An overview of pyridazin-3(2 H )-one: a core for developing bioactive agents targeting cardiovascular diseases and cancer DOI
Zeinab S. Abd-Rabo, Aya M. Serry, Riham F. George

и другие.

Future Medicinal Chemistry, Год журнала: 2024, Номер 16(16), С. 1685 - 1703

Опубликована: Авг. 6, 2024

Cardiovascular diseases (CVDs) and cancer are the top two leading causes of death globally. Vasodilators commonly used to treat various CVDs. In treatment, targeted anticancer agents have been developed minimize side effects compared with traditional chemotherapy. Many hypertension patients more prone cancer, a case known as reverse cardio-oncology. This leads search for drugs dual activity or repurposing strategy discover new therapeutic uses drugs. Recently, medicinal chemists shown great interest in synthesizing pyridazinone derivatives due their significant biological activities tackling these critical health challenges. review will concentrate on pyridazin-3(2

Язык: Английский

An overview of pyridazin-3(2 H )-one: a core for developing bioactive agents targeting cardiovascular diseases and cancer DOI
Zeinab S. Abd-Rabo, Aya M. Serry, Riham F. George

и другие.

Future Medicinal Chemistry, Год журнала: 2024, Номер 16(16), С. 1685 - 1703

Опубликована: Авг. 6, 2024

Cardiovascular diseases (CVDs) and cancer are the top two leading causes of death globally. Vasodilators commonly used to treat various CVDs. In treatment, targeted anticancer agents have been developed minimize side effects compared with traditional chemotherapy. Many hypertension patients more prone cancer, a case known as reverse cardio-oncology. This leads search for drugs dual activity or repurposing strategy discover new therapeutic uses drugs. Recently, medicinal chemists shown great interest in synthesizing pyridazinone derivatives due their significant biological activities tackling these critical health challenges. review will concentrate on pyridazin-3(2

Язык: Английский

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