Letter: Comment on; “Left Ventricular Global Function Index and Major Adverse Cardiovascular Events Linked to Systemic Inflammation in Acute Coronary Syndrome”

Angiology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 24, 2025

Язык: Английский

Left Ventricular Global Function Index: A Potential Predictor of Mortality and Major Adverse Cardiovascular Events in NSTEMI Patients

Medicina, Год журнала: 2025, Номер 61(3), С. 487 - 487

Опубликована: Март 11, 2025

Background and Objectives: The prognostic value of Left Ventricular Global Function Index (LVGFI) in chronic cardiovascular diseases is well-documented; however, limited evidence exists for its utility non-ST elevation myocardial infarction (NSTEMI). This study aims to evaluate LVGFI as a predictor three-year mortality major adverse events (MACE) NSTEMI patients. Materials Methods: retrospective cohort included 432 patients divided into tertiles based on values: T1 (low), T2 (intermediate), T3 (high). values were derived from echocardiographic imaging. Kaplan–Meier survival analysis was used assess outcomes, the Cox proportional hazards models, adjusted demographics clinical covariates, determined association between outcomes. Results: average age sex distribution similar across with no significant differences risk factors or most laboratory parameters. However, noted body surface area (higher T3), platelet counts T1), triglyceride levels (lower T3). ROC identified an optimal cut-off 23.22 predicting mortality, sensitivity 72% specificity 75% (AUC: 0.81; 95% CI: 0.74–0.87, p < 0.001). Patients exhibited rate 25%, compared 2.1% T3. After adjustment, hazard ratio (HR) significantly higher (HR 11.86; 3.60–39.10) Similarly, MACE rates highest (27.1%) lowest (7.6%). Conclusions: independent

Язык: Английский

Response to the Letter to the Editor: “LVGFI and MACE Linked to Systemic Inflammation in Acute Coronary Syndrome”

Angiology, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

Язык: Английский