKD, also review effects exercise intervention in affected patients. Physical activity/exercise act as polypill against preventing its development or even exerting beneficial once it is established (i.e. improvements patients' fitness cardiovascular risk, well function). Exercise benefits found at advanced CKD stages patients under hemodialysis. The biological mechanisms behind clinical discussed. An active lifestyle appears cornerstone prevention management.
Язык: Английский
Процитировано
7
The Science of The Total Environment, Год журнала: 2024, Номер 921, С. 170975 - 170975
Опубликована: Фев. 13, 2024
Язык: Английский
Процитировано
6
BMJ Open, Год журнала: 2023, Номер 13(10), С. e075437 - e075437
Опубликована: Окт. 1, 2023
Objective To analyse the trends of diseases burden attributed to high body mass index (BMI), including overweight and obesity, in Asia from 1990 2019. Design Observational study. Setting The data 45 countries regions were obtained Global Burden Disease Study 2019 database. Main outcome measures Numbers, age-standardised rate (ASR) deaths disability-adjusted life years (DALYs), corresponding estimated annual percentage changes (EAPCs), attributable BMI 2019, analysed by regions, genders age. We also causes DALYs that are over this period. Results In all 2 329 503, with increases 265% compared 1990. Over three decades, related have increased 268%. ASRs both showed continuous upward during period (EAPC 1.39; 95% certainty interval [95% CI] 1.35 1.43 for deaths; EAPC 1.8; CI 1.76 1.84 DALYs), while declined high-income areas −2.03 −1.26). By geographical disease Central West been fluctuating at levels, but Pacific decreasing ASR −2.03) period, was changing women men, tends ageing. addition, diabetes most affected BMI, cancer middle-aged elderly people. Conclusions has experienced great changes. It is necessary promote prevention obesity chronic a comprehensive manner, especially low-income areas, men elderly.
Язык: Английский
Процитировано
13
Journal of Clinical Nursing, Год журнала: 2024, Номер 33(10), С. 3815 - 3830
Опубликована: Май 8, 2024
To identify and synthesise qualitative studies on barriers facilitators perceived by dialysis patients in relation to self-care disease management.
Язык: Английский
Процитировано
5
Renal Failure, Год журнала: 2024, Номер 46(2)
Опубликована: Сен. 19, 2024
Chronic Kidney Disease (CKD) has emerged as a significant global health issue. This study aimed to reveal and predict the epidemiological characteristics of CKD.
Язык: Английский
Процитировано
5
Kidney International Supplements, Год журнала: 2024, Номер 13(1), С. 12 - 28
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
4