Inhibitory control of speech production in the human premotor frontal cortex

Nature Human Behaviour, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

Язык: Английский

---

An active inference account of stuttering behavior

Frontiers in Human Neuroscience, Год журнала: 2025, Номер 19

Опубликована: Апрель 3, 2025

This paper presents an interpretation of stuttering behavior, based on the principles active inference framework. Stuttering is a neurodevelopmental disorder characterized by speech disfluencies such as repetitions, prolongations, and blocks. The inference, theory predictive processing sentient can be used to conceptualize disruption in perception-action cycling underlying production. proposed here posits that arises from aberrant sensory precision prediction error dynamics, inhibiting syllable initiation. Relevant this theory, two hypothesized mechanisms are proposed: (1) mistiming (2) excessive attentional focus. Both highlight role neural oscillations, error, hierarchical integration framework also explains contextual variability behaviors, including adaptation effects fluency-inducing conditions. Reframing synaptopathy integrates neurobiological, psychological, behavioral dimensions, suggesting disruptions precision-weighting mediated neuromodulatory systems. perspective provides unified account sets stage for innovative research therapeutic approaches.

Язык: Английский

---

The role of anticipation and neuroticism in developmental stuttering

Frontiers in Psychology, Год журнала: 2025, Номер 16

Опубликована: Май 21, 2025

People Who Stutter (PWS) are often characterized by the presence of cognitive-emotional issues, resulting in conditions such as social phobia and avoidance behaviors. Emotions have been demonstrated to a role modulating speech-motor systems. Thus, PWS, emotion cognition (i.e., higher levels trait-stable-neuroticism-and contextual-anticipation-anxiety) could negatively influence networks, an increased number dysfluencies. To test this hypothesis, we recruited 13 PWS who were matched Fluent Speakers (FS). Participants all Italian speakers completed NEO-PI-3 scale assess neuroticism, ASI-3 for anxiety sensitivity. Successively, participants considered 55 words (repeated two times) sentences, task which they had evaluate their anticipation stuttering before reading them aloud. Anticipation scores, times, frequency evaluated used analyses. Findings suggest that mainly concern than fluent speakers. Moreover, tendency toward neuroticism is evident. Linear regressions times (positively related stuttering) may be explained scores and, secondarily, levels. Stuttering was also positively recorded frequencies useful indexes predicting dysfluencies speech behavior, PWS. Surely, long-life adaptive/maladaptive compensation attempts. In every case, clinical context, suggests importance fully evaluating behavioral/emotional aspects stuttering, obtain more complete picture patients' needs "tailored"/multidisciplinary interventions.

Язык: Английский

---

Influences of speaking task demands on sensorimotor oscillations in adults who stutter: Implications for speech motor control

Clinical Neurophysiology, Год журнала: 2024, Номер 169, С. 76 - 88

Опубликована: Ноя. 10, 2024

Язык: Английский

---

Eliciting Stuttering in School-Age and Adolescent Stutterers in Experimental Settings

Journal of Speech Language and Hearing Research, Год журнала: 2023, Номер 66(5), С. 1631 - 1638

Опубликована: Апрель 14, 2023

Most neural and physiological research on stuttering focuses the fluent speech of speakers who stutter due to difficulty associated with eliciting reliably in laboratory. We previously introduced an approach elicit stuttered laboratory adults stutter. The purpose this study was determine whether that elicits school-age children teenagers (CWS/TWS).

Язык: Английский

---

Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective?

Frontiers in Human Neuroscience, Год журнала: 2024, Номер 18

Опубликована: Июнь 19, 2024

Developmental stuttering (DS) is a neurodevelopmental speech-motor disorder characterized by symptoms such as blocks, repetitions, and prolongations. Persistent DS often has significant negative impact on quality of life, interventions for it have limited efficacy. Herein, we briefly review existing research the neurophysiological underpinnings -specifically, brain metabolic default mode/social-cognitive networks (DMN/SCN) anomalies- arguing that psychedelic compounds might be considered investigated (e.g., in randomized clinical trials) treatment DS. The neural background likely to heterogeneous, some contribution from genetically determinants deficiencies basal ganglia cortical regions are thought play role appearance symptoms, which possibly results cascade events contributing impairments execution. In persistent DS, difficulties speech linked series associated aspects social anxiety avoidance. this context, SCN DMN (also influencing fronto-parietal, somato-motor, attentional networks) may worsening dysfluencies. Interestingly, metabolism SCN/DMN connectivity can modified psychedelics, been shown improve evidence psychiatric conditions depression, post-traumatic stress disorder, etc.) with psychological constructs rumination anxiety, also tend present To date, while there no controlled trials effects psychedelics anecdotal suggests these agents beneficial its characteristics. We suggest warrant investigation

Язык: Английский

---

Reduced resting-state periodic beta power in adults who stutter is related to sensorimotor control of speech execution

Cortex, Год журнала: 2024, Номер 181, С. 74 - 92

Опубликована: Окт. 24, 2024

Язык: Английский

---