Vaccine Decision-Making Influences - Insights from Severe COVID-19 Survivors: A Qualitative Study

Medical & Clinical Research, Год журнала: 2024, Номер 9

Опубликована: Янв. 25, 2024

Vaccination have been critical for reducing death rates, severe illness, and long-term health risks; however, vaccine hesitancy has emerged as a key challenge. Understanding survivors’ perspectives on vaccination, given their direct virus experience elevated risks, is critical. This study explores COVID-19 vaccination decision-making among Romanian adult survivors to gain deeper understanding of the factors influencing acceptance within this societal context. Semi-structured interviews were conducted from November 2022-April 2023 with 30 participants (ages 35-76) previously hospitalized COVID-19. Before contacting COVID-19, 26.6% accepted vaccine, an additional 50% chose accept following discharge. Thematic analysis identified four main themes: Severe Illness Catalyst Vaccine Acceptancce, Adverse Reactions Fueling Hesitancy, Accepting influence trustworthy relationship and, General disbelief Conspiracy Theories. study’s findings indicate that many deeply affected by own experiences For these participants, traumatic was ultimately factor motivated them proactively seek out reliable information, ignore conspiracy theories, engage diligently in recommended safety behaviours. Nevertheless, still opted against after hospital qualitative advances intricacies underlying amongst survivors.

Язык: Английский

---

Ethical implications of developing RNA-based therapies for cardiovascular disorders

Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12

Опубликована: Март 15, 2024

The awareness concerning RNA-based therapies was boosted significantly after the successful development of COVID-19 vaccines. However, they can potentially lead to significant advances in other areas medicine, such as oncology or chronic diseases. In recent years, there has been an exponential increase number that were evaluated potential treatments for cardiovascular disorders. One not explicitly assessed about these is represented by their overall ethical framework. Some studies evaluate issues general targeting specific disorders (especially neurodegenerative) interventions developing Much less information available regarding associated with therapeutic strategies disorders, which main aim this study. We will focus our analysis on three topics: risk-benefit (including management public technologies), and justice (in both research clinical medicine).

Язык: Английский

---

When good messages go wrong: Perspectives on COVID-19 vaccines and vaccine communication from generally vaccine accepting individuals in Canada

Human Vaccines & Immunotherapeutics, Год журнала: 2022, Номер 18(7)

Опубликована: Ноя. 30, 2022

Vaccines are one of the most important and successful public health interventions to reduce spread infectious diseases. However, unlike childhood diseases routine vaccines, COVID-19 is a novel threat, vaccines may elicit specific anxieties. Through focus groups, we examine concerns attitudes toward vaccine expressed by individuals who accept vaccinations in Canada. We also conducted pre-focus group survey document participant towards general. While participants had received at least dose or intention get it, many concerns. First, felt anxious about quick development approval even if they recognized that have undergone clinical trials. Second, confused shifting guidelines regarding safety, changing interval between doses, mixing different brands. Finally, said abandoned when deciding whether vaccinated not. People generally mostly related inevitable uncertainties new (i.e. novelty, mandates, etc.). hesitancy, understood as novelty rapid implementation could be useful for understanding questioning from people vaccinations. Understanding hesitancy can provide valuable insights booster doses periodically needed not accepting these additional doses.

Язык: Английский

---

Parents' reasons to vaccinate their children aged 5–11 years against COVID-19 in Italy

Frontiers in Medicine, Год журнала: 2022, Номер 9

Опубликована: Авг. 2, 2022

Objectives The aims of this cross-sectional study were to investigate why parents decide vaccinate, as well the determinants, their children aged 5–11 years against COVID-19 in Italy. Methods survey was conducted from January through May 2022. All parents/guardians who came randomly selected days immunization centers for administration first dose vaccine child asked complete a questionnaire about socio-demographic characteristics, attitudes toward infection and vaccination, reason(s) regarding decision vaccinate child, source(s) information. Results A total 358 questionnaires collected. Parent's perception that is severe illness assessed using 10-point Likert scale, 7.5. overall mean scores risk having before after vaccination 8.1 6.3. significantly higher parents' level has been observed among those not university degree, with at least one chronic medical condition, perceived child. value respondent trust information provided by pediatricians on scale type 7.6. Female, disease, received pediatricians, needing had concern side effects vaccination. most common reasons vaccinating included wanting protect COVID-19, attend school less risk, prevent transmission family members, practice sport other activities risks. Participants degree more likely have vaccinated attending practicing Conclusions More publicity should be promoted which would increase coverage rates thus lower SARS-CoV-2 reduce occurrence COVID-19.

Язык: Английский

---

Prevalence and Determinants of COVID-19 Vaccine Acceptance in South East Asia: A Systematic Review and Meta-Analysis of 1,166,275 Respondents

Tropical Medicine and Infectious Disease, Год журнала: 2022, Номер 7(11), С. 361 - 361

Опубликована: Ноя. 9, 2022

Despite its importance in guiding public health decisions, studies on COVID-19 vaccination acceptance and determinants South East Asia (SEA) are lacking. Therefore, this study aims to determine the prevalence of vaccine variables influencing vaccine’s acceptance. This review is registered under PROSPERO CRD42022352198. We included that reported from all SEA countries, utilising five academic databases (Pubmed, MEDLINE, Cochrane Library, Science Direct, Google Scholar), three Indonesian (the Scientific Journal Database, Neliti, Indonesia One Search), two pre-print (MedRxiv BioRxiv), Thailand (ThaiJo Thai-Journal Citation Index). The analysis was conducted using STATA 17.0 with metaprop commands. for 71% (95%CI 69–74; I2 99.87%, PI: 68.6–73.5). Myanmar achieved highest prevalence, 86% 84–89), followed by Vietnam 82% (95% CI 79–85; 99.04%) Malaysia 78% 72–84; 99.88%). None ten studied (age, sex, education, previous infections, smoking marriage status, insurance, living together, chronic diseases, healthcare workers) were significantly associated result will be useful uptake SEA.

Язык: Английский

---