Prior
research
has
demonstrated
that
people
with
cataracts
are
more
likely
to
experience
anxiety
and
depression
co-occurring
when
the
condition
advances
a
degree
impairs
vision
beyond
its
physiological
effects.
According
network
theory,
there
is
connection
between
interplay
of
genesis
comorbidity.
Using
viewpoint,
our
study
examined
properties
anxiety-depression
in
cataract
patients
pinpoint
central
bridge
symptoms
as
well
possible
intervention
targets
for
focused
successful
therapies.
A
total
1,254
were
enrolled
study.
The
Nine-item
Patient
Health
Questionnaire
(PHQ-9)
Seven-item
Generalized
Anxiety
Disorder
scale
(GAD-7)
used
measure
symptoms,
respectively.
R
4.3.3
software
was
utilized
model
building
descriptive
statistics.
Furthermore,
we
displayed
"Thoughts
death"
flow
network.
In
network,
A5
"Restlessness"-
D7
"Concentration
difficulties"
showed
strongest
edge.
A2
"Uncontrollable
worry"
D2
"Depressed
or
sad
mood"
could
be
identified
symptoms.
A7
"Afraid
something
will
happen"
edge
D9
death"-D6
"Feeling
worthlessness".
worry",
mood",
potential
prevention
patients.
this
emphasizes
how
important
it
prevent
suicide
patients,
symptom
worthlessness"
can
an
effective
target.
European Journal of Cardiovascular Nursing,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 2, 2025
Abstract
Aims
To
construct
a
symptom
network
of
chronic
heart
failure
patients
in
the
vulnerable
period
and
identify
core
symptoms
bridge
between
different
clusters.
Methods
results
A
convenience
sampling
method
was
used
to
select
402
with
within
3
months
after
discharge
from
cardiology
departments
two
tertiary-level
hospitals
Zhenjiang
City,
symptom-related
entries
Minnesota
living
questionnaire
(MLHFQ)
were
conduct
survey.
Symptom
networks
constructed
using
R
language.
The
structurally
stable,
correlation
stability
coefficient
0.595.
In
network,
‘depression’
(MLHFQ9),
‘dyspnoea
on
exertion’
(MLHFQ3),
‘worry’
(MLHFQ7)
are
symptoms.
‘Cognitive
problems’
(MLHFQ8),
‘sleep
difficulties’
(MLHFQ4),
‘fatigue’
(MLHFQ6)
connecting
emotional-cognitive
somatic
comparison
test,
there
no
significant
differences
genders
places
residence.
Conclusion
‘Depression’
‘increased
need
rest’
most
severe
symptoms,
respectively,
phase
failure,
‘cognitive
is
important
symptom.
Clinical
caregivers
can
build
precise
intervention
programme
based
focus
emotional
cognitive
clusters,
order
improve
efficacy
management
during
failure.
Elderly
individuals
living
alone
represent
a
vulnerable
group
with
limited
family
support,
making
them
more
susceptible
to
mental
health
issues
such
as
depression
and
anxiety.
This
study
aims
construct
network
model
of
anxiety
symptoms
among
older
adults
alone,
exploring
the
correlations
centrality
different
symptoms.
The
goal
is
identify
core
bridging
inform
clinical
interventions.
Using
data
from
2018
Chinese
Longitudinal
Healthy
Longevity
Survey
(CLHLS),
this
constructed
elderly
alone.
Depression
were
assessed
using
Center
for
Epidemiologic
Studies
Scale-10
(CESD-10)
Generalized
Anxiety
Disorder
Scale-7
(GAD-7),
respectively.
A
Gaussian
Graphical
Model
(GGM)
was
employed
build
symptom
network,
Fruchterman-Reingold
algorithm
used
visualization,
thickness
color
edges
representing
partial
between
To
minimize
spurious
correlations,
Least
Absolute
Shrinkage
Selection
Operator
(LASSO)
method
applied
regularization,
optimal
regularization
parameters
selected
Extended
Bayesian
Information
Criterion
(EBIC).
We
further
calculated
Expected
Influence
(EI)
Bridge
(Bridge
EI)
evaluate
importance
Non-parametric
bootstrap
methods
assess
stability
accuracy
network.
Network
analysis
revealed
that
GAD2
(Uncontrollable
worry)
GAD4
(Trouble
relaxing)
exhibited
highest
strength
(1.128
1.102,
respectively),
indicating
their
significant
direct
associations
other
roles
nodes
in
Other
highly
central
nodes,
GAD1
(Nervousness
or
anxiety)
GAD3
(Generalized
worry),
underscore
dominance
overall
Betweenness
results
highlighted
critical
bridge
facilitating
information
flow
symptoms,
while
CESD3
(Feeling
depressed)
demonstrated
role
across
modules.
Weighted
analyses
confirmed
relaxing).
Additionally,
showed
gender
differences
depression-anxiety
networks
study,
through
analysis,
uncovered
complex
relationships
identifying
These
findings
provide
essential
insights
targeted
Future
research
should
explore
intervention
strategies
these
improve
JMIR Aging,
Год журнала:
2025,
Номер
8, С. e64352 - e64352
Опубликована: Март 5, 2025
The
number
of
centenarians
worldwide
is
expected
to
increase
dramatically,
reaching
3.4
million
by
2050
and
>25
2100.
Despite
these
projections,
depression
remains
a
prevalent
yet
underdiagnosed
undertreated
condition
among
this
population
that
carries
significant
health
risks.
This
study
aimed
identify
achieve
consensus
on
the
most
representative
signs
symptoms
in
near-centenarians
(aged
≥95
years)
through
an
e-Delphi
with
international
interdisciplinary
panel
experts.
Ultimately,
outcomes
might
help
create
screening
instrument
specifically
designed
for
unique
population.
A
modified
was
carried
out
expert
depressive
centenarians.
28
experts
recruited.
Consensus
defined
as
70%
agreement
relevance
each
item.
Data
were
collected
web-based
questionnaire
over
3
rounds.
Experts
rated
104
items
divided
into
24
dimensions
80
criteria
age
group.
consisted
from
various
countries,
including
physicians
experience
old
psychiatry
or
geriatrics
well
nurses
psychologists.
response
rate
remained
consistent
rounds
(20/28,
71%
21/28,
75%).
In
total,
4
new
8
proposed
experts,
reached
86%
(24/28)
80%
(70/88)
criteria.
consensual
potentially
relevant
lack
hope
(21/21,
100%),
loss
interest
(27/28,
96%),
reactivity
pleasant
events
depressed
mood
(26/28,
93%),
previous
episodes
diagnosed
(19/21,
90%).
addition,
despondency,
gloom,
despair
(25/25,
100%);
(27/27,
circumstances
(28/28,
suicidal
ideation
suicide
attempt(s)
ruminations
96%);
recurrent
thoughts
death
feelings
worthlessness
(25/26,
critical
life
(20/21,
95%);
anhedonia
activities
93%);
pleasure
sadness
(24/26,
92%).
Moreover,
when
assessing
very
age,
duration,
number,
frequency,
severity
should
also
be
considered,
evidenced
high
agreement.
classification
elements
highlights
importance
multidimensional
approach
optimal
individuals
age.
offers
first
step
toward
improving
assessment
development
more
adapted
tool
could
improve
early
detection
intervention,
enhancing
quality
mental
care
Anxiety
disorders
in
older
adults
have
become
a
prominent
public
health
problem
due
to
their
concomitant
chronic
conditions,
reduced
quality
of
life
and
even
death.
However,
fewer
studies
been
conducted
on
differences
anxiety
among
individuals
different
aged-care
models,
the
interactive
relationship
between
influencing
factors
remains
unclear.
The
study
aimed
examine
disparities
prevalence
community-dwelling
institutionalized
related
factors.
Data
were
collected
from
Anhui
Healthy
Longevity
Survey
(AHLS)
Elderly
Caring
Social
Organizations
(AECSOS).
demographic
variables,
lifestyle
health-related
variables
6968
used
for
analysis.
symptoms
evaluated
using
Generalized
Disorder
Assessment
Scale
(GAD-7).
Binary
logistic
regression
models
Classification
Regression
Tree
model
(CART)
utilized
variables.
24.3%
16.7%
adults,
respectively.
Several
including
age,
gender,
residence,
education,
income
level,
live
alone,
number
diseases
showed
linkage
with
adults.
For
source
income,
exhibited
significant
association
anxiety.
We
noted
effect,
suggesting
that
female
an
level
less
than
6500
RMB
per
year
reported
disease
comorbidities
had
highest
likelihood
anxiety,
sources
such
as
pension,
subsidy,
family
providing,
resident
rural
areas
greatest
risk
experiencing
This
has
brought
light
higher
compared
Targeted
interventions
are,
therefore
emphasized
address
negative
impact
populations
at
risk.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 15, 2025
Multiple
chronic
diseases
in
the
elderly
significantly
impact
health
and
quality
of
life.
Identifying
key
comorbidities
their
formation
can
aid
controlling
progression.
Using
two
follow-up
datasets
from
CHARLS,
we
constructed
a
dependency
network
disease
progression
applied
multi-centrality
indicators
to
analyze
relationships
among
comorbidities.
(1)
Chronic
follow
power-law
distribution.
(2)
Common
include
heart
stroke,
dyslipidemia
liver
disease,
stroke.
(3)
Key
states
comorbidity
complete
health,
only
asthma,
arthritis,
stomach
with
arthritis.
(4)
Controlling
single
state
does
not
alter
final
distribution
The
show
complexity.
Reducing
individual
prevalence
requires
intervention
across
entire
process,
as
targeting
has
limited
on
overall
population
Menopause The Journal of The North American Menopause Society,
Год журнала:
2025,
Номер
32(3), С. 266 - 274
Опубликована: Фев. 21, 2025
Abstract
Objective
The
aim
was
to
develop
and
validate
a
nomogram
for
evaluating
the
risk
of
fatigue
in
climacteric
women
assess
its
clinical
application
value.
Methods
Clinical
information
collected
from
402
who
visited
tertiary
hospital
Shanghai
between
November
2023
April
2024.
Network
analysis
methods
were
utilized
analyze
core
symptom
(fatigue).
study
participants
then
randomly
divided
into
training
validation
cohorts
7:3
ratio.
Univariate
multivariate
logistic
regression
analyses
conducted
identify
independent
factors
women.
A
prediction
model
established
based
on
these
factors.
predictive
performance
evaluated
using
concordance
index,
area
under
curve,
receiver
operating
characteristic
Hosmer-Lemeshow
test,
calibration
curve
analysis.
Additionally,
decision
performed
model's
applications.
Results
Fatigue
is
identified
as
Educational
level,
chronic
diseases,
depression
status
are
influencing
menopausal
cohort
0.813
(95%
CI,
0.743-0.884)
0.759
0.637-0.879),
respectively,
indicating
that
possesses
good
discriminative
ability.
shows
consistency
predicted
probabilities
actual
both
cohorts.
P
values
test
sets
0.233
0.197,
calibration.
Finally,
demonstrates
has
utility.
Conclusions
simple
three
(educational
status)
can
aid
clinically
predicting
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 25, 2025
Background:
Comorbidity
of
depression
and
anxiety
is
common
among
adolescents
can
lead
to
adverse
outcomes.
However,
there
limited
understanding
the
latent
characteristics
mechanisms
governing
these
disorders
their
interactions.
Moreover,
few
studies
have
examined
impacts
relevant
risk
protective
factors.
Methods:
This
cross-sectional
study
involved
1,719
students.
Mplus
8.0
software
was
used
conduct
profile
analysis
explore
potential
categories
comorbidities.
R4.3.2
network
core
symptoms,
bridge
disorders,
evaluate
effects
Results:
Three
were
established:
"healthy"
(57.8%),
"mild
depression-mild
anxiety"
(36.6%),
"moderately
severe
depression-moderate
(5.6%).
"Depressed
mood",
"nervousness",
"difficulty
relaxing"
symptoms
in
both
depression-anxiety
comorbidity
Stress
perception
neuroticism
serve
as
bridging
nodes
connecting
some
are
thus
considered
most
prominent
Conclusions:
According
identified
this
study,
targeted
intervention
treatment
be
provided
groups
with
comorbid
anxiety,
thereby
reducing
comorbidities
adolescents.
World Journal of Psychiatry,
Год журнала:
2025,
Номер
15(3)
Опубликована: Фев. 26, 2025
Newborns
are
immediately
admitted
to
the
neonatal
intensive
care
unit
(NICU)
after
birth,
and
thus
mothers
suffer
from
pain
of
mother-infant
separation.
Some
worry
about
alterations
in
their
child's
condition
uncertainty
high
medical
costs
possible
sequelae,
which
frequently
cause
anxiety,
depression,
other
adverse
emotions.
To
investigate
anxiety
depression
status
children
NICU
its
related
factors.
A
convenient
sampling
method
is
adopted.
The
research
objects
included
191
Suzhou
Ninth
Hospital
Affiliated
with
University
January
2023
July
2024.
general
information
questionnaire,
personal
control
scale,
self-rating
scale
were
utilized
for
investigation.
Anxiety
factors
analyzed.
incidences
maternal
among
hospitalized
32.98%
(63/191)
23.56%
(45/191),
respectively.
Single-factor
analysis
reveals
that
family
monthly
income,
individual
sense
control,
gestational
age
child,
number
diseases
child
associated
experienced
by
mother
(P
<
0.05).
Multivariate
logistic
regression
revealed
income
5000
yuan
(RMB),
poor
32
weeks,
≥
3
kinds
all
Mothers
demonstrated
incidences.
nursing
staff
department
established
intervention
measures
each
factor,
strengthened
communication
did
a
good
job
psychological
counseling.
Patients
with
cardiovascular
disease
(CVD)
often
experience
anxiety
and
depression.
However,
the
central
bridge
symptoms
of
depression
among
patients
CVD
remain
unclear.
Network
analysis
is
a
statistical
method
that
can
reveal
visualise
complex
relationships
between
multiple
variables.
This
study
aimed
to
identify
in
anxiety-depression
network,
which
may
provide
potential
targets
for
preventing
intervening
A
total
1180
were
selected
from
Psychology
Behavior
Investigation
Chinese
Residents.
The
survey
was
conducted
July
10
September
15,
2021.
Face-to-face
electronic
questionnaires
distributed
respondents
by
investigators.
Generalized
Anxiety
Disorder
7
(GAD-7)
Patient
Health
Questionnaire-9
used
assess
depressive
CVD.
using
R4.02
network.
Among
included
this
study,
673
(57%)
male
507
(43%)
female.
More
than
half
(53.5%)
under
60
years
old.
mean
GAD-7
score
4.66
±
4.38,
169
(14.3%)
had
symptoms.
PHQ-9
6.29
5.29,
235
(19.9%)
Furthermore,
144
(12.2%)
people
both
In
network
symptoms,
"unable
sit
still
because
anxiety",
"feeling
afraid
something
terrible
about
happen",
bad
or
like
failure,
disappointing
oneself
family"
most
influential
We
also
found
happen"
"thoughts
dying
hurting
some
way"
pivotal
provides
new
insights
into
structure
These
identified
be
potentially
effective
CVD,
treatment
strategies