Physica Scripta,
Год журнала:
2024,
Номер
99(12), С. 125917 - 125917
Опубликована: Окт. 24, 2024
Abstract
In
this
study,
the
structural
and
optical
characteristics
of
CR-39
films
were
investigated
both
theoretically
experimentally.
A
number
parameters
for
structure
computed
by
density
functional
theory
(DFT)
method
at
B3LYP/6–311
G
(p,
d)
level
theory.
FTIR
UV/Vis
spectroscopy
used
to
determine
compositions
CR39
film,
respectively.
The
experimental
findings
show
good
concordance.
It
was
found
that
compound’s
total
energy,
dipole
moment,
energy
difference
between
LUMO
HOMO
were,
respectively,
−994.575
a.u.,
2.772
Debye,
7.045
eV.
MEP
showed
a
progressive
change
in
color,
with
blue
signifying
low
electron
red
denoting
high
linked
nucleophilic
reactivity
electrophilic
reactivity.
Further,
positive
charges
on
all
hydrogen
atoms,
which
range
from
0.16506
0.22032
imply
they
are
acceptors.
H34
is
strongly
produced
when
electrons
negatively
charged
C17
taken
up.
Because
donor
part
carbon
atoms
negative,
while
other
positive.
highest
electronegative
H23
H24
substituted,
resulting
extremely
negative
atom
C7
(−0.32436).
According
experimentally
determined
absorption
coefficient
gap
values,
may
find
application
optoelectronic
devices.
Gels,
Год журнала:
2025,
Номер
11(5), С. 322 - 322
Опубликована: Апрель 25, 2025
Despite
the
potential
of
film
dressings
for
wound
healing,
many
formulations
lack
an
optimized
design
in
order
to
ensure
that
ingredients
were
carefully
chosen
increase
product’s
efficacy
and
stability,
while
also
ensuring
patient’s
comfort
during
treatment.
Moreover,
commercially
available
do
not
contain
herbal
extracts
or
other
active
substances
with
healing
properties,
highlighting
a
gap
market
need
further
research
this
direction.
The
aim
work
was
development
optimization
bio-inspired
formulation
complex
extract-loaded
film-dressing
be
used
care,
using
quality
by
approach.
After
setting
target
product
profile
critical
attributes
undergoing
risk
assessment,
experiments
implemented.
All
selected
biodegradable,
aligning
current
natural
approach,
based
on
their
biocompatibility
reduced
environmental
impact.
A
D-optimal
experimental
plan
used,
which
types
concentrations
film-forming
agents
plasticizers
varied:
xanthan
gum,
acacia
sodium
carboxymethylcellulose
glycerol,
1,3-propanediol,
xylitol,
respectively.
contained
polyvinyl
alcohol
previously
studied
extract.
films
characterized
terms
uniformity
mass,
thickness,
swelling
degree,
folding
endurance,
adhesive,
mechanical
properties.
achieved
maximizing
adhesive
hardness,
deformation
at
target,
elongation
break.
characterized,
vitro
total
polyphenolic
content
release
from
evaluated.
Following
understanding
influences
factors
characteristics,
composition
determined
as
follows:
5%
alcohol,
0.25%
10%
20%
exhibited
high
degree
(627.28%),
properties
(adhesive
force
28.00
g
adhesiveness
0.20
mJ),
elasticity
(deformation
29.80%,
break
106.90%),
well
good
(hardness
2616.00
g),
are
suitable
characteristics
use
wounds.
sustained
release,
maximum
polyphenols
88.00%
after
8
h.
