Frontiers in Medicine,
Год журнала:
2023,
Номер
10
Опубликована: Июль 18, 2023
Purpose
To
explore
the
etiology
and
choroidal
thickness
(ChT)
pattern
in
children
with
early-onset
high
myopia
(eoHM).
Methods
Sixty
eoHM
20
healthy
controls
were
enrolled
this
study
between
January
2019
December
2021.
All
underwent
comprehensive
ophthalmologic
examinations
including
swept-source
optical
coherence
tomography.
ChT
was
measured
subfoveal
region
at
1000
μm
2,500
nasal,
temporal,
superior,
inferior
to
fovea.
Results
Overall,
120
eyes
of
60
examined
(mean
spherical
equivalent,
−8.88
±
3.05
D;
mean
axial
length,
26.07
1.59
mm).
Simple
(SHM),
familial
exudative
vitreoretinopathy
(FEVR),
Stickler
syndrome
(STL)
most
frequent
etiologies
included
further
analysis.
Adjusted
effect
SE,
multivariate
regression
analysis
showed
that
SHM
had
thinnest
N
2500
I
among
subgroups
(
p
=
0.039,
0.013).
FEVR
group
thinner
T
0.023),
while
STL
patients
exhibited
thin
all
locations.
Conclusion
This
revealed
SHM,
etiology,
a
distinctive
ChT.
Asymmetric
nasal
thinning
is
biomarker
for
asymmetric
temporal
might
serve
as
FEVR,
symmetric
diffuse
more
common
STL.
These
patterns
may
provide
convenient,
fast,
noninvasive
strategy
differentiate
potential
eoHM.
Current Eye Research,
Год журнала:
2024,
Номер
49(4), С. 437 - 445
Опубликована: Янв. 7, 2024
We
employed
automated
analysis
of
scanning
laser
ophthalmoscopy
(SLO)
to
determine
if
mechanical
strains
imposed
on
disc,
and
retinal
choroidal
vessels
during
horizontal
duction
in
children
differ
from
those
adults.
