Anthropometric and Biochemical Correlations of Insulin Resistance in a Middle-Aged Maltese Caucasian Population
Journal of Nutrition and Metabolism,
Год журнала:
2024,
Номер
2024, С. 1 - 10
Опубликована: Фев. 21, 2024
Insulin
resistance
(IR)
is
associated
with
increased
cardiovascular
disease
risk,
and
all-cause,
cardiovascular,
cancer
mortality.
A
number
of
surrogate
markers
are
used
in
clinical
practice
to
diagnose
IR.
The
aim
this
study
was
investigate
the
discriminatory
power
a
routinely
available
anthropometric
biochemical
variables
predicting
IR
determine
their
optimal
cutoffs.
We
performed
cross-sectional
cohort
middle-aged
individuals.
receiver
operator
characteristics
(ROC)
analyses
order
parameters
interest
detecting
IR,
which
defined
as
homeostatic
model
assessment-insulin
≥2.5.
Both
lipid
accumulation
product
(LAP)
visceral
adiposity
index
(VAI)
exhibited
good
detect
both
males
females.
cutoffs
were
42.5
1.44,
respectively,
36.2
1.41,
Serum
triglycerides
(TG)
waist
circumference
(WC)
similarly
demonstrated
sexes.
for
serum
TG
WC
1.35
mmol/L
96.5
cm,
men
1.33
82
women.
On
other
hand,
systolic
diastolic
blood
pressure,
liver
transaminases,
high-density
lipoprotein
cholesterol,
uric
acid,
ferritin,
waist-hip
ratio,
"A"
body
shape,
thigh
circumference,
weight-adjusted
all
had
poor
power.
Our
data
show
that
LAP,
VAI,
TG,
have
lower
than
those
currently
recommended
Replication
studies
required
different
subpopulations
ethnicities
be
able
update
current
cut
points
ones
reflect
contemporary
population
well
evaluate
longitudinal
relationship
longer-term
cardiometabolic
outcomes.
Язык: Английский
Relationship between the Mediterranean Diet and Vascular Function in Subjects with and without Increased Insulin Resistance
Nutrients,
Год журнала:
2024,
Номер
16(18), С. 3106 - 3106
Опубликована: Сен. 14, 2024
(1)
The
main
aim
of
this
study
was
to
analyze
the
relationship
Mediterranean
diet
(MD)
with
vascular
function
in
participants
and
without
increased
insulin
resistance
(IR)
Spanish
population.
A
secondary
differences
by
gender.
(2)
Methods:
Data
were
analyzed
from
3401
subjects
EVA,
MARK,
EVIDENT
studies
(mean
age
=
60
years
57%
men).
IR
evaluated
triglyceride
glucose
index
(TyG
index).
TyG
Ln
[(fasting
mg/dL
×
fasting
mg/dL)/2].
MD
measured
against
MEDAS
questionnaire,
14
items
used
PREDIMED
study.
Vascular
stiffness
estimated
brachial–ankle
pulse
wave
velocity
(baPWV)
cardio
ankle
(CAVI)
using
Vasera
VS-1500®.
(3)
Results:
mean
value
5.82
±
2.03;
(men:
5.66
2.06;
women:
6.04
1.99;
p
<
0.001).
adherence
36.8%
34.2%;
40.3%;
baPWV
14.39
2.78;
14.50
2.65;
14.25
2.93;
0.005).
≥
14.5
m/s
found
43.4%
43.6%;
40.0%;
0.727).
CAVI
8.59
1.28;
8.75
8.37
1.26;
values
9
present
39.0%
44.4%;
31.7%;
TGC/G
10.93
1.39;
11.08
1.33;
10.73
1.43;
49.9%.
average
score
negatively
associated
all
groups
(<0.05),
except
group
women
resistance.
(4)
Conclusions:
results
suggest
that
is
parameters
studied
Язык: Английский
Exploring the Associations of Neck Circumference, Blood Pressure, CRP, and Insulin Resistance on the Visceral Adiposity Index: Insights from a Cross-Sectional Study
Endocrines,
Год журнала:
2024,
Номер
5(4), С. 538 - 546
Опубликована: Ноя. 20, 2024
Background:
The
visceral
adiposity
index
(VAI)
is
a
composite
marker
designed
to
quantify
and
its
metabolic
implications.
It
integrates
anthropometric
(such
as
waist
circumference
BMI)
parameters
(including
triglyceride
levels
HDL
cholesterol),
providing
more
comprehensive
assessment
of
fat
distribution
than
traditional
measures
alone.
Higher
VAI
values
are
indicative
increased
have
been
linked
heightened
cardiovascular
risk
disturbances.
In
recent
years,
understanding
the
complex
interplay
between
factors
health
has
become
increasingly
important.
Methods:
This
cross-sectional
study
delves
into
influence
neck
(NC),
blood
pressure
(BP),
C-reactive
protein
(CRP),
insulin
resistance
on
among
outpatient
cardiology
patients,
offering
insights
sex-specific
disparities
utility
diagnostic
tool
for
assessing
associated
risks.
Results:
sample
comprised
268
patients
(152
men,
116
women).
Men,
averaging
55.4
years
old
(SD
=
14.4),
exhibited
significantly
higher
women,
with
robust
correlations
found
markers
(Insulin:
ρ
−0.167,
p
0.006;
HOMA-IR:
−0.163,
0.007).
Analysis
across
quartiles
highlighted
distinct
patterns,
revealing
lower
NC
elevated
systolic
(SBP)
in
categories.
Despite
these
associations,
multiple
linear
regression
controlling
age
sex
demonstrated
limited
predictive
capacity
NC,
BP,
CRP,
lipid
profiles
(R2
range:
0.001–0.011).
Conclusions:
These
findings
underscore
suggest
that
serves
modest
yet
valuable
Язык: Английский