Follistatin, A Novel Therapeutic Target for Chronic Pain
Neuroscience Bulletin,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 2, 2025
Язык: Английский
Environmental enrichment for neuropathic pain via modulation of neuroinflammation
Frontiers in Molecular Neuroscience,
Год журнала:
2025,
Номер
18
Опубликована: Март 21, 2025
Neuropathic
pain
causes
tremendous
biological
and
psychological
suffering
to
patients
worldwide.
Environmental
enrichment
(EE)
is
a
promising
non-pharmacological
strategy
with
high
cost-effectiveness
reduce
neuropathic
support
rehabilitation
therapy.
Three
researchers
reviewed
previous
studies
determine
the
efficacy
of
EE
for
research
how
improves
through
neuroinflammation.
For
this
review,
Embase,
PubMed,
Cochran
were
searched.
authors
did
study
selection
data
extraction.
Out
74
papers,
7
met
inclusion
criteria.
In
chronic
constriction
injury
rats
acute
or
detrimental
stimulation,
change
behavior
was
influenced
by
environmental
settings
like
start
time,
cage
size.
Besides,
physical
has
larger
effect
than
socially
in
inflammatory
pain.
These
articles
suggest
employing
various
regulate
release
pain-causing
substances
changes
ion
channels
peripheral
central
nerves
improve
depression
anxiety
conditions.
The
existing
proof
provides
important
knowledge
upcoming
preclinical
investigations
practical
use
clinical
treatment.
This
analysis
aids
advancement
improved
approaches
managing
pain,
focus
on
internal
mechanisms
controlling
Язык: Английский
Knowledge Mapping and Emerging Trends in Cognitive Impairment Associated with Chronic Pain: A 2000-2024 Bibliometric Study
Brain Research Bulletin,
Год журнала:
2024,
Номер
unknown, С. 111175 - 111175
Опубликована: Дек. 1, 2024
Chronic
pain
is
commonly
recognized
as
a
distressing
symptom
or
standalone
disease,
with
over
half
of
those
affected
experiencing
cognitive
impairment,
which
significantly
impacts
their
quality
life.
Despite
recent
surge
in
literature
on
impairment
associated
chronic
pain,
comprehensive
bibliometric
analysis
this
field
has
yet
to
be
conducted.
In
study,
we
performed
topic.
We
retrieved
English-language
publications
and
from
2000
2024
using
the
Web
Science
Core
Collection
database.
These
were
visually
analyzed
tools
such
VOSviewer,
CiteSpace,
R
package
"bibliometrix."
identified
1,656
72
countries/regions
across
722
journals
topic
impairment.
Publication
numbers
showed
steady
increase,
peaking
2022.
The
United
States
led
contributions,
Harvard
Medical
School
emerging
most
prominent
institution
involved.
journal
Pain
was
prolific
frequently
co-cited
area.
Among
authors,
Stefan
Duschek
productive,
while
Frederick
Wolfe
co-cited.
Key
research
areas
include
investigating
bidirectional
long-term
effects
between
exploring
mechanisms
underlying
changes
pain.
conclusion,
study
highlights
global
related
Emerging
hotspots
future
trends
point
towards
brain
imaging
neuronal
circuit-mediated
processes.
Язык: Английский