Research on the predictive performance of using ROC curve to evaluate axial length for myopia in children and adolescents DOI Creative Commons

Cui Mingming,

Zhu Zhongxin,

Yuting Gao

и другие.

BMC Ophthalmology, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 10, 2025

Assessing myopia risk can help clinicians intervene as early possible. There is still a lack of reference values for predicting based on the axial length (AL) children. The study aims to explore relationship between AL and myopia, predict thresholds in children different age sex groups. Visual acuity examination, refractive screening ocular axis examination 2388 aged 7-18 (4776 eyes) from 8 schools certain area Beijing were used data source, we evaluated predictive ability using Receiver Operating Characteristic (ROC) curves, constructed Logistic Regression analyze value threshold rate among adolescents was 51.47%. SE significantly correlated by Spearman correlation coefficient(P < 0.01). Predicting their has good value(AUC = 0.73). Children with ≥ 23.92 mm have higher than those (χ²=661.14, P difference groups statistically significant, shows an increasing trend age. Among them, 7-12 23.67 mm, while that 13-15 16-18 24.42 mm. 4.41-fold (OR 4.41, 95% CI 3.88-5.01). significant male group AL(24.27 mm) females (23.71 mm), 5.58-fold 5.58, 4.93-6.33). strong school Age-specific sex-specific might provide useful indicator, aid identifying monitoring individuals at utility population-based adolescents.

Язык: Английский

IMI 2023 Digest DOI Creative Commons
Padmaja Sankaridurg, David A. Berntsen, Mark A. Bullimore

и другие.

Investigative Ophthalmology & Visual Science, Год журнала: 2023, Номер 64(6), С. 7 - 7

Опубликована: Май 1, 2023

Myopia is a dynamic and rapidly moving field, with ongoing research providing better understanding of the etiology leading to novel myopia control strategies. In 2019, International Institute (IMI) assembled published series white papers across relevant topics updated evidence digest in 2021. Here, we summarize findings key from previous 2 years. Studies animal models have continued explore how wavelength intensity light influence eye growth examined new pharmacologic agents scleral cross-linking as potential strategies for slowing myopia. children, term premyopia gaining interest increased attention early implementation control. Most studies use IMI definitions ≤-0.5 diopters (D) ≤-6.0 D high myopia, although categorization structural consequences remain an issue. Clinical trials demonstrated that newer spectacle lens designs incorporating multiple segments, lenslets, or diffusion optics exhibit good efficacy. considerations factors influencing efficacy soft multifocal contact lenses orthokeratology are discussed. Topical atropine remains only widely accessible treatment. Rebound observed higher concentration not evident lower concentrations optical interventions. Overall, treatments show little adverse effect on visual function appear generally safe, longer wear times combination therapies maximizing outcomes. An emerging category light-based children requires comprehensive safety data enable risk versus benefit analysis. Given success strategies, ethics including arm clinical heavily debated. recommendations trial protocols

Язык: Английский

Процитировано

57
Myopia Control: Are We Ready for an Evidence Based Approach? DOI Creative Commons
Leila Sara Eppenberger, Andrzej Grzybowski, Leopold Schmetterer

и другие.

Ophthalmology and Therapy, Год журнала: 2024, Номер 13(6), С. 1453 - 1477

Опубликована: Май 7, 2024

Myopia and its vision-threatening complications present a significant public health problem. This review aims to provide an updated overview of the multitude known emerging interventions control myopia, including their potential effect, safety, costs. A systematic literature search three databases was conducted. Interventions were grouped into four categories: environmental/behavioral (outdoor time, near work), pharmacological (e.g., atropine), optical (spectacles contact lenses), novel approaches such as red-light (RLRL) therapies. Review articles original on randomized controlled trials (RCT) selected. From initial 3224 retrieved records, 18 reviews 41 reporting results from RCTs included. While there is more evidence supporting efficacy low-dose atropine certain myopia-controlling lenses in slowing myopia progression, about newer interventions, spectacle defocus incorporated multiple segments highly aspheric lenslets) limited. Behavioral i.e., increased outdoor seem effective for preventing onset if implemented successfully schools homes. environmental spectacles are regarded generally safe, lenses, RLRL may be associated with adverse effects. All except behavioral change, tied moderate high expenditures. Our suggests that recommended prescribed basis accessibility clinical practice patterns, which vary widely around world. Clinical indicate short- medium-term reducing progression various but none have demonstrated long-term effectiveness adulthood. There unmet need unified consensus strategies balance risk these methods personalized management.

Язык: Английский

Процитировано

11
Myopia Control Effect of Repeated Low-Level Red-Light Therapy Combined with Orthokeratology DOI
Ruilin Xiong, Wei Wang, Xianghua Tang

и другие.

Ophthalmology, Год журнала: 2024, Номер 131(11), С. 1304 - 1313

Опубликована: Май 18, 2024

Язык: Английский

Процитировано

8
European trends in attitudes and strategies for myopia management in clinical practice DOI Creative Commons
Clara Martínez-Pérez, Jacinto Santodomingo‐Rubido, César Villa Collar

и другие.

Contact Lens and Anterior Eye, Год журнала: 2025, Номер unknown, С. 102390 - 102390

Опубликована: Март 1, 2025

BackgroundSurveys conducted between 2015 and 2022 showed growing concern among European eye care practitioners about myopia management, though adoption of effective strategies varied. This study updates findings from 2024, analysing trends in attitudes for management across Europe to 2024.MethodsA cross-sectional online survey targeting was distributed multiple languages through professional bodies. It assessed awareness prevalence, perceived efficacy different control strategies, reasons non-adoption.ResultsBetween a total 3,179 responses were collected practitioners, representing data four years. Concern pediatric varied significantly 2024 (P < 0.001), with Portugal reporting the highest (9.4 ± 1.0) Sweden lowest (5.9 2.2). Orthokeratology combined low-dose atropine as most approach (60.8 29.6), followed by solo orthokeratology (60.1 25.0) approved soft contact lenses (55.9 23.4). Single-vision (15.9 22.9) undercorrection (7.1 16.6) rated least effective. Since 2015, single-vision lens prescribing has declined, while spectacles lenses, combination therapies have increased. The major preventing prescription methods cost (29.6 %), treatment availability (11.4 %) inadequate information/knowledge (9.3 %). Factors such patient age, refractive error, parental influenced choices, factors being less influential Russia compared other countries (all p ≤ 0.001). All reported that adopting measures progression thought improve loyalty (much more/more: 57.7 job satisfaction 73.3 but it not increase practice revenue 43.3 %).ConclusionsEuropean are increasingly evidence-based relatively similar practices. Offering enhanced satisfaction. However, barriers limited still impede broader adoption.

Язык: Английский

Процитировано

1
Eyecare practitioner perspectives and attitudes towards myopia and myopia management in the UK DOI Creative Commons
Sophie Coverdale, Lindsay Rountree, Kathryn Webber

и другие.

BMJ Open Ophthalmology, Год журнала: 2024, Номер 9(1), С. e001527 - e001527

Опубликована: Янв. 1, 2024

Objective Many children with progressive myopia are still prescribed single-vision correction. An investigation into UK eyecare practitioners’ (ECPs) perceptions of management was carried out to ascertain factors which may be limiting its implementation and uptake within clinical practice. Methods analysis Online focus groups were held ECPs. Participants encouraged discuss their knowledge the available options, perception how is being delivered in any barriers ECPs' prescribing these options The discussions transcribed analysed thematically. Results Focus 41 ECPs from primary secondary eyecare. felt that provision variable. Most believe they have sufficient knowledge, but a lack confidence decision-making practical experience. Less experienced sought more definitive guidance support decision-making. desired clarity on duty care obligations concerned over possible future litigation if had not offered, or referred for, when indicated. greatest barrier appears financial—treatment expensive uncomfortable communicating this parents. indicative systemic problems eyecare, such as commercial pressures, inadequate National Health Service funding poor public awareness paediatric Conclusion Myopia implemented consistently across UK. To improve accessibility, changes required at multiple levels, individual through wider stakeholders provision.

Язык: Английский

Процитировано

6
Myopia information on TikTok: analysis factors that impact video quality and audience engagement DOI Creative Commons
Shuai Ming, Jie Han, Xi Yao

и другие.

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Апрель 29, 2024

TikTok is emerging as a vital platform for health information dissemination. Despite myopia being global public issue, the high-quality shared by educators often fails to go viral. It imperative analyze factors influencing video quality and popularity, especially from diverse perspectives of researchers, educators, audiences.

Язык: Английский

Процитировано

6
A new look at the myopia control efficacy of orthokeratology DOI
Jacinto Santodomingo‐Rubido,

Sin-Wan Cheung,

César Villa-Collar

и другие.

Contact Lens and Anterior Eye, Год журнала: 2024, Номер 47(5), С. 102251 - 102251

Опубликована: Июнь 21, 2024

Язык: Английский

Процитировано

6
Time Spent Outdoors Partly Accounts for the Effect of Education on Myopia DOI Creative Commons
Rosie Clark, Sander C. M. Kneepkens, Denis Plotnikov

и другие.

Investigative Ophthalmology & Visual Science, Год журнала: 2023, Номер 64(14), С. 38 - 38

Опубликована: Ноя. 27, 2023

Purpose: The purpose of this study was to investigate if education contributes the risk myopia because educational activities typically occur indoors or other factors, such as prolonged near viewing. Methods: This a two-sample Mendelian randomization study. Participants were from UK Biobank, Avon Longitudinal Study Parents and Children, Generation R. Genetic variants associated with years spent in time outdoors used instrumental variables. main outcome measures were: (1) spherical equivalent refractive error attained by adulthood, (2) an early age-of-onset spectacle wear (EAOSW), defined 15 below. Results: Time found have small genetic component (heritability 9.8%) that tracked childhood adulthood. A polygenic score for children's outdoors; inversely outdoors. Accounting relationship between multivariable analysis reduced size causal effect more on −0.17 diopters (D) per additional year formal (95% confidence interval [CI] = −0.32 −0.01) compared estimate univariable −0.27 D CI −0.41 −0.13). Comparable results obtained EAOSW. Conclusions: effects estimated 40%. These suggest about half may be mediated children not being during schooling.

Язык: Английский

Процитировано

10
Short-term choroidal changes as early indicators for future myopic shift in primary school children: results of a 2-year cohort study DOI
Hao Wu, M. Liu, Yuanyuan Wang

и другие.

British Journal of Ophthalmology, Год журнала: 2024, Номер unknown, С. bjo - 325871

Опубликована: Сен. 3, 2024

Background To assess predictive value of short-term choroidal changes for future myopic shift in children. Methods 577 eyes 289 primary school children were prospectively followed 2 years. Cycloplegic refractions at baseline, 1 year and years, measurements by optical coherence tomography baseline 3 months, used analyses. Myopic was defined as refraction change least −0.50 dioptre/year, years compared with baseline. Results 228 participants (455 eyes) completed 2-year follow-up. Approximately 37.6% 311 initially non-myopic 73.6% 144 developed a shift. Notably, months greater reductions found shift, than those without shift—in thickness (ChT), luminal area (LA), stromal (SA) total (TCA), but no significant differences any parameters observed between eyes, Multivariable analyses showed that each percentage increase ChT, LA, SA TCA associated reduced odds (all p<0.001). Similar associations smaller effects eyes. Adding 3-month parameter to basic model including age, gender, parental myopia significantly improved the performance (area under receiver operating characteristic curves increasing from 0.650 approximately 0.800, all p<0.05), not Conclusion Short-term could act early indicators

Язык: Английский

Процитировано

4
Effectiveness of a Spectacle Lens with a Specific Asymmetric Myopic Peripheral Defocus: 12-Month Results in a Spanish Population DOI Creative Commons
Miguel Ángel Sánchez‐Tena, José Miguel Cleva, César Villa Collar

и другие.

Children, Год журнала: 2024, Номер 11(2), С. 177 - 177

Опубликована: Фев. 1, 2024

Different designs of ophthalmic lenses have been studied to control the progression myopia in children. This study aims evaluate short-term efficacy a new design lens with asymmetric myopic peripheral defocus (MPDL) on children compared group wearing single-vision (SVL). Children aged 5 12 up -0.50 D, astigmatism and anisometropia under 1.50 corrected visual acuity over 20/20 were randomized either or The was evaluated by measuring axial length (AL) growth (IOL Master; Zeiss) period one year. Ninety-two subjects recruited. Forty-six randomly assigned group, 46 group. In total, 83 completed clinical trial, mean age 10.81 [9.53-11.92] years, among which 59.04% female. After year treatment, there less AL elongation (0.16 ± 0.16 mm vs. 0.24 mm, p = 0.034). MPDL significantly reduced absolute 39% (p 0.014) relative 37.3% 0.012) after months comparison Spanish population.

Язык: Английский

Процитировано

3