Impact of de‐branched starch molecules and fatty acid complexes on the attenuation of ageing‐induced cognitive impairment DOI

Xuan Yao,

Anqi Wang, Bo Gao

и другие.

Journal of the Science of Food and Agriculture, Год журнала: 2023, Номер 103(12), С. 5839 - 5848

Опубликована: Май 2, 2023

Ageing and associated cognitive impairments are becoming serious issues around the world. In this study, physiological properties of three kinds complexes fatty acid (capric, stearic oleic acid, respectively) de-branched starch molecules were investigated via a d-galactose-induced ageing model. This study revealed differences in regulation impairment brain damage following intervention different complexes, which might highlight potent approach for prevention chronic disease.Data indicated that improved response time function bio-parameter markers with oxidative stress rats. Among them, prepared from starch-oleic showed greater improvement compared to others. addition, starch-capric complex higher morphology colon cells hippocampal neuronal cells. The consumption -oleic generated more short-chain acids gut. More importantly, complexation either caprate or stearate enhanced gut Akkermansia. Therefore, it was proposed richness Akkermansia metabolites be reduced induced by progress. Moreover, AMPK (AMP-activated protein kinase) pathway activated liver diet. summary, exhibited effect on attenuation ageing-induced impairment.This new intervening during progress food supply. © 2023 Society Chemical Industry.

Язык: Английский

Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity DOI Creative Commons

Aleksandar Martinović,

Matilde Mantovani,

Natalia Trpchevska

и другие.

Frontiers in Aging, Год журнала: 2024, Номер 5

Опубликована: Ноя. 26, 2024

Longevity medicine is an emerging and iterative healthcare discipline focusing on early detection, preventive measures, personalized approaches that aim to extend healthy lifespan promote aging. This comprehensive review introduces the innovative concept of "

Язык: Английский

Процитировано

0
Impact of de‐branched starch molecules and fatty acid complexes on the attenuation of ageing‐induced cognitive impairment DOI

Xuan Yao,

Anqi Wang, Bo Gao

и другие.

Journal of the Science of Food and Agriculture, Год журнала: 2023, Номер 103(12), С. 5839 - 5848

Опубликована: Май 2, 2023

Ageing and associated cognitive impairments are becoming serious issues around the world. In this study, physiological properties of three kinds complexes fatty acid (capric, stearic oleic acid, respectively) de-branched starch molecules were investigated via a d-galactose-induced ageing model. This study revealed differences in regulation impairment brain damage following intervention different complexes, which might highlight potent approach for prevention chronic disease.Data indicated that improved response time function bio-parameter markers with oxidative stress rats. Among them, prepared from starch-oleic showed greater improvement compared to others. addition, starch-capric complex higher morphology colon cells hippocampal neuronal cells. The consumption -oleic generated more short-chain acids gut. More importantly, complexation either caprate or stearate enhanced gut Akkermansia. Therefore, it was proposed richness Akkermansia metabolites be reduced induced by progress. Moreover, AMPK (AMP-activated protein kinase) pathway activated liver diet. summary, exhibited effect on attenuation ageing-induced impairment.This new intervening during progress food supply. © 2023 Society Chemical Industry.

Язык: Английский

Процитировано

0