A cross-sectional study investigating the L-shaped relationship between urinary albumin creatinine ratio and overweight/obesity in children and adolescents DOI Creative Commons
Zhengjiu Cui, Xiaorui Chen, Shengchun Zhai

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 26, 2025

Childhood and adolescent obesity has become one of the most serious public health problems worldwide, may have potential effects on kidney health. The urinary albumin creatinine ratio (UACR) is a sensitive indicator for assessing renal impairment. Relevant studies pediatric populations are more limited controversial. This study aimed to clarify relationship between UACR overweight/obesity in children adolescents United States, thereby providing new insights recommendations clinical management prevention disease. utilized data from National Health Nutrition Examination Survey (NHANES) 2011 2016. Variables were derived demographic, examination, laboratory data. Overweight/obesity status was assessed using BMI criteria, random urine samples used measure UACR. association descriptive statistics, multivariate logistic regression analysis, subgroup curve-fitting analysis. In this 4116 participants aged 8-19, analysis revealed significant negative (OR = 0.32; 95% CI 0.26-0.38; P < 0.001). interaction P-values all greater than 0.05 subgroups, indicating that findings very stable consistent subgroups. addition, smoothed curve fitting threshold effect analyses nonlinear overweight/obesity, with an inflection point log(UACR) determined be 1.435 mg/g. suggest correlation populations. Until precise mechanism found, maintaining standard range age groups reduce incidence albuminuria population.

Язык: Английский

Introduction to the Compendium on Lifelong Care in Women: Applying a Sex- and Gender-Lens to Practice DOI
Kathryn J. Lindley

Circulation Research, Год журнала: 2025, Номер 136(6), С. 551 - 552

Опубликована: Март 13, 2025

Язык: Английский

Процитировано

0
Medical versus surgically-induced weight loss differences on cardiovascular outcomes DOI
Victoria Catalán, Javier Gómez‐Ambrosi, Gema Frühbeck

и другие.

Trends in Cardiovascular Medicine, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
A cross-sectional study investigating the L-shaped relationship between urinary albumin creatinine ratio and overweight/obesity in children and adolescents DOI Creative Commons
Zhengjiu Cui, Xiaorui Chen, Shengchun Zhai

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 26, 2025

Childhood and adolescent obesity has become one of the most serious public health problems worldwide, may have potential effects on kidney health. The urinary albumin creatinine ratio (UACR) is a sensitive indicator for assessing renal impairment. Relevant studies pediatric populations are more limited controversial. This study aimed to clarify relationship between UACR overweight/obesity in children adolescents United States, thereby providing new insights recommendations clinical management prevention disease. utilized data from National Health Nutrition Examination Survey (NHANES) 2011 2016. Variables were derived demographic, examination, laboratory data. Overweight/obesity status was assessed using BMI criteria, random urine samples used measure UACR. association descriptive statistics, multivariate logistic regression analysis, subgroup curve-fitting analysis. In this 4116 participants aged 8-19, analysis revealed significant negative (OR = 0.32; 95% CI 0.26-0.38; P < 0.001). interaction P-values all greater than 0.05 subgroups, indicating that findings very stable consistent subgroups. addition, smoothed curve fitting threshold effect analyses nonlinear overweight/obesity, with an inflection point log(UACR) determined be 1.435 mg/g. suggest correlation populations. Until precise mechanism found, maintaining standard range age groups reduce incidence albuminuria population.

Язык: Английский

Процитировано

0