Suicide Risk in Alcohol Use Disorders: Literature Review and Study Protocol with Preliminary Data for a Study in Treatment-Seeking Inpatients
Healthcare,
Год журнала:
2025,
Номер
13(5), С. 535 - 535
Опубликована: Фев. 28, 2025
Background/Objectives:
Individuals
with
substance
use
disorders
are
at
risk
of
displaying
suicidal
behavior
suicide
occurring
more
frequently
compared
to
the
general
population.
This
article
gives
an
overview
existing
literature
on
association
disorders,
especially
alcohol
disorder
(AUD),
behavior.
Studies
indicate
that
individuals
AUD
report
a
lifetime
prevalence
40%
for
least
one
instance
attempted
suicide.
They
also
have
10
14
times
higher
Methods:
The
protocol
and
preliminary
data
from
ongoing
study
focused
clinical
correlations
ideation
attempts
in
treatment-seeking
inpatients
presented.
objective
this
is
address
open
questions
regarding
factors
psychiatric
comorbidities
associated
suicidality
patients
AUD.
In
pilot
feasibility
inpatient
rehabilitation
facility
treatment
150
were
examined.
For
assessment,
Beck
Depression
Inventory
(BDI-II),
Symptom
Check-list-90
(SCL-90),
Scale
Suicidal
Experience
Behavior
(SSEV)
used
as
standardized
questionnaires.
addition,
psychosocial
sociodemographic
variables
recorded.
A
total
257
items
surveyed
each
respondent.
statistical
analysis
was
carried
out
using
IBM
SPSS.
Results:
initial
evaluation
indicates
high
number
responders
(90%
response
rate).
Of
participants
surveyed,
50.7%
(N
=
76)
40.7%
61)
had
already
made
attempt.
Even
small
sample
size,
significant,
moderate-to-large
correlation
between
could
be
demonstrated.
Conclusions:
confirms
factor
role
comorbidity,
consequences
AUD,
Gender
outcome
will
studied
larger
700
patients.
Язык: Английский
Connectomics modeling of regional networks of white-matter fractional anisotropy to predict the severity of young adult drinking
Quantitative Imaging in Medicine and Surgery,
Год журнала:
2025,
Номер
15(3), С. 2405 - 2419
Опубликована: Март 1, 2025
Alcohol
use
impacts
brain
structure,
including
white
matter
integrity,
which
can
be
quantified
by
fractional
anisotropy
(FA)
in
diffusion
tensor
imaging
(DTI).
This
study
explored
the
relationship
between
severity
of
alcohol
consumption
and
FA
changes,
its
sex
differences,
young
adults,
using
data
from
Human
Connectome
Project.
We
analyzed
DTI
949
participants
(491
females)
used
principal
component
analysis
(PCA)
15
drinking
metrics
to
quantify
severity.
Connectome-based
predictive
modeling
(CPM)
was
employed
predict
network
values
a
matrix
116×116
regions.
Mediation
analyses
were
conducted
explore
interrelationships
among
networks
identified
CPM,
severity,
rule-breaking
behavior.
Significant
correlations
found
values.
Both
men
women
showed
significant
negative
connectivity
(men:
r=0.15,
P=0.001;
women:
r=0.30,
P<0.001).
Sex
differences
observed
regions
contributing
predictions.
revealed
inter-relationships
features,
The
connectomics
consumption,
incorporating
pathways,
identify
differences.
approach
provides
new
clues
biological
basis
abuse
evaluates
how
these
interact
broader
for
understanding
misuse
comorbidities.
Язык: Английский