Neuroticism and Asthma: Mendelian Randomization Analysis Reveals Causal Link with Mood Swings and BMI Mediation DOI

D. Wu,

Xinyue Zhang, A. Li

и другие.

Journal of Asthma, Год журнала: 2024, Номер unknown, С. 1 - 16

Опубликована: Дек. 2, 2024

Background Neuroticism has been associated with asthma, but the nature of this relationship remains unclear due to limited understanding impact psychological factors on asthma risk. While is known affect various health outcomes, its specific role in respiratory conditions like not fully understood.

Язык: Английский

Exploring the association between socioeconomic inequalities in chronic respiratory disease and all-cause mortality in China: findings from the China Health and Retirement Longitudinal Study DOI Creative Commons
Zhuo Zhang,

Guoshuai Shi,

Faguang Jin

и другие.

Frontiers in Public Health, Год журнала: 2025, Номер 12

Опубликована: Янв. 7, 2025

Research on the inequality of chronic respiratory disease (CRD) is limited, and association between CRD all-cause mortality not well-established. Investigating distribution its associated risks essential for improving conditions developing targeted intervention measures. This study aimed to explore relationship inequalities in China. utilized nationally representative baseline data from China Health Retirement Longitudinal Study (CHARLS, 2011-2020, wave 1-wave 5), including a total 14,743 subjects. The concentration index was employed measure socioeconomic-related CRD, decomposition method used describe influencing factors. Cox proportional hazards regression model examine mortality. prevalence 11.79% (95% CI: 10.98, 12.66) -0.050 -0.075, -0.026), indicating certain degree prevalence. Chronic lung (concentration = -0.046, 95% -0.073, -0.019), asthma -0.102, -0.148, -0.056), asthma-chronic obstructive pulmonary overlap syndrome -0.114, -0.173, -0.055) also exhibited pro-poor distribution. analysis revealed that age, education level, economic status played substantial roles contributing observed inequality. Additionally, showed participants with had an increased risk (HR 1.49, 1.34, 1.65). Inequalities exists CRDs China, these diseases primarily concentrated among economically disadvantaged groups. increases Addressing root causes enhancing educational attainment individuals low socioeconomic can help improve situation.

Язык: Английский

Процитировано

0

The relationship between red blood cell distribution width and long-term prognosis of asthma: a population-based study DOI Creative Commons

Zhishen Ruan,

Yanyan Wang,

Yiling Fan

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 22, 2025

Statistically, 30% of asthma deaths occur among asthmatics with insignificant symptoms, which creates a social burden. We aimed to analyze the role erythrocyte distribution width (RDW) in prognosis asthma, especially patients symptoms. included 3039 adult (≥ 20 years) from National Health and Nutrition Examination Survey (NHANES). Cox regression was used assess association between RDW long-term mortality. adjusted three models reduce potential bias. Subgroup analysis is evaluate specific populations. In addition, receiver operating characteristic (ROC) curves were predictive effect on After mean follow-up 130 months, we found positive correlation aliquoting into thirds, high (RDW ≥ 13.0%) group had higher all-cause mortality (HR 1.66, 95% CI 1.18–2.34) respiratory 8.69, 2.03–37.3). There significant interaction male wheezing subgroups for Combining wheezing, that most increased mortality, but no also Furthermore, area under curve predicting death greater than 80%. Our study showed an poor patients. combination expected be biomarker management.

Язык: Английский

Процитировано

0

High ratio of epi-25-(OH)-vitamin D3 to 25-(OH)-vitamin D3 increases the risk of asthma attack in American asthma adults: a population study DOI Creative Commons
Biao Peng, Yi Xiong,

Ting Ouyang

и другие.

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Сен. 30, 2024

Язык: Английский

Процитировано

2

Neuroticism and Asthma: Mendelian Randomization Analysis Reveals Causal Link with Mood Swings and BMI Mediation DOI

D. Wu,

Xinyue Zhang, A. Li

и другие.

Journal of Asthma, Год журнала: 2024, Номер unknown, С. 1 - 16

Опубликована: Дек. 2, 2024

Background Neuroticism has been associated with asthma, but the nature of this relationship remains unclear due to limited understanding impact psychological factors on asthma risk. While is known affect various health outcomes, its specific role in respiratory conditions like not fully understood.

Язык: Английский

Процитировано

0