Fabrication and Characterization of Amphotericin B Loaded Poly(Vinyl Alcohol)/Chitosan‐ZnO Biocomposite Films for Antimicrobial Wound Dressings DOI

Ozlem Ayse Tosyali,

Furkan Şahin, Yüksel Çetin

и другие.

Journal of Applied Polymer Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 14, 2024

ABSTRACT Developing efficient hydrogel‐based wound dressings has gained increasing attention in improved healing capabilities. In this study, the biocomposite hydrogel films consisting of polyvinyl alcohol (PVA), chitosan (CS), and zinc oxide nanoparticles (ZnO NPs) were prepared using solvent casting method. The also loaded (5% w/w) with Amphotericin B (AmB) as a model drug to develop new suitable material potential application high‐performance dressing controlled release. chemical nature, thermal properties, morphology PVA/CS PVA/CS‐ZnO hydrogels analyzed compared by FTIR, TGA, SEM–EDX analysis. effect ZnO NPs on swelling behavior was studied. presented lesser degree ZnO‐free hydrogels. AmB‐loaded exhibited sustained release rate during 72 h PBS at pH 7.4. Biocompatibility all types (with or without AmB) L929 HaCaT cell lines evaluated high viability examined MTT assay. antimicrobial activity against Escherichia coli , Staphylococcus aureus Candida albicans modified AATCC 100 method, whereby R value represents log reduction number surviving colonies. mean values for drug‐free 6.81 E . 6.03 S 6.82 C addition AmB further enhanced activity, 7.16, 6.38, 7.31, demonstrating significant synergistic maximum efficacy. results showed that (PVA/CS‐ZnO‐AmB) can be used material.

Язык: Английский

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings DOI Creative Commons

A. S. Alberts,

Dana-Ionela Tudorache,

Adelina-Gabriela Niculescu

и другие.

Gels, Год журнала: 2025, Номер 11(2), С. 123 - 123

Опубликована: Фев. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Язык: Английский

Процитировано

4

Metallic nanoparticles unveiled: Synthesis, characterization, and their environmental, medicinal, and agricultural applications DOI
Mohammad Tahir Aminzai, Metin Yıldırım, Erdal Yabalak

и другие.

Talanta, Год журнала: 2024, Номер 280, С. 126790 - 126790

Опубликована: Авг. 29, 2024

Язык: Английский

Процитировано

13

Review on application of herbal extracts in biomacromolecules-based nanofibers as wound dressings and skin tissue engineering DOI

Mohaddeseh Sharifi,

S. Hajir Bahrami

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 277, С. 133666 - 133666

Опубликована: Июль 5, 2024

Язык: Английский

Процитировано

7

Synthesis of Hybrid ZnO Nanohexagons and Nanorods with CNT Embedded in PVC Film for Advanced Insulation and Optoelectronic Applications DOI Creative Commons
Mohamed Mohamady Ghobashy, Ahmed A. Zaher, Sameh Khalil

и другие.

ECS Journal of Solid State Science and Technology, Год журнала: 2025, Номер 14(3), С. 031004 - 031004

Опубликована: Фев. 24, 2025

This study focuses on the synthesis, characterization, and application of a novel polyvinyl chloride (PVC)/carbon nanotube (CNT)/zinc oxide (ZnO) hybrid nanocomposite. ZnO nanostructures with two distinct morphologies (nanohexagons nanorods) were synthesized embedded within PVC matrix alongside CNTs to achieve functional composite. TEM analysis revealed presence both nanohexagon nanorod structures CNTs. SEM EDX analyses confirmed uniform distribution matrix. FTIR UV–vis successful integration ZnO, exhibiting well-defined high aspect ratio. The optical properties are characterized by reduction in bandgap from 5.40 eV for PVC/ZnO 4.60 PVC/ZnO/5%CNT, indicating an increase absorption visible spectrum. Furthermore, AC conductivity demonstrates significant frequency dependence, increasing CNT concentration due formation conductive pathways. dielectric constant also shows enhanced values increased content, attributed improved interfacial polarization. simulation electric field reveals that PVC/CNT/ZnO nanocomposite exhibits more than conventional PVC. concludes has potential applications optoelectronics devices.

Язык: Английский

Процитировано

0

Nanoflowers: A multifunctional nanomaterial revolutionizing medicine, environmental protection, and sustainable agriculture DOI
Metin Yıldırım, Mohammad Tahir Aminzai, Erdal Yabalak

и другие.

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114311 - 114311

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Ecofriendly Approaches in nanomaterial synthesis for sustainable healthcare applications DOI Creative Commons

Rajan Verma,

Gaurav Kumar, Viyat Varun Upadhyay

и другие.

E3S Web of Conferences, Год журнала: 2024, Номер 511, С. 01024 - 01024

Опубликована: Янв. 1, 2024

This paper has been formally retracted from publication by the Publisher due to fact that scientific relevance of this work is questionable. Request approved on October 9, 2024.

Язык: Английский

Процитировано

0

In vitro chronic wound healing using collagen and plant extract along with zinc nanoparticles DOI Creative Commons
J. Sofia Bobby,

S. Purnima.,

V Mythily

и другие.

EAI Endorsed Transactions on Pervasive Health and Technology, Год журнала: 2024, Номер 10

Опубликована: Апрель 15, 2024

INTRODUCTION: While the use of zinc nanoparticles (ZnNPs) as an antibacterial agent in biomedical industry has recently attracted significant attention, collagen aroused interest a biomaterial medical and tissue engineering applications. OBJECTIVES: In order to create biofilm loaded with biosynthesized ZnNPs for chronic wound healing applications, type-I was extracted from study's subject. by acid soluble technique, isolated fish skin trevally identified SDS-PAGE. Aqueous extract Cassia fistula leaves also used greenly manufacture stable ZnNPs, which were then characterized UV-Vis, FTIR, XRD measurements. METHODS: Collagen added polyvinyl alcohol (PVA), creating thin that had high biocompatibility due production method's absence chemical reducer crosslinking agent. When tested against harmful bacteria, both alone PVA/Collagen/ZnNPs biofilms showed potent activity. RESULTS: By using MTT test, cytotoxic effects on Vero cell line evaluated. With 97.76% closure, demonstrated strong vitro scratch efficacy. CONCLUSION: The findings show film dramatically increased migration 40.0% at 24 hours, 79.20% 48 74 hours.

Язык: Английский

Процитировано

0

Fabrication and Characterization of Amphotericin B Loaded Poly(Vinyl Alcohol)/Chitosan‐ZnO Biocomposite Films for Antimicrobial Wound Dressings DOI

Ozlem Ayse Tosyali,

Furkan Şahin, Yüksel Çetin

и другие.

Journal of Applied Polymer Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 14, 2024

ABSTRACT Developing efficient hydrogel‐based wound dressings has gained increasing attention in improved healing capabilities. In this study, the biocomposite hydrogel films consisting of polyvinyl alcohol (PVA), chitosan (CS), and zinc oxide nanoparticles (ZnO NPs) were prepared using solvent casting method. The also loaded (5% w/w) with Amphotericin B (AmB) as a model drug to develop new suitable material potential application high‐performance dressing controlled release. chemical nature, thermal properties, morphology PVA/CS PVA/CS‐ZnO hydrogels analyzed compared by FTIR, TGA, SEM–EDX analysis. effect ZnO NPs on swelling behavior was studied. presented lesser degree ZnO‐free hydrogels. AmB‐loaded exhibited sustained release rate during 72 h PBS at pH 7.4. Biocompatibility all types (with or without AmB) L929 HaCaT cell lines evaluated high viability examined MTT assay. antimicrobial activity against Escherichia coli , Staphylococcus aureus Candida albicans modified AATCC 100 method, whereby R value represents log reduction number surviving colonies. mean values for drug‐free 6.81 E . 6.03 S 6.82 C addition AmB further enhanced activity, 7.16, 6.38, 7.31, demonstrating significant synergistic maximum efficacy. results showed that (PVA/CS‐ZnO‐AmB) can be used material.

Язык: Английский

Процитировано

0