Biomechanics and Modeling in Mechanobiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 26, 2024
An
ascending
aortic
aneurysm
is
an
often
asymptomatic
localized
dilatation
of
the
aorta.
Aortic
rupture
a
life-threatening
event
that
occurs
when
stress
on
wall
exceeds
its
mechanical
strength.
Therefore,
patient-specific
finite
element
models
could
play
important
role
in
estimating
risk
rupture.
This
requires
not
only
geometry
aorta
but
also
nonlinear
anisotropic
properties
tissue.
In
this
study,
we
presented
methodology
to
estimate
from
magnetic
resonance
imaging
(MRI).
As
theoretical
framework,
used
which
added
noise
simulate
clinical
data
real
patient
and
different
healthy
aneurysmal
tissues
collected
literature.
The
proposed
considered
properties,
zero
pressure
geometry,
heart
motion,
external
tissue
support.
addition,
analyzed
as
homogeneous
material
heterogeneous
model
with
for
descending
parts.
was
applied
pre-surgical,in
vivo
MRI
who
underwent
surgery
during
sample
obtained.
results
were
compared
those
obtained
ex
biaxial
test
patient's
sample.
showed
promising
after
successfully
recovering
all
cases.
study
demonstrates
variable
optimization
process
can
affect
result.
particular,
variables
such
principal
strains
found
obtain
more
realistic
materials
than
displacement
field.
Diagnostics,
Год журнала:
2024,
Номер
14(17), С. 1947 - 1947
Опубликована: Сен. 3, 2024
Aging
affects
the
cardiovascular
system,
and
this
process
may
be
accelerated
in
individuals
with
risk
factors.
The
main
vascular
changes
include
arterial
wall
thickening,
calcification,
stiffening,
together
aortic
dilatation
elongation.
With
aging,
we
can
observe
left
ventricular
hypertrophy
myocardial
fibrosis
atrial
dilatation.
These
lead
to
heart
failure
fibrillation.
Using
multimodality
imaging,
including
ultrasound,
computed
tomography
(CT),
magnetic
resonance
it
is
possible
detect
these
changes.
Additionally,
mainly
via
CT
measurements
of
coronary
artery
calcium
or
ultrasound
carotid
intima-media
thickness,
enables
advanced
stratification
helps
decision-making
about
preventive
strategies.
focus
manuscript
briefly
review
that
occur
as
well
describe
how
imaging
used
for
assessment
asymptomatic
individuals.
Biomechanics and Modeling in Mechanobiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 26, 2024
An
ascending
aortic
aneurysm
is
an
often
asymptomatic
localized
dilatation
of
the
aorta.
Aortic
rupture
a
life-threatening
event
that
occurs
when
stress
on
wall
exceeds
its
mechanical
strength.
Therefore,
patient-specific
finite
element
models
could
play
important
role
in
estimating
risk
rupture.
This
requires
not
only
geometry
aorta
but
also
nonlinear
anisotropic
properties
tissue.
In
this
study,
we
presented
methodology
to
estimate
from
magnetic
resonance
imaging
(MRI).
As
theoretical
framework,
used
which
added
noise
simulate
clinical
data
real
patient
and
different
healthy
aneurysmal
tissues
collected
literature.
The
proposed
considered
properties,
zero
pressure
geometry,
heart
motion,
external
tissue
support.
addition,
analyzed
as
homogeneous
material
heterogeneous
model
with
for
descending
parts.
was
applied
pre-surgical,in
vivo
MRI
who
underwent
surgery
during
sample
obtained.
results
were
compared
those
obtained
ex
biaxial
test
patient's
sample.
showed
promising
after
successfully
recovering
all
cases.
study
demonstrates
variable
optimization
process
can
affect
result.
particular,
variables
such
principal
strains
found
obtain
more
realistic
materials
than
displacement
field.
