Current cannabis use and pain management among US cancer patients
Supportive Care in Cancer,
Год журнала:
2024,
Номер
32(2)
Опубликована: Янв. 18, 2024
Abstract
Background
National
studies
reporting
the
prevalence
of
cannabis
use
have
focused
on
individuals
with
a
history
cancer
without
distinction
by
their
treatment
status,
which
can
impact
symptom
burden.
While
pain
is
primary
motivation
to
in
cancer,
magnitude
its
association
remains
understudied.
Methods
We
examined
and
management
among
5523
respondents
Behavioral
Risk
Factor
Surveillance
System
history.
Survey-weighted
proportions
respondents’
are
reported,
stratified
status.
Regression
models
estimated
odds
ratios
(ORs)
95%
confidence
intervals
(CIs)
cancer-related
use.
Results
Cannabis
was
slightly
more
prevalent
those
undergoing
active
relative
who
were
not
(9.3%
vs.
6.2%;
P
=0.05).
Those
under
likely
medicinally
(71.6%
50.0%;
=0.03).
Relative
pain,
persons
medical
control
(OR
2.1,
CI,
1.4–3.2)
or
uncontrolled
twice
as
2.0,
1.1–3.5).
Conclusions
Use
patients
may
be
related
positively
associated
pain.
Future
research
should
investigate
associations
use,
burden,
regimens
across
spectrum
facilitate
interventions.
Язык: Английский
Prevalence of cannabis and medication use by indices of residential urbanicity and deprivation among Ohio cancer patients
Cancer Causes & Control,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 12, 2025
Abstract
Purpose
There
is
increasing
interest
in
the
use
of
cannabis
products
to
alleviate
symptom
burden
among
cancer
patients.
Although
data
remain
limited,
some
evidence
suggests
that
state
legalization
associated
with
reduced
opioid
use.
Indices
area-level
social
determinants
health
may
provide
insights
into
patterns
symptom-managing
behaviors
context
equity.
Methods
Residential
ZIP
codes
from
854
Ohio
residents
diagnosed
invasive
at
an
academic
center
were
used
assign
rural–urban
commuting
area
(RUCA)
and
deprivation
index
(SDI)
values.
RUCA
was
categorized
as
metropolitan
non-metropolitan,
SDI
dichotomized
median.
Participants
completed
a
one-time
cannabis-focused
questionnaire
which
included
items
on
medications
symptoms.
Results
The
prevalence
self-reported
(19%
vs.
13%)
(30%
21%)
higher
patients
living
areas
disadvantage
lower.
No
differences
observed
for
benzodiazepines
or
any
product
by
residential
urbanicity.
Conclusion
Larger,
multi-institutional
studies
detailed
measurement
increased
capacity
examine
additional
are
needed
confirm
explain
these
descriptive
findings.
Язык: Английский
Cannabis Use and Disclosure in the Oncology Setting: A Cross-Sectional Survey Exploring Information Needs Among Cancer Survivors
Clinical journal of oncology nursing,
Год журнала:
2025,
Номер
29(2), С. 157 - 164
Опубликована: Март 14, 2025
Background:
Given
the
potential
positive
and
negative
impacts
of
cannabis
use
during
cancer
care,
more
information
is
needed
to
understand
how
changes
in
legalization
social
norms
have
affected
clinical
disclosure
among
survivors.Objectives:
The
purpose
this
research
was
explore
behaviors,
disclosure,
needs
survivors.Methods:
study
team
conducted
cross-
sectional
analyses
using
descriptive
statistics
assess
data
collected
via
an
online
survey
distributed
through
health
communities.Findings:
This
analysis
included
719
participants,
most
reported
currently
undergoing
treatment.
About
one-third
current
use.
Cannabis
varied
across
care
continuum,
those
discussed
their
with
a
healthcare
provider
interest
receiving
about
cannabis.
Язык: Английский
Metallothionein Family Proteins as Regulators of Zinc Ions Synergistically Enhance the Anticancer Effect of Cannabidiol in Human Colorectal Cancer Cells
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(23), С. 16621 - 16621
Опубликована: Ноя. 22, 2023
Cannabidiol
(CBD)
is
a
chemical
obtained
from
Cannabis
sativa;
it
has
therapeutic
effects
on
anxiety
and
cognition
anti-inflammatory
properties.
Although
pharmacological
applications
of
CBD
in
many
types
tumors
have
recently
been
reported,
the
mechanism
action
not
yet
fully
understood.
In
this
study,
we
perform
an
mRNA-seq
analysis
to
identify
target
genes
after
determining
cytotoxic
concentrations
using
MTT
assay.
treatment
regulated
expression
related
DNA
repair
cell
division,
with
metallothionein
(MT)
family
being
identified
as
having
highly
increased
levels
induced
by
CBD.
It
was
also
found
that
MT
were
decreased
colorectal
cancer
tissues
compared
those
normal
tissues,
indicating
downregulation
might
be
associated
tumor
progression.
A
qPCR
experiment
revealed
Moreover,
or
crude
extract
but
other
cannabinoids,
suggesting
specifically
synergistic
effect
between
gene
transfection
zinc
ion
found.
conclusion,
novel
could
synergistically
increase
anticancer
activity
regulating
ions
human
cells.
Язык: Английский
Phytochemical Modulation of Ion Channels in Oncologic Symptomatology and Treatment
Cancers,
Год журнала:
2024,
Номер
16(9), С. 1786 - 1786
Опубликована: Май 6, 2024
Modern
chemotherapies
offer
a
broad
approach
to
cancer
treatment
but
eliminate
both
and
non-cancer
cells
indiscriminately
and,
thus,
are
associated
with
host
of
side
effects.
Advances
in
precision
oncology
have
brought
about
new
targeted
therapeutics,
albeit
mostly
limited
subset
patients
an
actionable
mutation.
They
too
come
effects
ultimately,
‘self-resistance’
the
treatment.
There
is
recent
interest
modulation
ion
channels,
transmembrane
proteins
that
regulate
flow
electrically
charged
molecules
out
cells,
as
aid
cancer.
Phytochemicals
been
shown
act
on
channels
high
specificity
regardless
tumor’s
genetic
profile.
This
paper
explores
use
phytochemicals
symptom
management
Язык: Английский
Associations of Cancer Patients' Demographic and Clinical Characteristics With Cannabis-Related Interest and Behaviors
Journal of Palliative Medicine,
Год журнала:
2023,
Номер
27(3), С. 394 - 399
Опубликована: Дек. 29, 2023
Cannabis
interest
and
use
is
increasing
in
the
United
States,
yet
research
on
its
among
cancer
patients
limited.
Язык: Английский
Which came first, the cannabis or the depression?
Preventive Medicine Reports,
Год журнала:
2024,
Номер
38, С. 102613 - 102613
Опубликована: Янв. 21, 2024
Язык: Английский
CBD treatment following early life seizures alters orbitofrontal-striatal signaling during adulthood
Epilepsy & Behavior,
Год журнала:
2024,
Номер
152, С. 109638 - 109638
Опубликована: Фев. 6, 2024
Язык: Английский
Testing the feasibility of mobile ecological momentary assessment for symptom burden and management among metastatic cancer patients
Digital Health,
Год журнала:
2024,
Номер
10
Опубликована: Янв. 1, 2024
Individuals
who
have
metastatic
cancer
experience
substantial
physical
and
psychological
distress
(e.g.,
pain,
depression,
anxiety)
from
their
disease
its
treatment
compared
to
patients
with
less
advanced
disease.
As
the
burden
of
symptoms
varies
over
time,
ecological
momentary
assessment
(EMA)
may
be
used
better
understand
patients'
symptom
trajectories,
complimenting
traditional
longitudinal
data
collection
methods.
However,
few
EMA
in
The
current
study
adds
existing
literature
by
exploring
interrelated,
common
cancer-related
anxiety,
depression
use
cannabis-based
products,
opioid
medications,
other
(nonopioid)
pain
medications
for
anxiety
or
depression.
Язык: Английский
A Scoping Review of Observational Research on Cannabis Use for Symptom Management in HIV and Cancer: Implications for Cannabis Nursing
Journal of Clinical Nursing,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 27, 2024
ABSTRACT
Background
People
with
HIV
have
a
higher
risk
of
developing
non‐AIDS‐defining
cancers
in
older
age,
leading
to
significant
population
living
two
conditions,
and
cancer.
There
is
an
increasing
interest
cannabis
use
for
symptom
management
people
chronic
conditions;
2023,
the
American
Nurses
Association
officially
recognised
nursing
as
specialty
practice
focusing
on
care
individuals
seeking
education/guidance
therapeutic
cannabis,
supporting
urgency
its
research.
However,
scientific
literature
lacks
synthesised
review
focused
populations.
Aim
To
explore
observational
research
among
and/or
cancer
identify
gaps
current
knowledge
inform
future
policy
development.
Methods
Following
Preferred
Reporting
Items
Systematic
Reviews
Meta‐Analyses
Extension
Scoping
(PRISMA‐ScR)
checklist,
search
relevant
articles
was
conducted
databases
PubMed
(
n
=
552),
PsycInfo
204),
CINAHL
164)
Embase
976).
Upon
screening
1738
articles,
142
were
identified
full‐text
51
retained
data
extraction.
Results
more
studies
evaluating
than
no
comorbid
Most
cross‐sectional
limited
metrics
perceived
effectiveness
safety
dosing/mode
delivery
reducing
symptoms.
While
therapy
under
provision
healthcare
providers,
reported
obtaining
information
about
from
friends/family/the
Internet.
Implications
Cannabis
Nursing
This
body
could
be
strengthened
by
rigorous
longitudinal
study
designs
build
causal
relationships
effects
inclusion
reliable
valid
assessment
measures
over
time,
which
facilitates
clinical
guidance
policymaking
nursing.
Patient
or
Public
Contribution
No
patient
public
contribution.
Язык: Английский