Prognostic Factors and Overall Survival in Pelvic Ewing's Sarcoma and Chordoma: A Comparative SEER Database Analysis

Heliyon, Год журнала: 2024, Номер 10(17), С. e37013 - e37013

Опубликована: Авг. 28, 2024

Язык: Английский

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Tumor-derived IL-6 promotes chordoma invasion by stimulating tumor-associated macrophages M2 polarization and TNFα secretion

International Immunopharmacology, Год журнала: 2024, Номер 143, С. 113315 - 113315

Опубликована: Окт. 10, 2024

Язык: Английский

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Advances in tumor immunotherapy targeting macrophages

Expert Review of Clinical Immunology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 5, 2024

Introduction In recent years, immunotherapy has shown significant therapeutic potential in patients with advanced tumors. However, only a small number of individuals benefit, mainly due to the tumor microenvironment (TME), which provides conditions for development Macrophages TME, known as tumor-associated macrophages (TAM), are divided into M1 anti-tumor and M2 pro-tumor phenotypes, play regulatory role various stages tumorigenesis, promote tumorigenesis metastasis, cause resistance.

Язык: Английский

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Membrane palmitoylated protein MPP1 inhibits immune escape by regulating the USP12/ CCL5 axis in urothelial carcinoma

International Immunopharmacology, Год журнала: 2024, Номер 146, С. 113802 - 113802

Опубликована: Дек. 18, 2024

Язык: Английский

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Combinatorial therapies for epigenetic, immunotherapeutic, and genetic targeting of chordoma

Journal of Neuro-Oncology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 31, 2024

Язык: Английский

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