Verbal working memory and syntactic comprehension segregate into the dorsal and ventral streams, respectively DOI Creative Commons
William Matchin,

Zeinab Khoshhal Mollasaraei,

Leonardo Bonilha

и другие.

Brain Communications, Год журнала: 2024, Номер 6(6)

Опубликована: Янв. 1, 2024

Abstract Syntactic processing and verbal working memory are both essential components to sentence comprehension. Nonetheless, the separability of these systems in brain remains unclear. To address this issue, we performed causal-inference analyses based on lesion connectome network mapping using MRI behavioural testing two groups individuals with chronic post-stroke aphasia. We employed a rhyme judgement task heavy load without articulatory confounds, controlling for overall ability match auditory words pictures perform metalinguistic judgement, isolating effect (103 individuals). assessed non-canonical comprehension, syntactic by incorporating residual performance as covariate (78 Voxel-based structural connectome-based symptom total volume were performed, permutation correct multiple comparisons (4000 permutations). observed that effects localized dorsal stream damage: posterior temporal-parietal lesions frontal-parietal white matter disconnections. These differentiated from comprehension deficits, which primarily associated ventral temporal lobe disconnections, particularly when measure covariate. Our results support conclusion distinct networks, largely loading onto streams, respectively.

Язык: Английский

Grammatical Parallelism in Aphasia: A Lesion-Symptom Mapping Study DOI Creative Commons
William Matchin, Dirk‐Bart den Ouden, Alexandra Basilakos

и другие.

Neurobiology of Language, Год журнала: 2023, Номер 4(4), С. 550 - 574

Опубликована: Янв. 1, 2023

Abstract Sentence structure, or syntax, is potentially a uniquely creative aspect of the human mind. Neuropsychological experiments in 1970s suggested parallel syntactic production and comprehension deficits agrammatic Broca’s aphasia, thought to result from damage mechanisms area left frontal lobe. This hypothesis was sometimes termed overarching agrammatism, converging with developments linguistic theory concerning central supporting language comprehension. However, evidence an association among receptive deficits, expressive cortex equivocal. In addition, relationship distinct grammatical deficit paragrammatism, syntax has not been assessed. We used lesion-symptom mapping three partially overlapping groups left-hemisphere stroke patients investigate these issues: primary group 53 subjects larger sample sizes (N = 130, 218) that overlapped group. Paragrammatic were significantly associated multiple analyses comprehension, particularly when incorporating lesion volume as covariate, but not. The correlates impaired performance temporal lobe regions, which also implicated inferior middle regions agrammatism. Our results provide strong against agrammatism hypothesis. By contrast, our suggest possibility alternative parallelism rooted paragrammatism system posterior

Язык: Английский

Процитировано

10
The language network is topographically diverse and driven by rapid syntactic inferences DOI Creative Commons
Elliot Murphy, Oscar Woolnough

Nature reviews. Neuroscience, Год журнала: 2024, Номер 25(10), С. 705 - 705

Опубликована: Авг. 9, 2024

The language network is topographically

Язык: Английский

Процитировано

3
The neurobiology of sentence production: A narrative review and meta-analysis DOI Creative Commons
Jeremy Yeaton

Brain and Language, Год журнала: 2025, Номер 264, С. 105549 - 105549

Опубликована: Фев. 20, 2025

Although there is a sizeable body of literature on sentence comprehension and processing both in healthy disordered language users, the production remains much more sparse. Linguistic computational descriptions expressive syntactic deficits aphasia are especially rare. In addition, neuroimaging (psycho) linguistic literatures operate largely separately. this paper, I will first lay out theoretical land with regard to psycholinguistic models production. then provide brief narrative overview large-scale meta-analysis as it pertains computation, followed by an attempt integrate findings from functional clinical neuroimaging. Finally, surrounding propose path forward close some existing gaps.

Язык: Английский

Процитировано

0
Multiple dimensions of syntactic structure are resolved earliest in posterior temporal cortex DOI
Elliot Murphy, Patrick S. Rollo, Katrien Segaert

и другие.

Progress in Neurobiology, Год журнала: 2024, Номер 241, С. 102669 - 102669

Опубликована: Сен. 25, 2024

Язык: Английский

Процитировано

2
Verbal short term memory contribution to sentence comprehension decreases with increasing syntactic complexity in people with aphasia DOI Creative Commons
Hellmuth Obrig,

Frank Regenbrecht,

Danièle Pino

и другие.

NeuroImage, Год журнала: 2024, Номер 297, С. 120730 - 120730

Опубликована: Июль 14, 2024

Sentence comprehension requires the integration of linguistic units presented in a temporal sequence based on non-linear underlying syntactic structure. While it is uncontroversial that storage mandatory for this process, there are opposing views regarding relevance general short-term-/working-memory capacities (STM/WM) versus language specific resources. Here we report results from 43 participants with an acquired brain lesion extended left hemispheric network and resulting deficits, who performed sentence-to-picture matching task experimental assessing phonological short-term memory. The sentence systematically varied complexity (embedding depth argument order) while lengths, number propositions plausibility were kept constant. Clinical data including digit-/ block-spans size site additionally used analyses. Correlational analyses confirm performance STM/WM-tasks (experimental digit-span) only two relevant predictors correct sentence-picture-matching, reaction times depended age size. Notably increasing reduced correlational strength speaking additional recruitment resources independent more verbal STM/WM capacities, when resolving complex complementary lesion-behaviour analysis yielded different volumes correlating either sentence-task or STM-task. Factoring out STM measures lesions anterior lobe correlated larger decrease accuracy complexity. We conclude overall depends capacity, increases tax another cognitive resource.

Язык: Английский

Процитировано

1
Brain and grammar: revealing electrophysiological basic structures with competing statistical models DOI
Andrea Cometa, Chiara Battaglini, Fiorenzo Artoni

и другие.

Cerebral Cortex, Год журнала: 2024, Номер 34(8)

Опубликована: Авг. 1, 2024

Abstract Acoustic, lexical, and syntactic information are simultaneously processed in the brain requiring complex strategies to distinguish their electrophysiological activity. Capitalizing on previous works that factor out acoustic information, we could concentrate lexical contribution language processing by testing competing statistical models. We exploited electroencephalographic recordings compared different surprisal models selectively involving part of speech, or structures various combinations. Electroencephalographic responses were recorded 32 participants during listening affirmative active declarative sentences. activation corresponding basic structures, such as noun phrases vs. verb phrases. Lexical activates frequency bands, partially time windows, networks. Moreover, based speech inventory only do not explain well data, while those including do. By disentangling acoustic, demonstrated differential sensitivity information. These results confirm extend measures obtained with intracranial recordings, supporting our hypothesis crucial neural processing. This study provides a detailed understanding how processes highlighting importance shaping comprehension.

Язык: Английский

Процитировано

0
Verbal working memory and syntactic comprehension segregate into the dorsal and ventral streams, respectively DOI Creative Commons
William Matchin,

Zeinab Khoshhal Mollasaraei,

Leonardo Bonilha

и другие.

Brain Communications, Год журнала: 2024, Номер 6(6)

Опубликована: Янв. 1, 2024

Abstract Syntactic processing and verbal working memory are both essential components to sentence comprehension. Nonetheless, the separability of these systems in brain remains unclear. To address this issue, we performed causal-inference analyses based on lesion connectome network mapping using MRI behavioural testing two groups individuals with chronic post-stroke aphasia. We employed a rhyme judgement task heavy load without articulatory confounds, controlling for overall ability match auditory words pictures perform metalinguistic judgement, isolating effect (103 individuals). assessed non-canonical comprehension, syntactic by incorporating residual performance as covariate (78 Voxel-based structural connectome-based symptom total volume were performed, permutation correct multiple comparisons (4000 permutations). observed that effects localized dorsal stream damage: posterior temporal-parietal lesions frontal-parietal white matter disconnections. These differentiated from comprehension deficits, which primarily associated ventral temporal lobe disconnections, particularly when measure covariate. Our results support conclusion distinct networks, largely loading onto streams, respectively.

Язык: Английский

Процитировано

0