Clinical Oncology, Год журнала: 2024, Номер 39, С. 103744 - 103744
Опубликована: Дек. 29, 2024
Язык: Английский
Опубликована: Авг. 20, 2024
Background: Lower limb length discrepancy (LLD) in children and adolescents, often due to congenital or acquired conditions, is treated achieve equality alignment, optimizing function minimizing cosmetic concerns for an active adulthood. This study evaluated the Health-Related Quality of Life (HRQoL) physical functioning adults who underwent unilateral lengthening with circular external fixators (EFs) childhood. Methods: Fifty patients at a median age 14.9 years completed Short Form 36 (SF-36) Stanmore Limb Reconstruction Score (SLRS) questionnaires adulthood, follow-up 8.9 years. Results: Among 50 patients, 38 single (21 tibia, 12 femur, 5 both), while required multiple cycles. The residual LLD was 0.4 cm, (24%) having over 2 cm. Complications occurred 67% procedures, mainly prolonged healing. Physical mental health scores were significantly lower than normative data. mean Component Summary 52.2 ± 7.2 (p = 0.20). Mental 43.9 8.6 0.001), notably cases. Many SLRS items (Pain, Social, Function, Work, Emotions) strongly correlated SF-36 items. Conclusions: highlights challenges treating LLD, emphasizing significant impact, especially cases, necessity comprehensive long-term care strategies. These findings suggest that future therapeutic strategies should focus on both psychological outcomes improve overall recovery treatment.
Язык: Английский
Процитировано
1
Procedia Computer Science, Год журнала: 2024, Номер 241, С. 600 - 605
Опубликована: Янв. 1, 2024
This concise analysis examines the application of AI, particularly chatbots and natural language processing (NLP), to enhance maternal-infant healthcare in Spain Brazil, where maternal mortality rates are significantly different, as well birth rate reproductive health planning or control. The will be preliminary tested complex situations regarding these two use cases. It highlights integration disruptive technologies into prenatal care, emphasizing role AI facilitating personalized self-management through data acquisition on parameters, such weight gain, blood pressure, incontinence, mental health, nutrition physical activity. study reflects impact digital tools optimizing patient engagement early diagnosis alarm symptoms, showcasing potential m-Health applications transforming care practices contributing attaining Global Health Objectives for 2030.
Язык: Английский
Процитировано
1
Journal of Patient-Reported Outcomes, Год журнала: 2024, Номер 8(1)
Опубликована: Сен. 30, 2024
Язык: Английский
Процитировано
1
Journal of Patient-Reported Outcomes, Год журнала: 2024, Номер 8(1)
Опубликована: Ноя. 8, 2024
Abstract Background Health systems need tools to assess patient’s experience of service, but existing lack reliability and validity assessment. Our aim is investigate the factor structure, reliability, validity, item parameters interpretability parent version Experience Service Questionnaire (ESQ) for practical use in Greece. Methods A total 265 caregivers that were using mental health services Greece participated this study as part Nationwide cross-sectional survey from Child Adolescent Mental Initiative (CAMHI). Confirmatory Factor Analysis was used test structure. Reliability all models measured with omega coefficients. Tobit regression analysis convergent discriminant specifically designed questions. Item assessed via Response Theory. Interpretability by means IRT-based scores. Results We found ESQ best represented scored a unidimensional construct, given potential subscales would not have enough apart general factor. Convergent demonstrated, who perceived their child benefited received care had 6.50 higher summed scores (SMD = 1.14, p < 0.001); while those believed needed additional help 5.08 lower on −0.89, 0.001). Average z-scores provided five meaningful categories services, terms user satisfaction, compared national average. Conclusions presents evidence provides recommendations its can be measure service might drive improvements delivery Greek sector.
Язык: Английский
Процитировано
1
Exploration of Immunology, Год журнала: 2024, Номер unknown, С. 802 - 821
Опубликована: Дек. 4, 2024
Cancer-related pain represents one of the most common complaints cancer patients especially for those with advanced-stage disease and/or bone metastases. More effective therapeutic strategies are needed not only to improve survival but also relieve cancer-related pain. In last decade, immune checkpoint inhibitor (ICI)-based immunotherapy targeting programmed cell death-1 (PD-1) and its ligand 1 (PD-L1) has revolutionized care. Beyond anticancer role, PD-1/PD-L1 axis pathway is involved in many other physiological processes. PD-L1 expression found both malignant tissues normal including dorsal root ganglion, spinal cord. Through interaction PD-1, can modulate neuron excitability, leading suppression inflammatory, neuropathic, Therefore, since intricate relationship between should be largely dissected, this comprehensive review explores complex PD-1/PD-L1-based It delves into potential mechanisms through which might pathways, neuroinflammation, neuromodulation, opioid mechanisms, Understanding these crucial developing future research directions order optimize management patients. Finally, article discusses role artificial intelligence (AI) advancing clinical practice context. AI-based strategies, such as analyzing large datasets creating predictive models, identify patterns correlations These tools assist healthcare providers tailoring treatment plans individual patients, ultimately improving outcomes quality life undergoing immunotherapy.
Язык: Английский
Процитировано
1
medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown
Опубликована: Июль 5, 2024
Abstract Background Health systems need tools to assess patient’s experience of service, but existing lack reliability and validity assessment. Our aim is investigate the factor structure, reliability, validity, item parameters interpretability parent version Experience Service Questionnaire (ESQ) for practical use in Greece. Methods A total 265 caregivers that were using mental health services Greece participated this study as part Nationwide cross-sectional survey from Child Adolescent Mental Initiative (CAMHI). Confirmatory Factor Analysis was used test structure. Reliability all models measured with omega coefficients. Tobit regression analysis convergent discriminant specifically designed questions. Item assessed via Response Theory. Interpretability by means IRT-based scores. Results We found ESQ best represented scored a unidimensional construct, given potential subscales would not have enough apart general factor. Convergent demonstrated, who perceived their child benefited received care had 6.50 higher summed scores (SMD=1.14, p<0.001); while those believed needed additional help 5.08 lower on (SMD=-0.89, p<0.001). Average z-scores provided five meaningful categories services, terms user satisfaction, compared national average. Conclusions presents evidence provides recommendations its can be measure service might drive improvements delivery Greek sector.
Язык: Английский
Процитировано
0
Children, Год журнала: 2024, Номер 11(11), С. 1322 - 1322
Опубликована: Окт. 30, 2024
Lower limb length discrepancy (LLD) in children and adolescents, often due to congenital or acquired conditions, is treated achieve equality alignment, optimizing function minimizing cosmetic concerns for an active adulthood. This study evaluated the Health-Related Quality of Life (HRQoL) physical functioning adults who underwent unilateral lengthening with circular external fixators (EFs) childhood.
Язык: Английский
Процитировано
0
Seminars in Colon and Rectal Surgery, Год журнала: 2024, Номер 35(4), С. 101064 - 101064
Опубликована: Ноя. 6, 2024
Язык: Английский
Процитировано
0
PLoS ONE, Год журнала: 2024, Номер 19(11), С. e0314360 - e0314360
Опубликована: Ноя. 21, 2024
Background Chronic conditions are a significant public health concern due to their rising prevalence, association with high mortality, and substantial healthcare costs. General practitioners play crucial role in managing these conditions, quality indicators essential tools for assessing the of care. Electronic feedback reports incorporating indicator performance have shown promise improving care quality. However, most studies focused on single or link financial incentives, which may not sustain long-term practice changes. This study aims evaluate effectiveness multi-condition electronic Swiss general without incentives. Methods randomized controlled trial involves enrolled FIRE project, database medical records from primary Participants receive either plain report comprehensive -specific bi-monthly 12 months. The contains descriptive summaries activities, while indicator-specific includes data 14 across cardiovascular, endocrine, pulmonary, renal domains. were selected multi-step process involving review literature clinical guidelines, domain expert consultations, panel discussion practitioners. objective is compare respect indicators. Conclusion addresses critical gap by evaluating Its findings can inform future policies strategies, line national international initiatives that promote even require implementation measurement activities practice. Trial registration registry: ISRCTN. Registration number: ISRCTN10637092 , https://www.isrctn.com/ISRCTN10637092 . Registered January 9, 2024.
Язык: Английский
Процитировано
0
Journal of Multidisciplinary Healthcare, Год журнала: 2024, Номер Volume 17, С. 5521 - 5570
Опубликована: Ноя. 1, 2024
The aim of this mixed methods systematic review was to synthesize contemporary evidence on effectiveness community-based allied health (AH) services acute care utilizations and views from relevant stakeholders. An a priori protocol registered with PROSPERO [CRD42023437013]. Inclusion criteria were: (a) stand-alone interventions led by practitioners/graduates one or more target AH professions (audiology, exercise physiology, diabetes educator, nutrition dietetics, occupational therapy, physiotherapy, podiatry, psychology, social work, speech pathology); (b) examined utilization-related outcomes with/without perceptions stakeholders; (c) published after 2010 in English. Eligible studies were identified from: bibliographic databases (MEDLINE, Embase, EmCare, PsycINFO, CINAHL complete, the Cochrane Library) (September 19, 2023); online (ProQuest Central ProQuest Dissertations & Theses Global) theses repository (Trove) 20, Google Scholar (October 17-18, (d) citation searching. A modified version McMaster Critical Appraisal Tools McGill Mixed Methods Tool used assess methodological quality. Data synthesis through convergent segregated approach. Certainty assessed using Grading Recommendations, Assessment, Development Evaluation. There 67 included papers. integrated quantitative qualitative findings demonstrated evidence, likely influenced heterogeneity base, for utilizations. Patients their carers largely positive about these services, highlighting opportunities build experiences. certainty patient-important however "very low", emphasizing cautious interpretation. shed light breadth scope community sector, its potential impact sector. Further investment in, ongoing research on, can strengthen primary healthcare relieve pressure
Язык: Английский
Процитировано
0