The Potential Mechanisms of Arrhythmia in Coronavirus disease-2019
International Journal of Medical Sciences,
Год журнала:
2024,
Номер
21(7), С. 1366 - 1377
Опубликована: Янв. 1, 2024
Severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2)
leads
to
coronavirus
disease-2019
(COVID-19)
which
can
cause
severe
cardiovascular
complications
including
myocardial
injury,
arrhythmias,
coronary
and
others.Among
these
complications,
arrhythmias
are
considered
serious
life-threatening.Although
have
been
associated
with
factors
such
as
direct
virus
invasion
leading
myocarditis,
immune
response
disorder,
cytokine
storms,
ischemia/hypoxia,
electrolyte
abnormalities,
intravascular
volume
imbalances,
drug
interactions,
side
effects
of
COVID-19
vaccines
autonomic
nervous
system
dysfunction,
the
exact
mechanisms
arrhythmic
in
patients
complex
not
well
understood.In
present
review,
literature
was
extensively
searched
investigate
potential
COVID-19.The
aim
current
review
is
provide
clinicians
a
comprehensive
foundation
for
prevention
treatment
long
COVID-19.
Язык: Английский
SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs
EP Europace,
Год журнала:
2024,
Номер
26(10)
Опубликована: Окт. 1, 2024
Coronavirus
disease
2019
(COVID-19),
caused
by
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2),
has
been
linked
to
cardiovascular
complications,
notably
cardiac
arrhythmias.
The
open
reading
frame
(ORF)
3a
of
the
genome
encodes
for
a
transmembrane
protein
that
can
function
as
an
ion
channel.
aim
this
study
was
investigate
role
SARS-CoV-2
ORF
in
COVID-19-associated
arrhythmias
and
its
potential
pharmacological
target.
Язык: Английский
MICROCIRCULATORY ALTERATIONS IN STABLE CORONARY ARTERY DISEASE PATIENTS WITH CONCOMITANT COVID-19
Wiadomości Lekarskie,
Год журнала:
2023,
Номер
76(10), С. 2224 - 2238
Опубликована: Янв. 1, 2023
The
aim:
To
evaluate
the
alterations
in
microcirculation
of
stable
coronary
artery
disease
(SCAD)
patients
with
concomitant
COVID-19.Materials
and
methods:
cross-sectional
study
analyzed
data
from
80
patients,
being
subdivided
as
follows:
group
1
(G1)
-
SCAD
without
COVID-19
(n=30);
2
(G2)
(n=25);
3
(G3)
(n=25).
control
included
30
relatively
healthy
volunteers.
state
was
assessed
by
nailfold
videocapillaroscopy
(NVC)
laser
Doppler
flowmetry
(LDF).Results:
NVC
G2
revealed
sings
capillary
bed
remodeling,
along
most
pronounced
decrease
(arteriolar
part
loop)
blood
flow
velocity
(vs.
G1
G3).
LDF
were
evident
for
both
endothelium-dependent
-independent
mechanisms
microvascular
regulation.
72
%
constituted
cases
microcirculatory
hemodynamic
«congestion-stasis»
(MHCS)
type
(characterized
decreased
perfusion
index
reduced
reactivity
[MVR]),
mixed
MVR.
pooled
hyporeactive
profile
(of
MHCS
a
MVR)
demonstrated
higher
frequency
(40
%),
against
11
alternative
(p<0,001)
(included
preserved
MVR).Conclusions:
predomination
possessing
or
presented
to
greater
extent,
than
predominantly
Язык: Английский
Postrecovery COVID-19 and interlinking diabetes and cardiovascular events
Elsevier eBooks,
Год журнала:
2024,
Номер
unknown, С. 377 - 382
Опубликована: Янв. 1, 2024
Язык: Английский
Alterations in plasma proteome during acute COVID-19 and recovery
Molecular Medicine,
Год журнала:
2024,
Номер
30(1)
Опубликована: Авг. 25, 2024
Abstract
Background
The
severe
course
of
COVID-19
causes
cardiovascular
injuries,
although
the
mechanisms
involved
are
still
not
fully
recognized,
linked,
and
understood.
Their
characterization
is
great
importance
with
establishment
conception
post-acute
sequelae
COVID-19,
referred
to
as
long
COVID,
where
blood
clotting
endothelial
abnormalities
believed
be
key
pathomechanisms
driving
circulatory
system
impairment.
Methods
presented
study
investigates
temporal
changes
in
plasma
proteins
patients
during
hospitalization
due
SARS-CoV-2
infection
six
months
after
recovery
by
targeted
SureQuant
acquisition
using
PQ500
panel.
Results
In
total,
we
identified
167
that
were
differentially
regulated
between
follow-up
hospitalization,
which
functionally
aggregated
into
immune
activation,
complement
coagulation
cascades,
interleukins
signalling,
platelet
extracellular
matrix
organization.
Furthermore,
found
quantitative
acute
phase
correlate
selected
clinical
characteristics
patients.
Conclusions
In-depth
proteome
investigation
evidenced
substantial
protein
composition
recovering
from
evidencing
a
wide
range
functional
pathways
induced
infection.
addition,
show
subset
proteins,
cascade
regulators
lipoproteins
could
have
value
potential
predictors
long-term
events
convalescents.
Язык: Английский
COVID-19 and the Cardiovascular System: Requiem for a Medical Minotaur
Circulation Research,
Год журнала:
2023,
Номер
132(10), С. 1255 - 1258
Опубликована: Май 11, 2023
Язык: Английский
Malignant Arrhythmia and Cardiac Arrest in the Operating Room
Mohd Husni Alqutamy,
Anwar Dhawi Almutairi,
Mahmoud Rashad Khairi
и другие.
Journal Of Advanced Zoology,
Год журнала:
2023,
Номер
44(S6), С. 1265 - 1273
Опубликована: Дек. 2, 2023
Malignant
arrhythmias
and
cardiac
arrest
in
the
operating
room
are
critical
events
that
pose
significant
risks
to
patient
safety
outcomes.
This
research
paper
aims
provide
a
comprehensive
review
of
current
literature
on
incidence,
risk
factors,
management
malignant
room.
The
will
also
explore
potential
role
advanced
monitoring
early
detection
systems
improving
timely
recognition
these
life-threatening
events.
Additionally,
discuss
arrhythmia
thoroughly
as
definitions.
Ultimately,
findings
this
contribute
better
understanding
challenges
opportunities
addressing
room,
with
goal
Язык: Английский