Overview of mucosal immunity and respiratory infections in children: a focus on Africa

Current Opinion in Pediatrics, Год журнала: 2025, Номер unknown

Опубликована: Фев. 4, 2025

Given the substantial burden of respiratory tract infections (RTIs) on global paediatric health, enhancing our understanding mucosal immunity can help us advance biomarkers for diagnosis, prognosis and possible interventions in order to improve health outcomes. This review highlights critical role RTIs recent advances interventions, which offer promising strategies The significant growing interest advanced immune system protective against RTIs. Studies show that sub-Saharan Africa is disproportionately affected by with poverty-associated factors such as human immunodeficiency virus (HIV) malnutrition risk factors. Emerging evidence important microbiome innate adaptive responses has not only overall but also created opportunities RTI care through translation knowledge from these studies into diagnostics, therapeutics, vaccines.

Язык: Английский

Salivary polyreactive antibodies, airway bacteria, and recurrent respiratory infection severity

European Respiratory Journal, Год журнала: 2024, Номер 64(4), С. 2401526 - 2401526

Опубликована: Окт. 1, 2024

Язык: Английский