3D Bioprinting: Shaping the Future of Periodontal Tissue Regeneration and Disease Management DOI Open Access

Jemish Acharya,

Santosh Kumar, Gaurav Girdhar

и другие.

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

The periodontium is one of the most complex tissues in body, consisting a hierarchical blend soft and hard tissues. Its architecture makes treating regenerating disease-damaged periodontal persistent challenge biomedicine. Three-dimensional (3D) bioprinting represents transformative approach to tissue engineering, offering promising advancements disease. This innovative technology enables precise fabrication complex, patient-specific structures, facilitating repair restoration damaged tissues, including gingiva, bone, ligament (PDL). By utilizing biocompatible materials such as living cells, hydrogels, growth factors, 3D has potential create functional, biologically integrated constructs that can mimic natural However, translating these into clinical applications remains challenge. Emerging technologies like have been developed address some limitations traditional engineering methods. review explores current state technology, its application disease treatment, challenges associated with scaling up this for use. Additionally, it discusses future implications personalized medicine, new frontier improving patient outcomes oral health. Integrating regenerative therapies could revolutionize practices, more effective, tailored, sustainable solutions

Язык: Английский

Bibliometric analysis of additive manufacturing in cranial and craniofacial implant research DOI
Bengi Yılmaz, Simel Ayyıldız

Journal of Cranio-Maxillofacial Surgery, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

The rise of 3D bioprinting: from organs to personalized medicine DOI Creative Commons
Kirolos Eskandar

Patient-Oriented Medicine and Pharmacy, Год журнала: 2025, Номер unknown

Опубликована: Март 7, 2025

Bioprinting has emerged as a groundbreaking technology in the realms of organ transplantation and regenerative medicine, addressing critical challenges such shortages tissue repair. This review explores technological advancements innovations bioprinting, highlighting state-of-the-art techniques, bioinks, applications engineering. Key milestones printing functional tissues, including vascularized transplantable prototypes, are discussed alongside role bioprinting personalized where patient-oriented models revolutionizing drug testing therapeutic strategies. Furthermore, this article examines ethical considerations associated with offering insights into its future potential to transform global healthcare.

Язык: Английский

Процитировано

0

The Next Frontier in Aesthetics: 3D Bioprinting for Personalized Skin Regeneration DOI Creative Commons
Diala Haykal

Journal of Cosmetic Dermatology, Год журнала: 2025, Номер 24(4)

Опубликована: Март 26, 2025

Cosmetic dermatology is entering a new frontier with the advent of 3D bioprinting, technology poised to revolutionize way we approach skin regeneration, aesthetic enhancement, and personalized dermatologic interventions [1]. While initially developed for reconstructive applications, bioprinted may soon redefine anti-aging treatments, scar revision, even volumetric facial rejuvenation. The ability print customized grafts using patient's own cells presents an unprecedented opportunity natural, long-lasting results that go beyond current injectables or energy-based devices [2]. Unlike synthetic fillers collagen stimulators, bioengineered has potential integrate seamlessly native tissue, not just restoring lost elasticity improving texture but also offering truly volume restoration wrinkle repair. development bioinks composed extracellular matrix components, fibroblasts, keratinocytes made it possible recreate full-thickness layers, closely mimicking natural architecture [3]. This breakthrough paves regenerative therapies tailored unique biology, major leap from primarily focus on temporary improvements. Recent studies have already explored possibility bioprinting constructs replicate biomechanical pigmentation properties, which could provide highly solutions ethnic tones, hyperpigmentation disorders, remodeling [1, 4]. be game changer in treating post-inflammatory hyperpigmentation, vitiligo, burn scars, where uniform repigmentation remains significant challenge. What if, instead depigmentation camouflage techniques, bioprint new, pigment-matched skin? implications are enormous. Beyond direct holds promise testing cosmetic formulations, optimizing post-procedure recovery, hosting patient-specific microbiomes. Traditional vitro models lack complexity real skin, limiting predict how skincare products, fillers, treatments will interact human tissue. Bioprinted bridge this gap, serving as functional platforms eliminate need animal more accurate insights into product safety efficacy [5]. With AI-driven modeling, future regeneration becomes precise. AI-assisted tissue engineering optimize scaffold design, ensuring enhance synthesis, modulate inflammation, restore dermal [6]. manage atrophic keloids, aging-related loss, moving us away toward long-term regeneration. possibilities vast, yet surprisingly underexplored research. Despite its promise, raises critical questions about regulatory pathways, accessibility, ethical considerations. Will these classified medical luxury enhancements? Could customized, youthful fuel unrealistic expectations medicine? designer aesthetics shaping beauty trends through consultations, far patients requesting modifications idealized standards rather than restoration? These dermatologists, researchers, policymakers must address continues advance. Another challenge cost accessibility. widely available, expensive largely experimental. become niche service reserved high-end clinics, advancements biofabrication make scalable accessible broader population? considerations taken account transitions lab clinical practice. field continually evolving, now time start conversation reshape treatment paradigms. create personalized, exciting challenge, one lead fundamental shift medicine. As progresses, interdisciplinary collaboration crucial bridging gap between medicine, dermatology, biotechnology. medicine reversing time, bioengineering evolve it. However, further research essential fully understand efficacy, safety, applications. author declares no conflicts interest. data support findings study available references' part.

Язык: Английский

Процитировано

0

Advances in bioink-based 3D printed scaffolds: optimizing biocompatibility and mechanical properties for bone regeneration DOI
Pawan Kumar, Jitender Sharma, Ravinder Kumar

и другие.

Biomaterials Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

The development of bioink-based 3D-printed scaffolds has revolutionized bone tissue engineering (BTE) by enabling patient-specific and biomimetic constructs for regeneration.

Язык: Английский

Процитировано

0

3D Bioprinting: Shaping the Future of Periodontal Tissue Regeneration and Disease Management DOI Open Access

Jemish Acharya,

Santosh Kumar, Gaurav Girdhar

и другие.

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

The periodontium is one of the most complex tissues in body, consisting a hierarchical blend soft and hard tissues. Its architecture makes treating regenerating disease-damaged periodontal persistent challenge biomedicine. Three-dimensional (3D) bioprinting represents transformative approach to tissue engineering, offering promising advancements disease. This innovative technology enables precise fabrication complex, patient-specific structures, facilitating repair restoration damaged tissues, including gingiva, bone, ligament (PDL). By utilizing biocompatible materials such as living cells, hydrogels, growth factors, 3D has potential create functional, biologically integrated constructs that can mimic natural However, translating these into clinical applications remains challenge. Emerging technologies like have been developed address some limitations traditional engineering methods. review explores current state technology, its application disease treatment, challenges associated with scaling up this for use. Additionally, it discusses future implications personalized medicine, new frontier improving patient outcomes oral health. Integrating regenerative therapies could revolutionize practices, more effective, tailored, sustainable solutions

Язык: Английский

Процитировано

0