Application of emerging technologies in ischemic stroke: from clinical study to basic research DOI Creative Commons
Qiuyan Chen, Shuxia Zhang, Wenxiu Liu

и другие.

Frontiers in Neurology, Год журнала: 2024, Номер 15

Опубликована: Июнь 10, 2024

Stroke is a primary cause of noncommunicable disease-related death and disability worldwide. The most common form, ischemic stroke, increasing in incidence resulting significant burden on patients society. Urgent action thus needed to address preventable risk factors improve treatment methods. This review examines emerging technologies used the management including neuroimaging, regenerative medicine, biology, nanomedicine, highlighting their benefits, clinical applications, limitations. Additionally, we suggest strategies for technological development prevention, diagnosis, stroke.

Язык: Английский

Recent applications of EEG-based brain-computer-interface in the medical field DOI Creative Commons
Xiuyun Liu, Wenlong Wang, Miao Liu

и другие.

Military Medical Research, Год журнала: 2025, Номер 12(1)

Опубликована: Март 24, 2025

Abstract Brain-computer interfaces (BCIs) represent an emerging technology that facilitates direct communication between the brain and external devices. In recent years, numerous review articles have explored various aspects of BCIs, including their fundamental principles, technical advancements, applications in specific domains. However, these reviews often focus on signal processing, hardware development, or limited such as motor rehabilitation communication. This paper aims to offer a comprehensive electroencephalogram (EEG)-based BCI medical field across 8 critical areas, encompassing rehabilitation, daily communication, epilepsy, cerebral resuscitation, sleep, neurodegenerative diseases, anesthesiology, emotion recognition. Moreover, current challenges future trends BCIs were also discussed, personal privacy ethical concerns, network security vulnerabilities, safety issues, biocompatibility.

Язык: Английский

Процитировано

4

Trans-arterial approach for neural recording and stimulation: Present and future DOI
Jian Li,

Xinjian Yang,

Basel Musmar

и другие.

Journal of Clinical Neuroscience, Год журнала: 2025, Номер 135, С. 111180 - 111180

Опубликована: Март 29, 2025

Язык: Английский

Процитировано

1

A wireless, 60-channel, AI-enabled neurostimulation platform DOI Open Access
Daniel S. Rizzuto, Zhe Hu,

Daniel Utin

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Фев. 6, 2025

Abstract Electrical stimulation of the human brain has emerged as a powerful therapeutic modality, enabling alteration neural circuits underlying cognition and behavior. Recent evidence indicates that stimulation’s effects on physiology behavior depend endogenous variation in state, measured by field-potential recordings. Here, we describe 60-channel brain-computer interface – Smart Neurostimulation System (SNS) combines closed-loop analysis spectral features field potential with multi-channel capabilities. We demonstrate system functionality via bench tests from an vivo ovine study exercising subset device’s functionality. Our shows SNS can reliably measure correlates (motion) physiological stimulation. safety histology following 120-day study.

Язык: Английский

Процитировано

0

Brain–computer interfaces in 2023–2024 DOI Creative Commons
Shugeng Chen, Mingyi Chen, Xu Wang

и другие.

Brain‐X, Год журнала: 2025, Номер 3(1)

Опубликована: Март 1, 2025

Abstract Brain–computer interfaces (BCIs) have advanced at a rapid pace in recent years, particularly the medical domain. This review provides comprehensive summary of progress made BCIs during 2023–2024 period, covering wide range topics from invasive to non‐invasive techniques, and fundamental mechanisms clinical applications. The period saw numerous research breakthroughs applications BCI technology. As hardware software continue evolve, as understanding basic principles deepens, expectation is that innovative inventions will increasingly be introduced practice. Both technologies are paving way for broader It anticipated offer greater hope disease treatment, provide additional methods enhancing human bodily functions, ultimately improve quality life.

Язык: Английский

Процитировано

0

Advances in Endovascular Brain Computer Interface: systematic review and future implications DOI Creative Commons
Julien Ognard,

Gerard El Hajj,

Onam Verma

и другие.

Journal of Neuroscience Methods, Год журнала: 2025, Номер 420, С. 110471 - 110471

Опубликована: Май 10, 2025

Brain-computer interfaces (BCIs) translate neural activity into real-world commands. While traditional invasive BCIs necessitate craniotomy, endovascular offer a minimally alternative using the venous system for electrode placement. This systematic review evaluates technical feasibility, safety, and clinical outcomes of BCIs, discussing their future implications. A was conducted per PRISMA guidelines. The search spanned PubMed, Web Science, Scopus databases keywords related to approaches. Studies were included if they reported on in preclinical or settings. Dual independent screening extraction focused material, recording capabilities, safety parameters, efficacy. From 1385 initial publications, 26 met inclusion criteria. Seventeen studies investigated Stentrode device. Among 24 studies, 16 used ovine rodent models, 9 addressed engineering simulation aspects. Two six ALS patients successfully an BCI digital communication. Preclinical data established model, demonstrating stable recordings vascular changes with long-term implantation. Key challenges include thrombosis risk, stability, anatomical variability. Endovascular reduced invasiveness, improved profiles, comparable fidelity methods, promising preliminary severely paralyzed patients. Early results are promising, but remain scarce. Further research is needed optimize signal processing, enhance biocompatibility, refine procedures broader applications.

Язык: Английский

Процитировано

0

Superior cortical venous anatomy for endovascular device implantation: a systematic review DOI
Jamie Brannigan, Alexander McClanahan, Ferdinand Hui

и другие.

Journal of NeuroInterventional Surgery, Год журнала: 2024, Номер unknown, С. jnis - 021434

Опубликована: Март 27, 2024

Endovascular electrode arrays provide a minimally invasive approach to access intracranial structures for neural recording and stimulation. These are currently used as brain-computer interfaces (BCIs) deployed within the superior sagittal sinus (SSS), although cortical vein implantation could improve quality quantity of recorded signals. However, anatomy veins is heterogenous poorly characterised. MEDLINE Embase databases were systematically searched from inception December 15, 2023 studies describing veins. A total 28 included: 19 cross-sectional imaging studies, six cadaveric one intraoperative anatomical study review. There was substantial variability in diameter, length, confluence angle, location relative underlying cortex. The mean number SSS branches ranged 11 45. Trolard most often reported largest vein, with diameter ranging 2.1 mm 3.3 mm. identified posterior central sulcus. One found significant age-related another myoendothelial sphincters at base Cortical data limited inconsistent. tributary SSS; however, its relation cortex variable. Variability may necessitate individualized pre-procedural planning training decoding endovascular BCI. Future focus on cortex, sulcal vessels, vessel wall required.

Язык: Английский

Процитировано

2

Toward an interventional science of recovery after coma DOI Creative Commons
Nicholas D. Schiff

Neuron, Год журнала: 2024, Номер 112(10), С. 1595 - 1610

Опубликована: Май 1, 2024

Recovery of consciousness after coma remains one the most challenging areas for accurate diagnosis and effective therapeutic engagement in clinical neurosciences. depends on preservation neuronal integrity evolving changes network function that re-establish environmental responsiveness. It typically occurs defined steps: it begins with eye opening unresponsiveness a vegetative state, then limited recovery responsiveness characterizes minimally conscious this is followed by reliable communication. This review considers several points novel interventions, example, persons cognitive motor dissociation whom hidden reserve revealed. Circuit mechanisms underlying restoration behavioral communication are discussed. An emerging theme possibility to rescue latent capacities partially damaged human networks across time. These opportunities should be exploited achieve individualized solutions interaction varying levels recovery.

Язык: Английский

Процитировано

1

Alzheimer’s disease and other memory disorders in the age of AI: reflection and perspectives on the 120th anniversary of the birth of Dr. John von Neumann DOI
F. Deák

GeroScience, Год журнала: 2024, Номер unknown

Опубликована: Окт. 17, 2024

Язык: Английский

Процитировано

1

Invasive Brain-Computer Interfaces: 25 Years Of Clinical Trials, Scientific And Practical Issues DOI Creative Commons
О. А. Мокиенко

Annals of the Russian academy of medical sciences, Год журнала: 2024, Номер unknown

Опубликована: Дек. 28, 2024

Brain-computer interfaces (BCIs) provide direct information exchange between the brain and a computer. In invasive BCIs, electrodes are placed intracranially for more accurate faster data external devices. The primary medical objective of these technologies is to compensate motor or speech function in patients with tetraparesis anarthria. recent years, emergence new neuroimplants BCIs results demonstrated clinical trials have led notable increase interest systems from scientific community, investors, public. This review compares different types analyzes discusses achievements unsolved problems application neurotechnologies, as well possible consequences risks their wider use.

Язык: Английский

Процитировано

0

Editorial: Opening a new era in aging and rehabilitation research DOI Creative Commons
Xianwei Zeng,

Maoquan Su,

Hui‐Liang Li

и другие.

Deleted Journal, Год журнала: 2024, Номер 1(1), С. 1 - 3

Опубликована: Март 1, 2024

The global population is increasingly aging, a trend most prominent in societies characterized by high life expectancy and low fertility rates.1 Projections suggest that 2050, 1 5 people will be elderly, marking the first time history older surpass youth demographic.1 Research Lutz et al2 indicates pace of aging likely accelerate coming decades before slowing down around mid-century regions. implications this demographic shift are significant. Notably, failing to address issue can lead decreased state budget stability negatively affect country's economic prosperity.3 In China, particularly striking. Data from seventh national census revealed last decade, proportion aged over 60 65 has risen 5.44% (from 13.26% 2010 18.70% 2020) 4.6% 8.9% 13.5%), respectively.4 Furthermore, research Chen al5 predicts significant increases China's indicators between 2019 2044. rate projected rise 13.24 percentage points, elderly dependency ratio 24.21 oldest-old coefficient 8.33 median age 8.47 years. imminent steep set significantly increase demand for specialized services, including health care, recreation, housing, nutrition.6 This surge number individuals exerting considerable pressure on social security systems worldwide. As result, several countries reevaluating their pension care policies, which advanced economies constitute up 40% all government expenditure.7 Aging at biological level accumulation various molecular cellular damages time, leading progressive decline physical mental capacities, an increased risk diseases, ultimately, death. senescent cells during contributes onset age-related disorders chronic diseases such as atherosclerosis, type 2 diabetes, stroke, cancer.8 age, prevalence rises, adversely affecting individuals' increasing likelihood disabilities. Rehabilitation services play crucial role mitigating these A assessment rehabilitation needs 3 (~2.4 billion globally) could benefit some point lives. underscores need reconsider not niche specialty but critical, widely applicable service.9 vital component universal coverage, complementing promotion, disease prevention, curative palliative services. They enable ages—children, adults, elderly—to gain or regain independence daily activities. includes participating education, work, recreational activities fulfilling important roles family care. Because evolving trends shifts, coupled with rising disabilities, substantially. However, many regions, low-income middle-income countries, growing being adequately met. Over half those needing areas do receive them. reasons unmet multifaceted, including: Lack priorities: Many prioritize policies plans. Financial barriers: High out-of-pocket costs insufficient funding channels make inaccessible many. Shortage professionals: There lack trained professionals field Resource deficits: Inadequate availability assistive technology, equipment, consumables hampers service delivery. Insufficient data: comprehensive data Inefficient referral systems: Referral pathways often inefficient underutilized. Addressing challenges essential ensure meet effectively. To fully harness potential approach strengthening essential. strategy entails integrating levels system ensuring inclusion coverage.10 Recognizing need, World Health Organization (WHO) launched "Rehabilitation 2030" initiative 2017 https://www.who.int/initiatives/rehabilitation-2030. urgency fortifying calls collaboration achieve key objectives: Enhanced leadership management: Elevating within systems' management structures. Development multidisciplinary workforce: Fostering skilled diverse workforce capable addressing complex rehabilitation. Increased services: Securing more financial resources expand improve Improved Collection Research: Enhancing collection promoting inform optimize parallel, WHO also established Alliance. body plays pivotal supporting initiative, primarily through extensive publicity advocacy efforts.11 Alliance's main focus advocate fundamental integral achieving coverage.12,13 Advances new technology have greatly Brain-computer interface (BCI) started 50 years ago, shows great rehabilitation.14,15 BCI, especially stroke spinal cord injuries, offers unparalleled advantages. systematic review illustrates utility BCI restoration upper extremity lower motor function patients supports further investigation other clinical indications.16 Endovascular arrays present novel form minimally invasive devices been deployed human subjects early feasibility studies.17 patient injury, Lorach al18 restored communication brain region digital bridge enabled individual tetraplegia stand walk naturally community settings. Journal (JAR), based China outreach, specializes fields professional journal committed publishing array scholarly content, original research, articles, editorials, centered geriatrics medicine. JAR poised escalating rehabilitation, delving into gerontology, biology pathophysiology diseases. importance innovative solutions, welcomes studies therapies methods conditions, encompassing spans animal models tissue studies. At heart JAR's mission aim enhance quality discovering disseminating targeted treatments methodologies. prioritizes content holds immediate relevance clinicians, physicians, policymakers, our contributions timely impactful. Understanding value perspectives, extends explicit invitation researchers, practitioners, policymakers corners globe contribute findings insights. We keen voices underrepresented regions communities, underscoring commitment broad, inclusive view landscape. Amid burgeoning enhancing extending lifespan. Our only embrace fostering effective approaches field. recognizes richness different cultural backgrounds bring practices, engagement, policy development. provide platform where unique insights just welcomed seen driving innovation actively encourage collaborations geographical divides, understanding partnerships keystones groundbreaking inventive solutions. line this, dedicated inclusivity, offering support authors who may face barriers publication, language differences resources. open-access journal, proud announce years, charged any article processing fees, making it easier heard. testament values amplifies perspectives research. summary, beyond traditional dissemination. building vibrant, community, uniting shape future Statements ethics None. Conflict interest declare they no conflict regard report. Funding source source. statement Please contact corresponding author (Pro. Zeng) request. Author X.Z.: acquisition data; analysis interpretation drafting manuscript; Critical revision manuscript intellectual content: Huiliang Li; Li: statistical analysis; study supervision: Li.

Язык: Английский

Процитировано

0