
Frontiers in Psychiatry, Год журнала: 2025, Номер 15
Опубликована: Янв. 31, 2025
The Framingham Steatosis Index (FSI) serves as a diagnostic metric for fatty liver. While research has established link between depression and liver, the association with remains undocumented. aim of this study is to explore potential correlation FSI depression, addressing void. Our data originates from National Health Nutrition Examination Survey (NHANES) database. We employed PHQ-9 questionnaire evaluation depressive symptoms. investigated using weighted multiple logistic regression model stratified analysis. Non-linear associations were explored fitted smooth curves. A recursive method was identify inflection points. Subgroup analyses conducted examine differences in within subgroups. encompassed total 19,697 participants. Multivariate analysis, adjusted confounding factors, demonstrated significant positive OR 1.14 (95% CI: 1.10, 1.18). Stratified analysis indicated that exists among all groups except those BMI below 30. non-linear relationship further confirmed by restricted cubic splines which revealed an point at value 29.72. Below threshold, there no correlation, while above it, observed. statistically interactions educational attainment groups. study's discovery curvilinear depression. Factors such inflammation, hormonal levels, metabolic disruptions could be underlying mechanisms driving relationship. This finding offers valuable insights inform development comprehensive intervention strategies managing clinical settings.
Язык: Английский