Correlations among lymphocyte count, white matter hyperintensity and brain atrophy in patients with ischemic stroke DOI Creative Commons
Chenchen Liu, Shi Dai,

Xiaoqiong Ni

и другие.

Frontiers in Aging Neuroscience, Год журнала: 2025, Номер 16

Опубликована: Янв. 8, 2025

White matter hyperintensity (WMH) and brain atrophy, as imaging marker of cerebral small-vessel diseases (CSVD), have a high prevalence strong prognostic value in stroke. We aimed to explore the association between lymphocyte count, maker inflammation, WMH atrophy patients with acute ischemic stroke (AIS). A total 727 AIS count magnetic resonance data were enrolled. Participants divided into four groups according quartiles baseline counts. is frequently periventricular (PVH) deep white (DWMH). was defined Fazekas scale score ≥ 3; PVH ≥2; DWMH ≥2. Brain global cortical 1. Multivariable logistic regression models used assess atrophy. Among AIS, 517 (71.1%), 442 (60.8%), 459 (63.1%), 583 (80.2%) had WMH, PVH, respectively. After adjustment for potential covariates, highest counts significantly associated lower risk (adjusted odds ratio [aOR] 0.57, 95% confidence intervals [CI] 0.32-0.99), (aOR 0.52, CI 0.31-0.87), 0.53 0.32-0.90) well 0.46, 0.23-0.92) compared lowest counts, Furthermore, notable inverse observed continuous DWMH, Additionally, we found that significant only individuals mild In there an independent both

Язык: Английский

Correlations among lymphocyte count, white matter hyperintensity and brain atrophy in patients with ischemic stroke DOI Creative Commons
Chenchen Liu, Shi Dai,

Xiaoqiong Ni

и другие.

Frontiers in Aging Neuroscience, Год журнала: 2025, Номер 16

Опубликована: Янв. 8, 2025

White matter hyperintensity (WMH) and brain atrophy, as imaging marker of cerebral small-vessel diseases (CSVD), have a high prevalence strong prognostic value in stroke. We aimed to explore the association between lymphocyte count, maker inflammation, WMH atrophy patients with acute ischemic stroke (AIS). A total 727 AIS count magnetic resonance data were enrolled. Participants divided into four groups according quartiles baseline counts. is frequently periventricular (PVH) deep white (DWMH). was defined Fazekas scale score ≥ 3; PVH ≥2; DWMH ≥2. Brain global cortical 1. Multivariable logistic regression models used assess atrophy. Among AIS, 517 (71.1%), 442 (60.8%), 459 (63.1%), 583 (80.2%) had WMH, PVH, respectively. After adjustment for potential covariates, highest counts significantly associated lower risk (adjusted odds ratio [aOR] 0.57, 95% confidence intervals [CI] 0.32-0.99), (aOR 0.52, CI 0.31-0.87), 0.53 0.32-0.90) well 0.46, 0.23-0.92) compared lowest counts, Furthermore, notable inverse observed continuous DWMH, Additionally, we found that significant only individuals mild In there an independent both

Язык: Английский

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